My daughter is 10 and has four main symptoms, all chronic: nausea, vomiting, diarrhea, pain in left abdomen. Started w/severe diarrhea 3 mos. ago. We did blood tests for parasites, bacteria, wheat allergy, CBC, celiac, dairy allergy. All negative. Didn't get better, went to a GI specialist at the children's hosp. Same tests plus a viral panel showed nothing. Since we have Crohn's and colitis in the fam, they did an endoscopy and colonoscopy with biopsies. Everything negative; they definitively ruled out Crohn's, colitis, celiac. After these biopsies the diarrhea got better but has since gotten quite severe. Making things worse, she started vomiting after these tests, along with nausea, sometimes severe vomiting episodes (2 hr. long spells). She is skinny and holding her weight, but barely—she should be gaining. GI doc pretty much "broke up" with us (that's what it felt like) and was surprised when our pediatrician called to say she was not getting better. She made an appt. to see us 3 wks later. Meanwhile, my daughter is sick as a dog! So we got an MRI of her brain to see if it's "abdominal migraines/cyclic vomiting." MRI showed no cancer or tumors or bleeding or infections—thank God. Neurologist followup appt determined she has no neurological problems. They ruled out cyclic vomiting (she's never had a normal spell w/o vomiting) and may want to followup with an EEG to look for autonomic nervous system dysfunction. We did an upper GI with a barium swallow test (small intest. follow-thru) and that was normal, so still no answers. That's where we are…waiting to see the GI again. So sad and frustrated. She has missed two and a half mos. of school and counting. She has never been constipated or had bloating or gas. Lots of sharp pains across belly and in the left corner. They also ruled out h. pylori but said she has GERD and some esophagitis as a result but the Prilosec has taken forever to kick in. Any ideas or similar stories? We can find nothing on Mayo site or elsewhere to rule in any possible diagnoses.