Started Repatha - Side Effects

God bless you. It’s not your imagination. My cardiologist was amazingly unaware of the symptoms (just as you described them) caused to some by all the medications you mentioned, including Repatha. When I couldn’t get out of bed (and I am a very active person) I had to stop the Repatha. My cardiologist blew me off. Some people have no side effects, others, like you and I, have debilitating side effects. My cardiologist seemed to think I was either faking the side effects or exaggerating them. His attitude was to take these medications no matter how sick they made me. It took much longer for the Repatha symptoms to leave my body than it took the various statins. I ultimately decided that I would rather live a shorter life and be happy and active than to live bed bound by a drug. And, I was concerned about what I was putting my body through each time I tried another one. Right now I am on Terzepitide with no side effects. (It is not a statin). It has potential to lower LPL. I will test again in a couple of months (after 6 months on it). I am going to report back here. At this point in my life I am skeptical about the numbers obsession especially when the “cure” for high numbers are drugs that make me sick. I’m old enough to have witnessed drugs come and go, one day they are miracle makers and the next they will kill you (statins feel like killers). My internist told me to quit worrying about it. He said I’m active, eat healthy and I’m enjoying my life. He also points to my 3.5 ratio.

God bless you. It’s not your imagination. My cardiologist was amazingly unaware of the symptoms (just as you described them) caused to some by all the medications you mentioned, including Repatha. When I couldn’t get out of bed (and I am a very active person) I had to stop the Repatha. My cardiologist blew me off. Some people have no side effects, others, like you and I, have debilitating side effects. My cardiologist seemed to think I was either faking the side effects or exaggerating them. His attitude was to take these medications no matter how sick they made me. It took much longer for the Repatha symptoms to leave my body than it took the various statins. I ultimately decided that I would rather live a shorter life and be happy and active than to live bed bound by a drug. And, I was concerned about what I was putting my body through each time I tried another one. Right now I am on Terzepitide with no side effects. (It is not a statin). It has potential to lower LPL. I will test again in a couple of months (after 6 months on it). I am going to report back here. At this point in my life I am skeptical about the numbers obsession especially when the “cure” for high numbers are drugs that make me sick. I’m old enough to have witnessed drugs come and go, one day they are miracle makers and the next they will kill you (statins feel like killers). My internist told me to quit worrying about it. He said I’m active, eat healthy and I’m enjoying my life. He also points to my 3.5 ratio.

@llynch17056
I, too, have a 3.6 ratio and knew I needed to stop after one injection (symptoms listed above). I decided to start pravastatin but at a 10 mg dose. I am in my early 80’s and found a NIH paper that indicated the “elderly” do well on a smaller dose. I will keep you all posted. The Repatha did get my LDL down into the mid 50’s but at the expense of making my lungs more vulnerable. The statin did not do that.

@llynch17056
Whats the 3.5 ratio?

Doctors only know what they are told. As I shared in some previous posts, my last injection (3rd) and last injection was on October 29th. Everyone's physiology is different. The Repatha brought my LDL to 37, total 104. So, what if you feel bad with mood swings, something I have never experienced.
I am now off of everything and feel 100% myself. I told my cardiologist you couldn't pay me enough to do a 4th injection. I don't believe any of these doctors understand the full scope of many of these medications. I find it extremely interesting that as my cholesterol falls then comes cognitive issues whether it was brain fog on the Lipitor or Crestor and then I develop mood swings on the Repatha. Its apparent to me regardless of what I am told, there is (for some people) a correlation here for what I experienced as the numbers fall. Certain side effects: Statistically insignificant when you read some of the trial notes. How convenient a term...

@dee53 To calculate your cholesterol-to-HDL ratio, divide your total cholesterol by your HDL ("good") cholesterol. A ratio of less than 3.5:1 is considered optimal, while a ratio above 5:1 is considered high risk. A lower ratio indicates a lower risk of heart disease. How to calculate your cholesterol-to-HDL ratio Find your total cholesterol number: This is the sum of your LDL, HDL, and other cholesterol types.Find your HDL cholesterol number: This is your "good" cholesterol level.Divide your total cholesterol by your HDL cholesterol:Example: If your total cholesterol is 200 mg/dL and your HDL is 50 mg/dL, the ratio is 4 (\(200\div 50=4\)). Interpreting your ratio Below 3.5:1: Optimal, indicating a very low risk for heart disease.3.5:1 to 5:1: Normal, indicating a moderate risk.Above 5:1: High risk, indicating an increased likelihood of heart disease.