@dee53 To calculate your cholesterol-to-HDL ratio, divide your total cholesterol by your HDL ("good") cholesterol. A ratio of less than 3.5:1 is considered optimal, while a ratio above 5:1 is considered high risk. A lower ratio indicates a lower risk of heart disease. How to calculate your cholesterol-to-HDL ratio Find your total cholesterol number: This is the sum of your LDL, HDL, and other cholesterol types.Find your HDL cholesterol number: This is your "good" cholesterol level.Divide your total cholesterol by your HDL cholesterol:Example: If your total cholesterol is 200 mg/dL and your HDL is 50 mg/dL, the ratio is 4 (\(200\div 50=4\)). Interpreting your ratio Below 3.5:1: Optimal, indicating a very low risk for heart disease.3.5:1 to 5:1: Normal, indicating a moderate risk.Above 5:1: High risk, indicating an increased likelihood of heart disease.