Moderna Vaccine not Creating antibodies for Transplant Patients

Posted by benlam11 @benlam11, Apr 25 11:16am

I'm a Liver and Kidney transplant patient (June 2019). I received both doses of Moderna in Feb and March. Now at the end of April I took an antibody test for efficacy and I show zero antibodies. I started questioning if I had antibodies after a research paper was published by Johns Hopkins speaking of this problem. Has anyone else experienced this problem and has anyone been advised by their MAYO doctors? The same study also mentioned Cancer patients and anyone else on immunosuppressant medications.

@colleenyoung

I also want to add a link to this related discussion:
– Third vaccine to boost antibodies against COVID infection? https://connect.mayoclinic.org/discussion/third-vaccine-to-boost-antibodies/

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I've been hearing about a medication called Remiron that is being considered for immunosuppressed people that haven't had an immune response to the Covid vaccine. I haven't asked my transplant team about their thoughts on this treatment so haven't got my hopes up yet, but it does sound promising. I'll ask at my virtual clinic appointment next week.

From my layman's perspective, it sounds like you are injected with the antibodies that your immune system is too suppressed to make in response to the vaccine like the rest of the population who are not immunosuppressed react by making themselves.

The article is titled "Regeneron says antibody cocktail prevented Covid when given as simple injection, not an IV". https://www.statnews.com/2021/04/12/regeneron-antibody-cocktail-covid-simple-injection/

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@terry14

I've been hearing about a medication called Remiron that is being considered for immunosuppressed people that haven't had an immune response to the Covid vaccine. I haven't asked my transplant team about their thoughts on this treatment so haven't got my hopes up yet, but it does sound promising. I'll ask at my virtual clinic appointment next week.

From my layman's perspective, it sounds like you are injected with the antibodies that your immune system is too suppressed to make in response to the vaccine like the rest of the population who are not immunosuppressed react by making themselves.

The article is titled "Regeneron says antibody cocktail prevented Covid when given as simple injection, not an IV". https://www.statnews.com/2021/04/12/regeneron-antibody-cocktail-covid-simple-injection/

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Terry, thank you for taking this question to your virtual clinic appointment next week. I'm sure many of us here would be interested to here their response specific to transplant patients.

Here is some further information about the use of monoclonal antibody therapies in the treatment and prevention of COVID. Monoclonal antibody therapy is not new, but it use against COVID is under research.

– Monoclonal antibodies: Update on this COVID-19 experimental therapy (Mayo Clinic, Feb 26, 2021) https://newsnetwork.mayoclinic.org/discussion/monoclonal-antibodies-update-on-this-covid-19-experimental-therapy/

– Monoclonal antibody treatment for COVID-19: Patient Story (Mayo Clinic Health System, Feb 8, 2021) https://www.mayoclinichealthsystem.org/hometown-health/patient-stories/monoclonal-antibody-treatment-for-covid-19

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@bosco17

Ivermectin is a proven anti-viral that works against covid-19. Why isnt this being used??? Also high doses of vitamin D are usefull against infection. TO THE MODERATORS– Get us answers!!

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@bosco17 I am pretty sure it is not the moderators job to respond to your personal orders. Perhaps that conversation is a more appropriate topic between you and your medical providers. In my experience the moderators facilitate community on this site which is obviously something I struggle with with respect to everyone on this site. I am working on it but I am not there yet.

Best always (or at lest trying)
s!

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