Anyone else out there with extremely high lipoprotein (a)?

Thank for your question and thanks for your awareness of supplements for this important issue.

The quick answer to your question is that I mostly get Lysine from 3 sources and I alternate between them. Most days I eat canned sardines or tuna "in water", not oil, as studies show water is a healthier choice. Tuna in water has about the same profile as sardines which equates to approximately 2-2,500 mgs per 3 oz can. Sometimes I eat a can of each at the same time with two boiled eggs and some mayonnaise. That would put a value close to 5,000 mgs on those days. Other days I use a scoop of vanilla flavored whey protein mixed with powdered milk and I eliminate one or the other of tuna/sardines. A scoop of whey protein equates to approximately +/- 2,300 mgs.

But Lysine is NOT the total answer. So what does Lysine do? Ask any Pharmacist (doctors may not know) Lysine is a wound healer. It's best known for cold sores around the mouth. taking lysine on a regular basis helps prevent outbreaks of cold sores and genital herpes.

Lipoprotein (a) is also a wound healer that operates in the endothelium (inside the cellular structure of the coronary arteries) of the heart. It's a natural response to the plaque build up in there. It's duty is to "patch up" the inside of the artery wall due to a Vitamin C deficiency. Vitamin C enchances this process. A minimal of 750 mgs of Vitamin C daily has been demonstrated for the process to work along with Lysine. I personally take upwards of 2,000 mgs per day...not all at once. (500 mgs 4 times through out the day). If a person is sensitive to ascorbic acid, (stomach issues), there are other forms, like "neutral" C.

Lp(a) is similar to LDL cholesterol, but it is even more “sticky” than typical LDL cholesterol, making it even better at sticking to artery walls and potentially causing harmful blockages.

If you go to your favorite search engine and type in ("name the lipoproteins"), the first paragraph below is basically what you will find.

"The main classes of lipoproteins, which are classified based on density, are chylomicrons, very low-density lipoproteins (VLDL), intermediate-density Lipoproteins (IDL), low-density Lipoproteins (LDL), and high-density Lipoproteins (HDL)."

Why is lipoprotein (a) never listed...as if it doesn't exist?

If cholesterol is the problem, why don't we see venouscelrosis? Plaque build up in your ear lobe, toes, nose etc? The same blood travels everywhere in the body.

Please study the Gulo gene.

The GULO gene encodes the enzyme L-gulonolactone oxidase, which is crucial for vitamin C biosynthesis in many animals, but is non-functional in humans and other primates due to mutations, resulting in the inability to synthesize vitamin C.

One more thing. MAGNESIUM. Studies show that the majority of people in the United States are deficient in Magnesium. In most of our trials, Magnesium in most cases will help (or sometime eliminate) irregular heartbeat beat. Please study.

Final thoughts. Doctors say (especially Cardiologist) say supplements create expensive urine. You get all the nutrients in your diet. Please let me know if you find all the vitamins and minerals in the foods most people eat today and I'll change my mind. Farmers only put N-P-K fertilizer in the soil. What about the other 60+ minerals that need to be there? The price to add these would cause a farmer to go broke. Plants need all minerals to give humans the daily nutrients. They can't if the minerals are not in the soil. If you know of a commercial farm that provides all nutrients back to the soil, please let me know.

Cardiologist and doctors die from cardiovascular disease just like the rest of us.

Why don't animals have heart attacks and strokes? Look it up.

thanks for the info very good stuff. I've been taking vitamin C a couple thousand milligrams for 50 years and eating low fat for probably 40 or 45 years and every time I wanted my doctor to test me for LP (a) he would tell me why we can't do anything about it so what does it matter. So I have inherited I guess the Gene for high LP (a). I have taken lysine in the past for cold sores and there is a theory that it helps bolster the immune system and some people were taking it when they caught Covid not sure if that had any effect. But Pauling felt that the solution was to use lysine and vitamin C. Also apparently amino acid proline helps?

have you seen any regression in your plaque or calcium in your arteries? Obviously it's important to slow down the process but it would be nice if the body could reverse it to a certain extent.

Yes you are correct. Studies have shown that Proline in combination with Vitamin C and Lysine demonstrate a very important combination. I don't know why I failed to mention that. As far as reversing this situation, there are some studies that indicate some reversal effects, but not conclusive. One study with the addition of Proline, did show reversal in the early stages of Atherosclerotic plaque.

To further answer your question, in 2005 at the age of 52, I had a nuclear medical exam for the heart, often called a nuclear stress test or nuclear cardiology imaging test. The reason this was done was because I wound up in the ER with almost a fatal arrhythmia. After the initial procedure of getting my heart back into to rhythm and some medication, the doctor wanted that specific test done. I was initially prescribed a Beta blocker and Aspirin....even that far back I was involved in Epidemiological studies, but not much focus on cardiovascular disease. The result at that time was zero blockage. A calcium test was never done.

A few days later, my studies focused 100% on the heart...and has continued to today at age 72.

So back to that event (a few days later)...I discovered Magnesium for AFib. At that time I could only find magnesium oxide. It was like a miracle. My AFib for the most part, disappeared. I currently take magnesium lysinate-glycinate due to it's high absorbability with no gastrointestinal issues.

Getting back to early studies, I had heard bits and pieces about Lipoproteins and Lipoprotein (a), Vitamin C etc, but like most people, didn't give it much thought. As the months went by, it became my ONLY thought.

In 2022, I became curious about how my coronary arteries were doing and voluntarily checked myself into the hospital and requested a heart Cath. The procedure was done and the results were close to those in 2005. I attribute the results to being on a combination of Vitamin C, Lysine and Proline....plus the fact that I had been taking a multivitamin along with some other supplements, plus avoiding processed foods as much as possible. I had also stopped smoking. As you and most people know, cigarettes create the most issues with the coronary arteries along with a deficiency in Vitamin C.

Today, I don't take any blood pressure medication. I don't take any blood thinners, well I take Aspirin. I also take a Beta blocker.

I don't like the word "blood thinner"., but it's a common phrase that maybe is easier to relate to. There are anticoagulant drugs and antiplatelet drugs. That's a subject for another day that's very important.

Just like Statins. Another important study for another day. One hint. Most Epidemiological studies prove that Statins increase the production of LP (a). It's a fact. Look it up. If you find a valid study that says otherwise, please let me know.

yes I did find that statins increase LP(a). i am also taking a baby aspirin. trying to get my LP (a) down. Q10 and Vit c, red wine, olive oil, green tea extract, and pomegranate juice. I am thonking about taking citrus bergamot and beeberine also.

What brand of whey protein did you use?

Those are all good choices. Glad to hear back from you. Stay in contact. Have a great weekend.