Brinsupri (aka Brensocatib)

Posted by scoop @scoop, Aug 12 10:55am

FDA approved Brensocatib today. Hooray for us. Let’s hope we have access to it as soon as possible and it gives us some measure of relief. Thank you to all the scientists and doctors and patients!
https://www.multivu.com/insmed/9347351-en-fda-approves-brinsupri-brensocatib

Interested in more discussions like this? Go to the MAC & Bronchiectasis Support Group.

No one is mentioning the most common adverse reaction being upper respiratory infection. For me that would be a very big concern as I have that going on chronically already.

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I don’t have Medicare Part D. I wonder how much it is without. ??

I thought I was healthy when I started Medicare.

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Profile picture for irenea8 @irenea8

No one is mentioning the most common adverse reaction being upper respiratory infection. For me that would be a very big concern as I have that going on chronically already.

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Yes, me too, on the chronic upper respiratory infections. If brinsupri -aka- brensocatib is supposed to help with exacerbations but a common adverse reaction is upper respiratory infection, then seems to me it is simliar to the Big 3 meds when I was on them for MAC: Do the side effects or adverse reactions make it worth taking? Do the benefits outweigh the disadvantages?

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Profile picture for mtyler @mtyler

Yes, me too, on the chronic upper respiratory infections. If brinsupri -aka- brensocatib is supposed to help with exacerbations but a common adverse reaction is upper respiratory infection, then seems to me it is simliar to the Big 3 meds when I was on them for MAC: Do the side effects or adverse reactions make it worth taking? Do the benefits outweigh the disadvantages?

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All side effects from any drug are concerning. If you experience do experience a side effect that is a problem, then you have the choice to stop taking that drug. Otherwise you don't know unless you try.

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Profile picture for notnancy88 @notnancy88

I don’t have Medicare Part D. I wonder how much it is without. ??

I thought I was healthy when I started Medicare.

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I am in the same boat. No part D yet. I think without any assistance it will cost over $7000 a month! Does anyone know at this point which Part D plan will cover Brinsupri? Or if you were prescribed Brinsupri and it was covered can you share which plan you are on?

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From my understanding, the way to figure out what it costs you is to get a prescription, fill out the inlighten forms. From there a rep will contact you and discuss payment and payment plans, which they have in place.

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Profile picture for irenea8 @irenea8

I am in the same boat. No part D yet. I think without any assistance it will cost over $7000 a month! Does anyone know at this point which Part D plan will cover Brinsupri? Or if you were prescribed Brinsupri and it was covered can you share which plan you are on?

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Hi Irene - No one can answer your question about which Part D plan will cover Brinsupri at this point. It is not yet on the formularies, and won't be added until they do the new ones for 2026.

Even then, most new, specialty drugs don't show up there - they are covered by "exception" - you need to go through an approval process.

This is what I mean - I have what many docs describe as a "golden" plan - Medicare Primary backed by my former employer's Blue Cross Blue Shield as secondary coverage (We pay $7000/year in premiums + Medicare B premiums for this.) Even they make us jump through hoops for every biologic and most newer proprietary (name brand) drugs. But I feel fortunate - once we get approved, our drug costs are "capped" by Part D at $2000 each - our copays get us there by November.

What I suggest is to contact Insmed to find out which companies have been most proactive in working with them.

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Profile picture for Sue, Volunteer Mentor @sueinmn

Hi Irene - No one can answer your question about which Part D plan will cover Brinsupri at this point. It is not yet on the formularies, and won't be added until they do the new ones for 2026.

Even then, most new, specialty drugs don't show up there - they are covered by "exception" - you need to go through an approval process.

This is what I mean - I have what many docs describe as a "golden" plan - Medicare Primary backed by my former employer's Blue Cross Blue Shield as secondary coverage (We pay $7000/year in premiums + Medicare B premiums for this.) Even they make us jump through hoops for every biologic and most newer proprietary (name brand) drugs. But I feel fortunate - once we get approved, our drug costs are "capped" by Part D at $2000 each - our copays get us there by November.

What I suggest is to contact Insmed to find out which companies have been most proactive in working with them.

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Thanks Sue. I know so little about Part D and where to start. So when you say contact Insmed to find out which companies do you mean which insurance might best cover it under part D? Who do you go through the approval process with for the exception? Your Part D insurer? I would not want to sign up for a plan only to find it did not cover the one drug I may end up trying. I would want to know in advance but is that possible?? I may not be making sense but like I said I know little about part D.

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Profile picture for irenea8 @irenea8

Thanks Sue. I know so little about Part D and where to start. So when you say contact Insmed to find out which companies do you mean which insurance might best cover it under part D? Who do you go through the approval process with for the exception? Your Part D insurer? I would not want to sign up for a plan only to find it did not cover the one drug I may end up trying. I would want to know in advance but is that possible?? I may not be making sense but like I said I know little about part D.

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It's more like which part D and in which state. I've been on part d for 2 years, moved states last year and very disappointed in coverages for the tier 3, 4 and 5's we need

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Profile picture for Rick @rstel7272

It's more like which part D and in which state. I've been on part d for 2 years, moved states last year and very disappointed in coverages for the tier 3, 4 and 5's we need

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what is tier 3 etc?

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