B-6 vitamin danger!

Posted by Lynsorensen @lynsorensen, Dec 11, 2017

With the assistance of a neurologist at Mayo Clinic, I have almost completely eliminated the uncontrolled muscle spasms now. First and foremost: beware of taking multi-vitamin capsules that have B6 listed. B-6 overdosage (which is contained in every multivitamin I found in stores and on the internet) can cause loss of muscle control and spasms in some people. So can gluten found in many foods so now I am also gluten free. I now work out with a personal trainer 3 days a week and do water aerobics another 2 days. Got off gabapentin and also clonazepam. Using CBD oil capsules each morning (no more opioids or chemicals) and using a CBD topical ointment to rub on my leg muscles each night. He says I don’t need him anymore! And I don’t. No more shaking or muscle cramps or pain. Still a little numbness but that is receding also.

Hello Ruthofanne, has your B6 come down since quitting Tumeric? Thanks so much, Sunnyflower

REPLY

I haven't gone to the lab because of the Corona Virus, so not sure where it is now. The neurologist seemed to think it would.

REPLY

Hi, today I have been reading thru the posts since 2017 on this discussion. The past few days I have been researching b complex supplements available on Amazon and have looked at probably 3 or 4 dozen (or more), eliminating any from consideration with over 5mg/cap. So just as an FYI for anyone looking for a GOOD b complex supplement with the most overall absorbable b components but also with with a fairly low B6 component, I finally settled on this one: 1 Body Vitamin B Complex, which had 5 mg per capsule. There are a couple available with only 2mg (about the daily recommended dose) but the other components are not the best (from as much as I have been able to determine) in terms of quality and absorbability. Before I knew about B6 toxicity and PN I thought the best b complex that I could find was one named Integrative Therapeutics Active B-complex, but after finding out that the 25mg per capsule was too much (for PN sufferers) I went searching for a better alternative. If anyone is interested here is the Amazon link to the one I found with lower B6 but comparable other components:
https://smile.amazon.com/gp/product/B00CFD0TC4/ref=ppx_yo_dt_b_search_asin_title?ie=UTF8&psc=1
Regards, Hank

REPLY

Hi Hank. You said that 25mg of B6 was too much, but there is 50 mg of B6 in the link you listed above from Amazon. I take a B Complex that has 25 mg of B6 and its manufactured and distributed from a company called NutriDyn here in Minnesota. http://www.nutridyn.com. Just FYI. , Margot

REPLY
@margottaylor

Hi Hank. You said that 25mg of B6 was too much, but there is 50 mg of B6 in the link you listed above from Amazon. I take a B Complex that has 25 mg of B6 and its manufactured and distributed from a company called NutriDyn here in Minnesota. http://www.nutridyn.com. Just FYI. , Margot

Jump to this post

You are right, sorry about that. I had two windows open each with a product and I (naturally) grabbed the wrong URL . Hre is the correct product with the lower B6 component that I now order:
https://smile.amazon.com/gp/product/B07QVKB66S/ref=ppx_yo_dt_b_asin_title_o00_s00?ie=UTF8&psc=1
Again, apologies. Hank

REPLY
@johnbishop

Hello @linnythepoo – I love that user name! Welcome to Mayo Connect – I’m happy you found us. It is a great place to ask questions, share your health concerns and learn what others with similar health issues are doing for treatment. Yikes is right from my perspective but I have no medical training or background. I would want to get an opinion or see a neurologist first.

Have you received a diagnosis of a form of neuropathy from a neurologist or had any tests to confirm the diagnosis?

I had a roundabout discussion through a 3rd party who I asked to check out a list of supplements that I’m taking for my peripheral neuropathy and this person giving the opinion was a neurologist. They said meh to my supplements and said they would probably recommend Metanx which contains L-methylfolate calcium, an active form of folate, and other essential B vitamins (B6 and B12) instead. B12 is in my list of supplements but I had already heard some bad stuff about B6 so I filed her opinion away under the category – it’s my body, my decision. It’s really a good idea to learn everything you can about your health condition and any drug used for treatment paying close attention to any side effects. I don’t have any medical training or background so this is just based on my opinion and how I’ve dealt with my own idiopathic small fiber peripheral neuropathy.

Here’s a more reliable source from the University of Virginia Health System – Peripheral Neuropathy and Vitamin B6 (PDF):
https://cancer.uvahealth.com/images-and-docs/neuropathy.pdf
Hope this helps,
John

Jump to this post

A wound and pain doctor I went to in Cinci put me on Metanx and it is promoted specifically for peripheral neuropathy in diabetics. I think I was on it 3 yrs along with her quackery medical device to stimulate nerves. But the pain got worse not better. When I finally went to neurologist, he said first off that the Metanx is probably making me worse not better. When tests came back for B levels they were at the highest toxic level!! It took 4 month s to get it out of my system. I still have the pain and numbness, but will not take a supplement again. He told me not to take any kind, not even a daily multi vitamin. That plus the doctor had put me on methadone for pain, was on it three years til my GP said she didn't know to do an EKG every 6 months to monitor my heart. Sure enough, again I was at a dangerous point with my QT wave – a very dangerous situation. So the GP took me of methadone cold turkey with nothing else. The withdrawal symptoms were worse than anything I ever experienced in my life. I have heard it is similar to withdrawals from heroin or similar drugs. Don't take Metanx!

REPLY
@jesfactsmon

You are right, sorry about that. I had two windows open each with a product and I (naturally) grabbed the wrong URL . Hre is the correct product with the lower B6 component that I now order:
https://smile.amazon.com/gp/product/B07QVKB66S/ref=ppx_yo_dt_b_asin_title_o00_s00?ie=UTF8&psc=1
Again, apologies. Hank

Jump to this post

Thanks. That looks good.

REPLY
@jesfactsmon

You are right, sorry about that. I had two windows open each with a product and I (naturally) grabbed the wrong URL . Hre is the correct product with the lower B6 component that I now order:
https://smile.amazon.com/gp/product/B07QVKB66S/ref=ppx_yo_dt_b_asin_title_o00_s00?ie=UTF8&psc=1
Again, apologies. Hank

Jump to this post

I just checked my Nature Made vitamin B complex and it has only 2mg of B6.

REPLY
@stefspad

I just checked my Nature Made vitamin B complex and it has only 2mg of B6.

Jump to this post

I did look at Nature Made for its low B6 level. But the 1 Body brand not only has a relatively low level of B6, but also seemed to be the best overall b complex of what I saw (although the Nature Made beats it on price). With the 1 Body brand I found that:

-the B12 was listed as Methylcobalamin (natural), not Cyanocobalamin (synthetic)
-the source of riboflavin is listed as riboflavin-5'-phosphate which is its active form
-the source of B9 is 5MTHF rather than folic acid; 5MTHF is more completely metabolized according to sources I have read

Based purely on what I read I chose what seemed like the best overall b complex supplement of the ones I looked at.

REPLY
@jesfactsmon

I did look at Nature Made for its low B6 level. But the 1 Body brand not only has a relatively low level of B6, but also seemed to be the best overall b complex of what I saw (although the Nature Made beats it on price). With the 1 Body brand I found that:

-the B12 was listed as Methylcobalamin (natural), not Cyanocobalamin (synthetic)
-the source of riboflavin is listed as riboflavin-5'-phosphate which is its active form
-the source of B9 is 5MTHF rather than folic acid; 5MTHF is more completely metabolized according to sources I have read

Based purely on what I read I chose what seemed like the best overall b complex supplement of the ones I looked at.

Jump to this post

Hello HankB, I am late in the game so please forgive if I am asking too much. Has it been determined that B6 should be at a certain level and that there is an established amount we should take or not exceed in our supplements, or it can or will worsen our neuropathy symptoms? I apologize I just don't feel good enough to absorb all the info. Blessings, Sunnyflower

REPLY
@sunnyflower

Hello HankB, I am late in the game so please forgive if I am asking too much. Has it been determined that B6 should be at a certain level and that there is an established amount we should take or not exceed in our supplements, or it can or will worsen our neuropathy symptoms? I apologize I just don't feel good enough to absorb all the info. Blessings, Sunnyflower

Jump to this post

Hi @sunnyflower, I am of course no doctor but the literature online mostly seems to indicate that most people don't need more than 2mg per day of B6. At some amount over that B6 could become toxic and possibly cause neuropathic symptoms according to some health websites. So my wife and I are starting to take the supplement I linked to earlier, 1 Body Vitamin B Complex, for the reasons stated in my earlier post. Previously we were happy with what we were taking but now we know that brand has 25 mg per capsule and so we have switched. Best, Hank

REPLY

@jesfactsmon, @sunnyflower, @stefspad, @keb, and others searching for vitamin B6 information. The following links were posted earlier in the discussion but I thought I would repeat them here in case you haven't seen them.

Vitamin B6 Toxicity
http://www.easy-immune-health.com/vitamin-b6-toxicity.html
B Vitamins for Neuropathy and Neuropathic Pain
https://www.omicsonline.org/open-access/b-vitamins-for-neuropathy-and-neuropathic-pain-2376-1318-1000161.php?aid=90896
B6 section it explains — too much or too little gives neuropathy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/
FDA Safety Alert: Biotin Can Affect Medical Test Results
http://cle.clinic/2G6Mp4y
NIH – Nutritional Neuropathies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/

Vitamin B6 Toxicity Revisited: A Case of Reversible Pyridoxine-associated Neuropathy and Disequilibrium. (P4.021)
http://n.neurology.org/content/90/15_Supplement/P4.021

REPLY
@johnbishop

@jesfactsmon, @sunnyflower, @stefspad, @keb, and others searching for vitamin B6 information. The following links were posted earlier in the discussion but I thought I would repeat them here in case you haven't seen them.

Vitamin B6 Toxicity
http://www.easy-immune-health.com/vitamin-b6-toxicity.html
B Vitamins for Neuropathy and Neuropathic Pain
https://www.omicsonline.org/open-access/b-vitamins-for-neuropathy-and-neuropathic-pain-2376-1318-1000161.php?aid=90896
B6 section it explains — too much or too little gives neuropathy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/
FDA Safety Alert: Biotin Can Affect Medical Test Results
http://cle.clinic/2G6Mp4y
NIH – Nutritional Neuropathies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/

Vitamin B6 Toxicity Revisited: A Case of Reversible Pyridoxine-associated Neuropathy and Disequilibrium. (P4.021)
http://n.neurology.org/content/90/15_Supplement/P4.021

Jump to this post

@johnbishop Good article,s in there John especially the one about Osteoporosis

REPLY

Thx very much John and lioness. Appreciate it. Overwhelming for my brain in the degree of pain I 'm in that literally makes me fight for my sanity. Just info, not a complaint. I' m blessed beyond measure! Basking in the unfathomable love of Christ, Sunnyflower

REPLY
@sunnyflower

Thx very much John and lioness. Appreciate it. Overwhelming for my brain in the degree of pain I 'm in that literally makes me fight for my sanity. Just info, not a complaint. I' m blessed beyond measure! Basking in the unfathomable love of Christ, Sunnyflower

Jump to this post

That is great that you have a strong faith @sunnyflower. With all the stupidity in our world today, with people arguing about ridiculous things, politics, etc., I just wish most people appreciated how good their lives are and enjoy the blessings of just being able to live without suffering as some such as you do, I think their lives would be infinitely better. You are an inspiration and I am glad to hear you describe the strength that your faith gives to you. All the best to you.

REPLY
Please login or register to post a reply.