B-6 vitamin danger!

Thank you for your story. I’m sorry what happened but you’ve given me hope. I have a double copy gene mutation where I can’t not absorb folate b12. Got neuropathy from that until I learned how to properly supplement with the methyl formula . However the gen mutation requires also taking b6. Being it’s a water soluble vit I didn’t know you could ever get toxic on it . I too took way way too much since 2016. Today the muscle weakness, cramps , photo sensitivity , lack it muscle ordination, chest pains, shortness of breath have worsened to the point I’m hone bound and can do nothing. After great research I and reviewing history’s of lab reports I discovered I had been toxic in b6 all these years and conductor ever brought it to my attention as alarming. Now I wait to see a neurologist fearful my symptoms will not ever reverse after this long. I did learn once stopping b6 symptom get worse. Which I’m experiencing. Read an article from Australia who this happened to him. Their country this trying to get warning labels but on energy drinks supplements etc. FYI. Magnusium often includes it with their supplements. Even RX meds . I was taking Magnusium with my b6. Magnusium boost absorption. Thank you for your words of hope. I needed it. Pray may knows about this.

I’ve got double copy mthfr 0677 tt I only have 30 function of absorption of folate b12. I too have taken a lot of b6 because it’s needed for absorption with folate b12. FYI. With this gene only take Methylfolate and Methylcobaline Crk spelling . Other formulas will not be absorbed. Never take folic acid as your body can not absorb with this gene therefore the folic acid just floats around un used wasted causing toxic build up causing more symptoms with the mutation. I’ve searched for 15 years to find someone who knew how to help me manage this. Doctor are not taught about nutrition. They clearly have no education in gene issue that involve nutrition or dna. I pray you can find a doctor who knows about this gene I’ve been my own doctor and was doing ok with it until this b6 toxicity. Not only do I have neuropathy from being deficient for a life time but the b6 has caused all body parts to not function. Muscle never coordination I’ve learned a lot about the mutation but your welcome to contact me. I’ll share what I know. I’m new to this platform so not sure how to navigate. Sorry for my typo. I can’t feel my hands. My neurologist sent me home with a Rx of peripheral neuropathy saying my b12 looked fine. Years later learned blood test only show what’s in your blood. It fails to show how much you are capable of absorbing. There are some formulas that can better help show your absorption levels. So mthfr people must maintain higher than normal levels of folate and b12. Don’t don’t know this. It’s a tricky trial an error knowing your sweet spots. Wish you could find could help. Tallahassee is clueless here. Wish you best and sending you prayers

B6 toxicity is almost always B6 hidden in foods and supplements. Finding out where and stopping consumption is step one.
It’s fairly new here is Australia (2020 it started getting recognised). There are quite a few medical papers on line but you have to go hunting - there is also a lot of rubbish.
I find I have more information than my GP but at least he is supportive and I go for blood tests every month.
I have only been on the journey for 5 months. I’m currently in ‘dip’ for no apparent reason. I’m hoping it’s a sign if repair activity.
Once you get blood serum levels (of B6) in the normal range it must then come out of your cells. The nerves that have been damaged must regrow their myalin sheath and vasodilation will occur. This a causes cramping in the muscles.
Drink a lot of water. Low dose regular magnesium.
Inflammation (if you have other injuries) hinders the process, so any anti- inflammation is helpful.
Exercise is important but keep it regular and gentle to avoid inflammation.
Avoid sugar as that can also cause inflammation.
I’m still learning. I get terrible fatigue but I figure my body is working hard so I give it as much rest as it needs. I’m a 73yo female with access to fresh food and good health care. I consider myself very lucky.
I read and research but take time for lots of distractions. I hope my body is repairing and I don’t want to do anything to make its job harder. Sometimes less is more.
Good luck to all on this journey.

Thank you so much for all of your good information and wish you all the best in your recovery.

I been looking for a vitamin that doesn’t have b6 in it. Hard to find plus there seems to be b6 in so many vegetables and fruits. Anyone have any advice?
Thanks

B6 in food will not hurt you. It’s a good and necessary vitamin. So good that it was thought that putting it in bread and cereal would help people. Because it’s water soluble it was long thought excess would be excreted. They have learned it stays in tissue (cells) 2-5 years. Medicine is learning all the time.
In healthy adults that get a healthy balanced diet there should be no need to take any supplements.
The multi billion dollar supplement industry does not want to hear this.
Eat healthy food. Don’t take supplements is my humble advice. If you’ve had high B6 or B12 readings it will take about 6 months for your blood serum levels to read as ‘normal’ and up to 2 years for it to exit your system and for the myelin sheaths to grow back on the nerve endings.
If you’ve only had it a short while many will repair. If it’s long term (chronic) some damage will be permanent but you will get much better.
Lethargy, tingling, numb extremities, poor response to hot and cold (hard to control your body temperature), burning mouth and hot feet are some symptoms. You may get a couple. You may get them all. If it’s bad there is joint pain, bone pain and headaches; and gut and brain issues. It affects your nervous system.
If you have bad symptoms work with a trusted medical professional and always get blood tests. They will tell you your situation. This is too important to guess.
Do not be afraid of healthy food that contain vitamins.
Avoid fat, sugar and highly processed foods. And, I’ll say it again, don’t take supplements - a lot of on line advice is written by companies that make and sell supplements. This industry is not regulated and it makes billions!
Good luck. You are obviously aware, concerned and doing research. It will just take time (rest, light exercise, a healthy diet and no supplements).

As @lorry said, vitamin B6 eaten naturally in foods will not hurt you. The recommended daily intake of B6 is 1-3mg a day. It's when it's added to supplements at much higher levels that problems may occur.

Unknown to me, my daily magnesium supplement contained 60mg of added B6 and that caused blood levels to be very high, and according to my pathology report, it posed a risk for peripheral neuropathy. My blood results were normal within a few weeks of stopping the magnesium supplement and switching to a brand that didn't include B6. But it takes longer for B6 to leave cells (as lorry said) and there's no way to measure that. More is not better with B6. Just keep in mind the recommended daily allowance of 1-3mg when looking at supplement ingredients. Best to get what you need through diet.