Smoldering Multiple Myeloma SMM Bloodwork numbers

Posted by DMD81 @dmdinapoli81, 6 days ago

I am interested in what everyone's numbers were at time of diagnosis of Smoldering Multiple Myeloma SMM? Were you Kappa or Lamba?
kappa free light chain in(mg/L):,
K/L Ratio(mg/L,):,
M-Spike(g/dL):

If Lambda
Free Lambda Lt Chains,S (mg/L):

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I am newly diagnosed with SMM('26) (was IGG Kappa MGUS '20)and wanted to get an idea as some say my Kappa and ratio numbers are high. what other numbers do you track?
Free Kappa Lt Chains,S (mg/L): 112
K/L Ratio(mg/L,): 10
M-spike 1.4

REPLY

Just for comparison:
I’ve had IGA Kappa MGUS for at least 11 years.. My last results were the following:

Free Kappa Light Chains (mg/L): 90.5 Range 3.3-19.4
Free Lambda Light Chains (mg/L): 11,7 Range 5.7-26.3
K/L Ratio: 7.71 Range 0.2-1.65
M-spike 0.6 g/dl

I was told that I am still at the MGUS stage and that I have not moved to Smoldering yet.

I am also interested in what new results would be necessary to show I had moved to the Smoldering category.

REPLY

I am still Light Chain SMM and my Kappa levels were:
Kappa: 89 mg/l
Lambda: .84
Ratio: 101

There is no m-spike with Light Chain SMM.
My numbers have gone down a little since I was diagnosed (without treatment). I am on a watch and wait schedule where my bloodwork is tested every two months for now.

REPLY
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