Smoldering Multiple Myeloma SMM Bloodwork numbers
I am interested in what everyone's numbers were at time of diagnosis of Smoldering Multiple Myeloma SMM? Were you Kappa or Lamba?
kappa free light chain in(mg/L):,
K/L Ratio(mg/L,):,
M-Spike(g/dL):
If Lambda
Free Lambda Lt Chains,S (mg/L):
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I am newly diagnosed with SMM('26) (was IGG Kappa MGUS '20)and wanted to get an idea as some say my Kappa and ratio numbers are high. what other numbers do you track?
Free Kappa Lt Chains,S (mg/L): 112
K/L Ratio(mg/L,): 10
M-spike 1.4
Just for comparison:
I’ve had IGA Kappa MGUS for at least 11 years.. My last results were the following:
Free Kappa Light Chains (mg/L): 90.5 Range 3.3-19.4
Free Lambda Light Chains (mg/L): 11,7 Range 5.7-26.3
K/L Ratio: 7.71 Range 0.2-1.65
M-spike 0.6 g/dl
I was told that I am still at the MGUS stage and that I have not moved to Smoldering yet.
I am also interested in what new results would be necessary to show I had moved to the Smoldering category.
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1 ReactionI am still Light Chain SMM and my Kappa levels were:
Kappa: 89 mg/l
Lambda: .84
Ratio: 101
There is no m-spike with Light Chain SMM.
My numbers have gone down a little since I was diagnosed (without treatment). I am on a watch and wait schedule where my bloodwork is tested every two months for now.
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3 ReactionsI have IgA Kappa Free Light Chain SMM. One can have an M spike with LC SMM; mine is 1 (near zero a year ago). I was diagnosed with MGUS 10 years ago and my numbers started ramping up 3 years ago (SMM last year). I'm high risk due to SMM type and 1q21 gain, so on the 2 mo bloodwork plan. If/when I reach a threshold, I will start I-VRD treatment. SMM can ramp up quickly, can also plateau, and rarely can subside some. The waiting is hard. My numbers are:
Kappa 932 mg/L (378 six months before and still MGUS)
Kappa/Lambda ratio 75 (32 six months before, MGUS)
M Spike 1 (6 mo before near zero)
BMB 9/25 had 15% deranged plasma cells (10% is usually SMM, but hematologist still thought MGUS due to bloodwork)
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3 ReactionsI am fighting MGUS progression to cancer with climbing m-spike starting .2 in 2012 now at .7 (IGM Lambda) and high IGM (over 500 with normal high range going to 250. I have started a moderately low carb diet, low calories (under 1,000 day) and taking 400 mg of ecgc plus drinking matcha tea, w/a focus on berries and high fighting cancer foods and high polyphenols (expensive rich EVOO, organic foods, cacao in coffee, etc.). I will check lab numbers in June.
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1 Reaction@crunchywfwf yikes, that doesn’t sound like enough caloric intake to keep you going. Are you working with a dietician? I worry (It’s what I do) because you need your stamina intact to do battle with this disease should you need to.
Hugs.
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1 Reaction@crunchywfwf I am on more of a Mediterranean diet, heavy on anti-inflammatory foods, with celiac I can't eat most processed foods, and especially avoid ultra-processed. I also take about 10 gm/day of bioavailable turmeric (1.5-2 gm curcuminoids) Bioavailable means with lipids (fats) and pepperine to increase GI absorption. Exercise is also very important for your immune system, stress relief, and staying strong in our fight against these nasty cells. I don't know if a fasting diet (1000 cal) is useful or harmful for looming cancer. It would be good to check with a dietician to make sure you are getting a balance of nutrition and calories.
Thank you, can you recommend the specific Tumerico’s you take? I have tried dozens over the years and find taking multiple pills at once upsets my stomach as does just taking the spice in its bright orange natural state. Yea, I walk 45 minutes 5 days a week and workout with weights 3 days for 1.5 hours.
@pmm Yes, I am working with an Oncologist Dietian and am just trying to get my waistline from 32” to 30”. I will see my PC in June and be measured.
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1 ReactionI was recently diagnose with MGUS my M protein is 0.13 I'm scared and trying to process this I've always been so healthy I work out 5 days a week I eat good This just came out of no where I'm trying to process it all and what this could mean for my life🤦🏽♀️I have to admit I'm scared and stressed