John Hopkins Webinar on transplant recipients and vaccines

Posted by bosco17 @bosco17, Mar 24 6:34am

They said after first shot 17 out of 800+patients had only a minimal antibody reaction .Also being on mycophelonate reduces effect of vaccines.WHATS GOING ON ??????

And, Calcineurin Inhibitors, Tacrolimus and Cyclosporine, are designed to inhibit T Cells. So, we won’t be protected from those either! That leaves “Memory Cells”…so, let’s hope they have good memories!! The study also found no increase in neurological symptoms. I for one had a definite increase in neuropathy symptoms.

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Here im also wondering a lot about this whole get our body to produce the enemy protein so our body will recognize it later. It's just doesn't make sense to approach it that way! Well we will see I guess. Our bodies are so complex and there is still so much we don't know. Time will tell, I guess that's why it takes a few years with a new virus to really know enough to fully approve any vaccine. For me tho and from discussions with my Infectious Disease Doctor the therapeutics are also having success. I'm still in the category that true immunity will happen as our bodies see the real virus and learn how to defend against it.
Blessings Everyone
Dana

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I believe the stats showed that 17% of those tested after dose 1 developed antibodies, not only 17 persons. It is a bit scary, as he said, yet others in the chat room shared their very high numbers of antibodies after dose 2.
I would have liked to have seen a breakdown by organ; also, each individual patient has a unique combination of meds. I'm wondering how deep the analysis will go with that. Will they create an algorithm to explore each med, each dosage, and each combination.
I appreciate their efforts as the clinical trials prior to vaccine distribution did not include us. This research is important.
Looking forward to seeing more. For now, even after bring vaccinated, I will continue with precautions.
Truth is, we are the ones who can teach others that none of us are going back to a past normal. The virus has changed us, just like our transplants have.

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@athenalee

And, Calcineurin Inhibitors, Tacrolimus and Cyclosporine, are designed to inhibit T Cells. So, we won’t be protected from those either! That leaves “Memory Cells”…so, let’s hope they have good memories!! The study also found no increase in neurological symptoms. I for one had a definite increase in neuropathy symptoms.

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I indicated on their survey that I developed an inflammation in my parotid gland post dose 1. Also, dizziness in the evening. I'm seeing an ENT at Mayo for this. Not fun!

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@estrada53

I indicated on their survey that I developed an inflammation in my parotid gland post dose 1. Also, dizziness in the evening. I'm seeing an ENT at Mayo for this. Not fun!

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I'm on sirolimus, mycophenolate and prednisone.

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I registered, and I received a confirmation but cannot find how to view it today. Anybody have a solution for how/where to view it today?

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@estrada53

I believe the stats showed that 17% of those tested after dose 1 developed antibodies, not only 17 persons. It is a bit scary, as he said, yet others in the chat room shared their very high numbers of antibodies after dose 2.
I would have liked to have seen a breakdown by organ; also, each individual patient has a unique combination of meds. I'm wondering how deep the analysis will go with that. Will they create an algorithm to explore each med, each dosage, and each combination.
I appreciate their efforts as the clinical trials prior to vaccine distribution did not include us. This research is important.
Looking forward to seeing more. For now, even after bring vaccinated, I will continue with precautions.
Truth is, we are the ones who can teach others that none of us are going back to a past normal. The virus has changed us, just like our transplants have.

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Yes, you’re correct, it’s 17%. We’ll just have to keep following the results and be hopeful. I’m on both Tacrolimus and MFF, so both seem to present issues with developing resistance to the virus.

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I am on Tacrolimus and got the virus the end of December. Mayo told me to wait 3 months before I get the shot to let my antibodies build up. Sounds like getting Covid is beneficial in some ways.

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I’m a participant in the Hopkins study. Liver transplant (A1AT) 5 years out, currently just on 2mg daily of Tacro. On first dose of Pfizer vaccine, I developed less than 0.48 (no antibodies). Very disheartening! However, 30 days after second dose, I was just notified I tested positive for antibodies. So delayed response for me!

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@athenalee

Yes, you’re correct, it’s 17%. We’ll just have to keep following the results and be hopeful. I’m on both Tacrolimus and MFF, so both seem to present issues with developing resistance to the virus.

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Did anyone catch the link to view the webinar post presentation? I would like to share this with my family. Thanks.

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@kedwards73

I’m a participant in the Hopkins study. Liver transplant (A1AT) 5 years out, currently just on 2mg daily of Tacro. On first dose of Pfizer vaccine, I developed less than 0.48 (no antibodies). Very disheartening! However, 30 days after second dose, I was just notified I tested positive for antibodies. So delayed response for me!

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Congratulations! Maybe we will all have the same response.

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@estrada53

Congratulations! Maybe we will all have the same response.

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TU! I certainly hope so.

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