Is the PARI eRapid® Nebulizer System worth what it costs?

Posted by spectrumcyclist @spectrumcyclist, Jul 9, 2025

Does anyone have any long-term experience with the PARI eRapid® Nebulizer System?

After 15 years of lugging different large and small nebulizers around when traveling, I am ready to spend a lot of money on something small, easy to clean, and fast, so long as it is rugged and will last a few years. I have to nebulize four vials of stuff (including saline) twice daily. I'm not loving traveling anymore because of the chore of having to spread out all my stuff, sometimes with very little available surface area, wherever I am, not to mention having to wake up an hour before everyone else to nebulize.

Information from anyone who knows this product is appreciated.

Interested in more discussions like this? Go to the MAC & Bronchiectasis Support Group.

Profile picture for lvnl @lvnl

I'm in the "ENCORE" study, which has many sites in U.S. & internationally and is comparing Arikayce vs placebo, + ethambutol + Azithromycin. I'm fortunate to be treated at the NYU BE/MAC program. They are heading up this study. And several others as well, so many patients there have ready access to cutting edge research & treatment.
https://clinicaltrials.med.nyu.edu/clinicaltrial/1544/encore--randomized-double-blind/

Jump to this post

Are you treated for mac or bronchiectasis in this study?

REPLY

This is a study for newly diagnosed MAC patients.

REPLY

I bought the misty portable nebulizer from amazon for $35 & I cant believe no one ever told me about this. You can send it to 10 or 20 minutes. And it has one cycle where you put boiling sterile saline in the cup and hit five minutes to sterilize the internal system. It is a small handheld device that is quiet and does the trick.

REPLY
Profile picture for robot @robot

I bought the misty portable nebulizer from amazon for $35 & I cant believe no one ever told me about this. You can send it to 10 or 20 minutes. And it has one cycle where you put boiling sterile saline in the cup and hit five minutes to sterilize the internal system. It is a small handheld device that is quiet and does the trick.

Jump to this post

How long have you owned it? Amazon indicates this is a frequently returned item,

REPLY

I've had it for 6 months & i love it because its rechargeable so its not connected to a plug in when i use it. I'm wondering why it was returned as all the reviews were positive.

REPLY
Profile picture for scoop @scoop

To sterilize the eRapid or eFlow (same thing, different name; one is called one in the U.S. and the other in Europe), I soak in hot tap water with a drop of Dawn. Then I sterilize in Boloco baby bottle sterilizer at home. On the road I use either a ramen pot for boiling or Grownsy baby bottle sterilizer. I used to sterilize everyday, now I go every couple to few days for sterilization but everyday I give it a Dawn soak. How often for cleaning/sterilization is personal preference taking into account your comfort level and disease state.

Jump to this post

@scoop I'm using the eRapid that came with my Arikayce, for saline. I didn't tolerate the Arikayce so am now just on Ethambutol and Azithromycin but used the eRapid for recent travel and now that I'm home, figuring out if I can use it instead of my Ombra with Aeroclipse XL, as it's much faster and silent, for everyday use.
I would love to use the Bololo baby bottle sterilizer instead of boiling for sterilization but I thought that was not advised. As in all of the info related to management of this condition there are multiple opinions that often come off as hard fast rules. Are you using it daily/2x/day and sterilizing in the Bololo daily with no ill effects?
One more question: The Arikayce medication boxes came with a new aerosol head and instructions to change the head each week. I'm thinking that's because the Arikayce med clogs the head but not necessary with saline. Thoughts? Thanks for the advice!

REPLY
Profile picture for minute22 @minute22

@scoop I'm using the eRapid that came with my Arikayce, for saline. I didn't tolerate the Arikayce so am now just on Ethambutol and Azithromycin but used the eRapid for recent travel and now that I'm home, figuring out if I can use it instead of my Ombra with Aeroclipse XL, as it's much faster and silent, for everyday use.
I would love to use the Bololo baby bottle sterilizer instead of boiling for sterilization but I thought that was not advised. As in all of the info related to management of this condition there are multiple opinions that often come off as hard fast rules. Are you using it daily/2x/day and sterilizing in the Bololo daily with no ill effects?
One more question: The Arikayce medication boxes came with a new aerosol head and instructions to change the head each week. I'm thinking that's because the Arikayce med clogs the head but not necessary with saline. Thoughts? Thanks for the advice!

Jump to this post

@minute22 I cannot answer the question regarding Arikayce because I’ve never used it. Twice a day I use the E flow with hypertonic saline prior to airway clearance. My current habit, which I often seem to be tweaking, is to soak in hot tapwater with some dawn after each use. At the end of the day, I sterilize it in the Bololo baby bottle sterilizer. This sterilizer along with others have been deemed effective by Dr. Jenn Honda. She presented not too long ago on use of baby bottle sterilizers for our equipment. I think her presentation can be found in the ABCs of bronchiectasis in this forum. Pari recommends the handset be replaced every six months.

PS-here’s the presentation by Dr. Jenn Honda. Well worth watching.
https://m.youtube.com/watch

REPLY
Profile picture for scoop @scoop

@minute22 I cannot answer the question regarding Arikayce because I’ve never used it. Twice a day I use the E flow with hypertonic saline prior to airway clearance. My current habit, which I often seem to be tweaking, is to soak in hot tapwater with some dawn after each use. At the end of the day, I sterilize it in the Bololo baby bottle sterilizer. This sterilizer along with others have been deemed effective by Dr. Jenn Honda. She presented not too long ago on use of baby bottle sterilizers for our equipment. I think her presentation can be found in the ABCs of bronchiectasis in this forum. Pari recommends the handset be replaced every six months.

PS-here’s the presentation by Dr. Jenn Honda. Well worth watching.
https://m.youtube.com/watch

Jump to this post

Thanks @scoop for the reply. I’m using it for saline although it was
supplied to me for use with Arikayce (so paid for) which I used briefly
before discontinuing. I think the recommendation is to change the aerosol
head every week when using with Arikayce. Since I’m using with saline I
think I can stick to the every 6 months recommendation. I’ll check out the
presentation. Thanks for sharing.
On Mon, Nov 17, 2025 at 11:47 AM Mayo Clinic Connect < nf+ecb58965+84856872@n1.hubapplication.com> wrote:

> ## reply above this line ##
>
>
> Mayo Clinic Connect
> @scoop
> < https://connect.mayoclinic.org/member/00-ae262dedf13dfc96328105/;
> mentioned you in comment on Mon, Nov 17.
>
> *Message*
> @minute22 I cannot answer the question regarding Arikayce because I’ve
> never used it. Twice a day I use the E flow with hypertonic saline prior to
> airway clearance. My current habit, which I often seem to be tweaking, is
> to soak in hot tapwater with some dawn after each use. At the end of the
> day, I sterilize it in the Bololo baby bottle sterilizer. This sterilizer
> along with others have been deemed effective by Dr. Jenn Honda. She
> presented not too long ago on use of baby bottle sterilizers for our
> equipment. I think her presentation can be found in the ABCs of
> bronchiectasis in this forum. Pari recommends the handset be replaced every
> six months.
>
> PS-here’s the presentation by Dr. Jenn Honda. Well worth watching.
> https://m.youtube.com/watch
> VIEW & REPLY
> < https://connect.mayoclinic.org/notification/84856872/;
> ------------------------------
> Unsubscribe
> < https://connect.mayoclinic.org/email/unsubscribe/email-setting/;
> from this content and see links to review my email settings.
>

REPLY

Spectrumcyclist. I purchased it in August and use it for sodium chloride and cromolyn sodium. Unfortunately I can use it only for 3% or mix of 3 and 7 because just 7% makes me cough really bad when I nebulize no matter what truck I do. But it is fast and quiet and you might be able to use it for your purposes of course.

REPLY
Profile picture for scoop @scoop

@minute22 I cannot answer the question regarding Arikayce because I’ve never used it. Twice a day I use the E flow with hypertonic saline prior to airway clearance. My current habit, which I often seem to be tweaking, is to soak in hot tapwater with some dawn after each use. At the end of the day, I sterilize it in the Bololo baby bottle sterilizer. This sterilizer along with others have been deemed effective by Dr. Jenn Honda. She presented not too long ago on use of baby bottle sterilizers for our equipment. I think her presentation can be found in the ABCs of bronchiectasis in this forum. Pari recommends the handset be replaced every six months.

PS-here’s the presentation by Dr. Jenn Honda. Well worth watching.
https://m.youtube.com/watch

Jump to this post

@scoop Hi Scoop, I noticed in the video that it was the “antibacterial” Dawn that killed NTM, not the regular 2% Dawn. When investigating this, I found that the “antibacterial” comes in Apple Blossom and Orange scents and are also used as ”hand soap” (which likely means there’s some kind of lotion in there). I imagine these are not great for the equipment or for our lungs. None of the other Dawn liquid dishwashing soaps are listed as “antibacterial “. There are, however, some clear, antibacterial “hand soaps” on the market, but wonder if those have the same NTM releasing qualities as the Dawn. I sent Dr. Honda an email, asking her to clarify what exactly they used in their experiments but have not heard back. I may reach out to Dr. Falkinham. Any thought on this?

REPLY
Please sign in or register to post a reply.