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ronniekep
@ronniekep

Posts: 4
Joined: Nov 02, 2018

Hyperhomocysteinemia with MTHFR C677T mutations. Does anyone have this

Posted by @ronniekep, Thu, Nov 8 6:48am

Hi, I took a DNA test to see what medications I could not take and while finding out, I would out I carry this gene. Does anyone else have this? I know I am not alone! I have raised my folate and B12 and B6 but I delay the response to antidepressants.

REPLY

Hello @ronniekep

Welcome to Mayo Connect! You have posted a very interesting topic, Hyperhomocysteinemia with MTHFR C677T mutations. While I have never heard of this before I did find some information on Mayo Clinic's website. Please click on the link and take a look at it, https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/81648

If you are comfortable sharing more about this discovery could you explain why the DNA test was done? Was it at your doctor's suggestion or something you did on your own? Were you having particular health problems that led you to do the DNA testing other than to discover what meds you could take or not?

@hopeful33250

Hello @ronniekep

Welcome to Mayo Connect! You have posted a very interesting topic, Hyperhomocysteinemia with MTHFR C677T mutations. While I have never heard of this before I did find some information on Mayo Clinic's website. Please click on the link and take a look at it, https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/81648

If you are comfortable sharing more about this discovery could you explain why the DNA test was done? Was it at your doctor's suggestion or something you did on your own? Were you having particular health problems that led you to do the DNA testing other than to discover what meds you could take or not?

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Hi,
I have Scleroderma and have been seeing a wonderful nutritionist who offers DNA testing as well as other labs. After seeing her for almost 3 years, she has helped me immensely with going Gluten Free and Dairy Free. I have made a complete lifestyle change due to her and started suffering depression in March 2018. I have been seeing a psychiatrist for slight anxiety and was taking Cymbalta 60mg, for anxiety, pain and migraines. In August the depression seemed to have gotten worse and realized maybe the Cymbalta was not doing its job. I decided to take the DNA test to find out Meds would work out best for me and then found out I carry this gene.

@ronniekep

Hi,
I have Scleroderma and have been seeing a wonderful nutritionist who offers DNA testing as well as other labs. After seeing her for almost 3 years, she has helped me immensely with going Gluten Free and Dairy Free. I have made a complete lifestyle change due to her and started suffering depression in March 2018. I have been seeing a psychiatrist for slight anxiety and was taking Cymbalta 60mg, for anxiety, pain and migraines. In August the depression seemed to have gotten worse and realized maybe the Cymbalta was not doing its job. I decided to take the DNA test to find out Meds would work out best for me and then found out I carry this gene.

Jump to this post

I appreciate you sharing your background, @ronniekep. I am glad to hear that the nutritionist has helped you with your Scleroderma. I know of friends who also have this disorder and it can be difficult to control.

If you had an opportunity to look at the Mayo website article, do you see any similarities to how you are feeling with some of the information provided there (or perhaps with a family member)?

Do you plan to do any other follow up as a result of this finding?

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