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GLP-1 Drugs Causing Arrythmias

Posted by larry @larryst, Dec 23, 2024

My cardiologist suggested I start taking a GLP-1 drug. I have read those could cause arrhythmias (my problem). Has anyone had any experience with GLP-1 drugs ?

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deniseheart | @deniseheart | Jan 20 6:30pm
In reply to @kpryor1982 "@deniseheart I’m on the lowest dose. .5" + (show)
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@deniseheart I’m on the lowest dose. .5

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@kpryor1982 thank you for your reply. I am on a lower dose, 2.5.

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kpryor1982 | @kpryor1982 | Jan 20 11:58pm
In reply to @deniseheart "@kpryor1982 thank you for your reply. I am on a lower dose, 2.5." + (show)
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@kpryor1982 thank you for your reply. I am on a lower dose, 2.5.

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@deniseheart maybe go down. I’ve lost 31 pounds in 6 weeks on the lowest dose possible. If you’re having bad pvcs. I’m still getting them on the lowest dose so I’m contemplating this being my last month on them. I don’t know. I need the weight loss and I may still have the pvcs after. I’ve had them a while. Just not this bad.

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deniseheart | @deniseheart | Jan 21 9:24am
In reply to @kpryor1982 "@deniseheart maybe go down. I’ve lost 31 pounds in 6 weeks on the lowest dose possible...." + (show)
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@deniseheart maybe go down. I’ve lost 31 pounds in 6 weeks on the lowest dose possible. If you’re having bad pvcs. I’m still getting them on the lowest dose so I’m contemplating this being my last month on them. I don’t know. I need the weight loss and I may still have the pvcs after. I’ve had them a while. Just not this bad.

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@kpryor1982 dosing for Tirzepatide is as follows: 2.5mg 5.mg 7.5mg 10mg. 12.5mg or 15mg. I am on the 2.5mg dose and all is well but no weight loss yet. I will give this dose another week to see if it kicks in. Very happy to know that you had great success on the 5.mg dosing.

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kpryor1982 | @kpryor1982 | Jan 22 12:18am

For mine (monjarro) they told me I’m on .5. And I draw up 50 in the syringe. So I don’t know. That’s just what my pcp showed me and said.

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kpryor1982 | @kpryor1982 | Jan 22 12:19am
In reply to @deniseheart "@kpryor1982 dosing for Tirzepatide is as follows: 2.5mg 5.mg 7.5mg 10mg. 12.5mg or 15mg. I am..." + (show)
Profile picture for deniseheart @deniseheart

@kpryor1982 dosing for Tirzepatide is as follows: 2.5mg 5.mg 7.5mg 10mg. 12.5mg or 15mg. I am on the 2.5mg dose and all is well but no weight loss yet. I will give this dose another week to see if it kicks in. Very happy to know that you had great success on the 5.mg dosing.

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@deniseheart I told him I don’t want to go up any. So I am going to ask him again what dose I’m on. Because I’m confused now

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daralassa | @daralassa | Jan 22 11:02am
In reply to @calson "I have been taking Ozempic for 6 months with no issues but have recently switch to..." + (show)
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I have been taking Ozempic for 6 months with no issues but have recently switch to Mounjaro which has been more effective for most. The GLP type drugs are the most likely to increase HDL and lower triglycerides and that is why they are good for heart health overall.

There are people having problems with the injectable GLP drugs are primarily those injecting into the stomach and not those injecting into an arm or leg.

I have switched most of my heart medications but sticking to the same type, as with the Metoprolol beta blocker that I switched to taking another beta blocker, Bisoprolol. I am switching from the statin rosuvastin to Lipitor as the former has a significant drug to drug interaction with Ticagrelor. I switched to Ticagrelor as Plavix/clopidogrel with rosuvastin increases the AUC by 2.5 fold.

With multiple drugs one is much more dependent on their cardiologist and this unfortunately is not a solution as doctors very seldom in my own experience are sufficiently diligent and tend to hope for the best.

I have needed to spend days doing the research on my own but as my life is important to me the effort is not something I would consider not doing.

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@calson "There are people having problems with the injectable GLP drugs are primarily those injecting into the stomach and not those injecting into an arm or leg." This is not true for me. I inject in the thigh, but still have the heart rate increase issues.

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deniseheart | @deniseheart | Jan 24 12:29pm
In reply to @kpryor1982 "For mine (monjarro) they told me I’m on .5. And I draw up 50 in the..." + (show)
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For mine (monjarro) they told me I’m on .5. And I draw up 50 in the syringe. So I don’t know. That’s just what my pcp showed me and said.

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@kpryor1982 I stand corrected. 0.5 ml is the lowest dose. 0.5ml and 2.5 mg is the same. Sorry for the confusion.

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snovathompson | @snovathompson | Feb 20 9:48am

I replied to a post regarding this back in August 2025. My husband stopped taking Ozempic after struggling with PVC, SVT and his defibrillator going off three times in 10 hours (for prior context, he had his defibrillator for six years and it never went off prior to this, and didn't have issues prior to this).
After discussing with cardiologist and PCP, he decided to go back on Ozempic about 6 weeks ago. He began having issues again last night.
I understand Ozempic is very beneficial for heart health, but this is very difficult to rationalize that Ozempic hasn't played a role in his recent issues. This is the only change in his medications/lifestyle.

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