GLP-1 Drugs Causing Arrythmias

Posted by larry @larryst, Dec 23, 2024

My cardiologist suggested I start taking a GLP-1 drug. I have read those could cause arrhythmias (my problem). Has anyone had any experience with GLP-1 drugs ?

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Profile picture for kim12345 @kim12345

For me, I had my first AFib episode 24 hours after I got my shot. Then had another episode the following week 24 hour after I took my shot of Zepbound. Maybe it was purely coincidence or the Zepbound brought it on. Now I'm on Eliquis and waiting for my cardiologist appointment. Holding off on the Zepbound for now. Super frustrating.

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@kim12345 make sure well hydrated and your electrolytes are well balanced .

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Profile picture for swex @swex

I started taking semaglutide about 5 months ago. During the last 30 days on semaglutide, GLP-1, my dosage was increased. I’ve lost about 20lbs on it. I had a history of Afib and 7 years ago had a heart ablation because I didn’t want to be on blood thinners and heart rate meds for the rest of my life. I’ve had no reoccurrence of Afib for 7 years. All of a sudden last month I went into persistent Afib. I went to urgent care and have spoken to a few doctors and no one seems to know anything about a relationship between GLP-1 and Afib. Everything on the internet says GLP-1 should actually help with AFIB because of weight loss. I stopped taking Semaglutide 2 weeks ago but am still in AFIB. I will be seeing a Mayo cardiologist in a few weeks.
Anyone else have any experience with GLP-1 and AFIB

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@swex not having AFIB problems, but my blood pressure has been running lower around 90/55.

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Profile picture for gloaming @gloaming

https://pmc.ncbi.nlm.nih.gov/articles/PMC9403613/
This very recent analysis suggests there is no causal link between GLP-1 agonist usage and cardiac arrhythmias.

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@gloaming I sincerely hope that this is true. I started Ozempic 6 weeks ago to hopefully help my heart failure issues as well as the need to lose some weight to improve my health status. It's been tough dealing with some of the side effects, but plan on continuing with the Qzempic.

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Profile picture for joyh @joyh

@gloaming I sincerely hope that this is true. I started Ozempic 6 weeks ago to hopefully help my heart failure issues as well as the need to lose some weight to improve my health status. It's been tough dealing with some of the side effects, but plan on continuing with the Qzempic.

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@joyh We both hope I'm right, Joy, but I hope we both continue to keep our ear to the ground. Science, and it's advice-givers, tend to be highly mobile these years about the latest advice and findings, and I try hard to watch a variety of videos from different 'influencers' and read a variety of sources to ensure I can paint myself a reasonable ...and safe...prescription for me to keep following or to change to. In case it's news to you, was to me until about 10 months ago, some people develop moderate to severe problems, side-effects, to a drug used to reduce the risk of stroke in people with atrial fibrillation, one I take called Eliquis. I initially responded that it was well tolerated by pretty much everyone and that I had never heard of leg and muscle pain, or whatever the purported link the asker was proposing. Turns out I was wrong, and had several posters correcting me! Some people cannot take apixaban and still feel like living. I hope it's not true for you and Ozempic.

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Profile picture for gloaming @gloaming

@joyh We both hope I'm right, Joy, but I hope we both continue to keep our ear to the ground. Science, and it's advice-givers, tend to be highly mobile these years about the latest advice and findings, and I try hard to watch a variety of videos from different 'influencers' and read a variety of sources to ensure I can paint myself a reasonable ...and safe...prescription for me to keep following or to change to. In case it's news to you, was to me until about 10 months ago, some people develop moderate to severe problems, side-effects, to a drug used to reduce the risk of stroke in people with atrial fibrillation, one I take called Eliquis. I initially responded that it was well tolerated by pretty much everyone and that I had never heard of leg and muscle pain, or whatever the purported link the asker was proposing. Turns out I was wrong, and had several posters correcting me! Some people cannot take apixaban and still feel like living. I hope it's not true for you and Ozempic.

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@gloaming thanks so much for your info!

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