Just approved: Evusheld for the pre-exposure prevention of COVID-19

Congratulations @lizzy102 on your success getting Evusheld! That's awesome news 😊
I am curious what type of location and (which state) is saying they have "tons of Evusheld". Was it a hospital, small clinic, pharmacy, etc?
I can't believe that the top transplant and cancer hospitals are having a problem getting meaningful inventory of the shot. Aren't you shocked that Mayo is not well-stocked and your location has tons of it? I think the federal government distributed the treatments to the states and left it up to the state to distribute to locations. I think that may be why the patient process and availability is differing so much from state to state.

At this point, my understanding is that Evusheld was distributed to the states. The states then pass the medication on to infusion centers based on Rx orders from doctors (who are qualified to assert that X person is properly immunocompromised). The infusion center I went to (in a hospital) had received 15 Rx and patients for the shots, entirely since the med was first distributed. They said they have no problem accessing the medication and that they have been surprised that more doctors/patients are not requesting the protocol.
No matter what any given hospital/medical center says to patients, the doctors have had to struggle with their own beliefs about this medication, their own prejudices and worries about rejection of organs with stronger immune responses etc. I can say that it took several months of being a very squeaky wheel to get my medical team to send the Rx out. I heard lots of reasons why I would not be able to get the medication from them - mostly having to do with not being a recent transplant recipient. Then suddenly, the Rx was sent, the infusion center received, the shots scheduled and I walked out the door with two bandaids on my glutes.

Hi @lizzy102 😊
Yeah! I am so happy that all your hard work advocating for yourself was FINALLY successful and you received Evusheld (two band-aids!) . You are proof that it's important for us all to advocate for our own health. Thank you for sharing your success story!

Hi there, wondering if you ended up getting evusheld. What type of autoimmune neuro. I have auroimmune neuro disease that flared bad to mrna. Used to do ok with ivig. Then started flaring to it. Trying to decide on Evusheld but only have one vax in me

@missmissyb, I want to welcome you to Connect. I am a transplant recipient. I was notified by my transplant department in May that I was determined to be eligible for Evusheld. I was given information to help me make my decision. After reading the information that I am sharing here, I decided to get the Evusheld during my annual evaluation appointment at Mayo in May. I want to share the information with you.

Here is a statement that I have copied from the CDC website about Evusheld.
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If your body does not mount a strong enough immune response to COVID-19 vaccination, you have another option to help your body build more protection. Evusheld is a medicine containing antibodies that can help prevent you from getting COVID-19.

Evusheld is authorized as pre-exposure prophylaxis (PrEP) for prevention of COVID-19. It is given before you get exposed or test positive to help prevent COVID-19 infection. Evusheld is not used to treat COVID-19 symptoms. It is also not a substitute for COVID-19 vaccination.

You may be eligible for Evusheld if you:

Are moderately or severely immunocompromised (see list above) OR have a history of severe allergic reactions to COVID-19 vaccines, and
Do not currently have COVID-19 and have not recently had close contact with someone with COVID-19, and
Are an adult or adolescent ages 12 years and older weighing at least 88 pounds (40 kg)
Your healthcare provider will determine if you are eligible for Evusheld. You will need to go to a provider’s office to get it. Talk to your healthcare provider about whether you should get Evusheld in addition to COVID-19 vaccination.
- https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/people-who-are-immunocompromised.html
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- Evusheld EUA Fact Sheet for Patients, Parents and Caregivers
https://www.fda.gov/media/154702/download

MissMissy, I was current with all of my current with my Covid vaccines and had my 1st booster. I was due for my 2nd booster at the same time as my Evusheld, and so I had to delay that for 2 weeks.
Has your doctor suggested Evusheld for you?

Thank you for responding. Yes the neurologist thought it might be a better option than more mrna doses and ordered it (up to me).. I would also want to get the antiviral.. I am glad for you and anyone that could tolerate and then benefit. You dont have autoimmune neuro disease right? Ive only see a few people on here with autoimmune neuro disease, people like me who have severe “take downs” to vaccine and virus on here. Looking to discuss that specifically. Concerned that I could potentially flare worse and linger to Evusheld. Found case study of person who previously had Guianne-Barre response to mrna (simmilar to my responses) but this person did ok with the Evusheld so that was reassuring along with me having done mostly ok with ivig for some years.

I haven't gotten Evusheld. My autoimmune issue coincided with my neurological damage and symptoms after the Pfizer vaccine. When my symptoms peaked, my ANA titer peaked. I also have Sjögren’s B autoantibody, but don't have Sjögren’s. Like most vaccine-injured people, my autoimmune profile doesn't fit into the available autoimmune diagnoses. That's likely because a toxic autoimmune reaction to the spike protein encoded by the vaccines has not happened before; this is new technology. The patients with neurological injuries in the Neuro V Long-Haulers Facebook group don't know what to do about Evusheld. I searched the posts last night and there were no reports of harm, but only two reports of using Evusheld, and those were initially positive experiences. I'm being cautious because Evusheld is another emergency use authorization. As another Mayo Connect patient indicated, you can read the Fact Sheet here. I'm concerned about the repeated emphasis in the document that Evusheld is unapproved by the FDA. https://www.fda.gov/drugs/drug-safety-and-availability/fda-authorizes-revisions-evusheld-dosing

Thank you!

I was able to get my Evushield shots about two weeks ago. My GP ordered them for me and was told at my 4 year transplant checkup that it would be a good thing. I had told my Mayo provider that I had gotten a letter from Allina saying that I was eligible. Got them at a hospital in the glutes also and had no side effects. Yay!

@cmael, So you got your local health care provider. That sounds great! I was lucky about the perfect timing of my notice with my Mayo Clinic visit! I had been deciding whether to get my 2nd booster before or after my annual post transplant visit and if the notice in my Mayo Patient Portal had come a day later, I might have had the booster which would have disqualified me for the Evusheld. Timing IS everything. I have an appointment with PCP tomorrow, and will ask him about the possibility of getting the next Evusheld locally if one is recommended. I won't be at Mayo until next May.
I'm always happy to see your name pop up! I still remember meeting you in the lab waiting area.