Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Hello. Could you please explain more about the side effects that you experienced when you started on this medication? I have experienced so many negative side effects from medications and I am worried about adding one that could make me feel worse for a few weeks, Thank you.

This medication can be used for several medical issues. I take it for Fibromyalgia. You have to get online and make sure your medications don't interact with others. I have taken it for three years, started at 90 milligrams and titrated to 60 per day. When trying to quit my Fibro came back horribly. Yes, this medication works for me, I don't have any side affects. Good luck.

I share your concern. I have the bottle of meds in my cabinet. I’m preparing to start it. Dreading it….but I have to try it, before my insurance will cover Lyrica.
And, Cymbalta may actually serve me better. Idk.

I’m ambivalent. I’ve read so much about it. Different people have different experiences. What I know is that my intermittent burning is excruciating and I can’t tolerate it long term. I’m scared and looking for answers, since my only diagnosis right now is Vitamin B12 deficiency.

Klonapin does help, but that’s a short term thing. If my burning continues, I’ll need something daily. I wish there was something to take on as as need basis, that’s not a Benzo, since I feel great on days there isn’t burning.

When do you think you’ll start and what symptoms did you have trouble with?

Hi! I’ve been on Duloxatine since 2016. It helped immediately with pain. Also with depression and anxiety. I take 90 mg during winter and 60 spring summer. I am having some fatigue now. Not sure 🤔 f due to the 90 mg. It has helped me. Goodluck

Cymbalta did help my pain and overall that was great...but it did make me feel weird. Can't really describe it. However I have issues with constipation and after 5 days of having no bowel movement I stopped it (took a Dulcolax with my daily stool softener and 'amatiza). I went 9 days after my TKR and was backed up to my distal colon so this was not an option for me. I only took 20mg then tried 10mg. Still a no go. I do take 900mg Gabapentin at bedtime and that is well tolerated. I have to be careful with any Nsaids as well and Cox 2 inhibitors which I don't really take. Best of luck. It's hard when the options are so limited.

I was prescribed Cymbalta for nerve pain by a new doctor in an attempt to get me off Tramadol which I have taken since like 2012 for severe spondylolithsesis. I am extremely mindful of what I put in my mouth and do not have an addictive personality. This doctor accused me of being a drug addict - then he looked at my X-rays and realized he was mistaken and prescribed the tramadol.( I am unable at this point to have surgery due to lung issues.) I had already picked up the Cymbalta at the pharmacy . It really is a helpful drug for overall mood and pain relief. You could try it and see if it helps you. If you don’t see an improvement stop it by tapering off gradually and you should be fine. I was able to get a “right for me”doctor with the help of my old pcp who went into ID at the local hospital here. Doctors need to listen to their patients. Really listen. You can’t take Cymbalta with tramadol so if you do start it make sure you know what it might interact with- your pharmacist should tell you. You have to advocate for yourself, and it is hard sometimes with the new government rules. Older people are especially being impacted as I think we want quality of life as we age and sometimes that is just darn hard when you have chronic pain. Both my husband and I lost our wonderful pcp in June. I finally have recently found someone for him. He has many health issues and losing a pcp then needing meds before his far out (February appointment with the new pcp ) has been a nightmare. Wishing you good luck. Irene5

@irene5 I looked up interactions between Cymbalta and Tramadol on Drugs.com and there are people with certain conditions who cannot take the two drugs together and your doctor will know if you fall within that group. However, I take the two drugs with no side effects.