Live vs inactivated COVID vaccine for transplant patients?

Posted by jerrynord @jerrynord, Aug 16, 2020

I have heard some discussion about transplants should not be getting a "live" vaccine when it becomes available for Covid-19. I think MAYO should come out with a statement if this is true or false.

Interested in more discussions like this? Go to the Transplants Support Group.

Thanks, Jerry for starting this new discussion to pick up where you, @tjgisewhite @estrada53 @rosemarya @danab @ca426 @contentandwell and few others went on a tangential side conversation about the development of a COVID-19 vaccine in the shingles vaccine discussion here:
https://connect.mayoclinic.org/discussion/shingles-vaccine-1/?pg=2#comment-416053

@rosemarya is right. It's too early to know.

From Mayo Clinic
"Global health authorities and vaccine developers are currently partnering to support the technology needed to produce vaccines. Some approaches have been used before to create vaccines, but some are still quite new.
- Live vaccines
- Inactivated vaccines
- Genetically engineered vaccines
Read more details here: https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-vaccine/art-20484859

We are still months away from having a vaccine and several successful vaccines will be needed to provide coverage for the country and worldwide. Once we have a vaccine, Mayo Clinic will certainly provide guidance to transplant recipients.

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I recommend following Mayo Clinic podcasts https://connect.mayoclinic.org/page/podcasts/tab/newsfeed/ to stay up to date with COVID related information from Mayo Clinic experts. Here are a couple of episodes related to this topic:
- Herd immunity, antibodies and COVID-19 https://connect.mayoclinic.org/page/podcasts/newsfeed-post/herd-immunity-antibodies-and-covid-19/
- COVID-19 update with vaccine expert Dr. Gregory Poland: vaccine trials and unique COVID symptoms https://connect.mayoclinic.org/page/podcasts/newsfeed-post/covid-19-update-with-vaccine-expert-dr-gregory-poland/

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Here's a July update from Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic’s Vaccine Research Group. He talks about the progress towards a vaccine for COVID-19, discusses therapies for treating the virus and shares research on how effective face masks and physical distancing are in fighting the spread of the disease.

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@colleenyoung

Thanks, Jerry for starting this new discussion to pick up where you, @tjgisewhite @estrada53 @rosemarya @danab @ca426 @contentandwell and few others went on a tangential side conversation about the development of a COVID-19 vaccine in the shingles vaccine discussion here:
https://connect.mayoclinic.org/discussion/shingles-vaccine-1/?pg=2#comment-416053

@rosemarya is right. It's too early to know.

From Mayo Clinic
"Global health authorities and vaccine developers are currently partnering to support the technology needed to produce vaccines. Some approaches have been used before to create vaccines, but some are still quite new.
- Live vaccines
- Inactivated vaccines
- Genetically engineered vaccines
Read more details here: https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-vaccine/art-20484859

We are still months away from having a vaccine and several successful vaccines will be needed to provide coverage for the country and worldwide. Once we have a vaccine, Mayo Clinic will certainly provide guidance to transplant recipients.

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@colleenyoung This is exactly right, it is premature to try to figure this out. We need to wait to see what will be available. I have to admit though, I am concerned it will be a live vaccine and not an option for those of us on immunosuppressants.

Looking forward to reading those links you sent, too late now. 😴
JK

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The vaccine for COVID-19, is different than any other vaccine, in that its a mRNA vaccine, never been used before. I would be cautious about this on, mRNA vaccine's haven't been used before. There's a couple of articles the New England Journal of Medicine, I would recommend reading , just do a search on their main page.

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