B-6 vitamin danger!

Posted by Lynsorensen @lynsorensen, Dec 11, 2017

With the assistance of a neurologist at Mayo Clinic, I have almost completely eliminated the uncontrolled muscle spasms now. First and foremost: beware of taking multi-vitamin capsules that have B6 listed. B-6 overdosage (which is contained in every multivitamin I found in stores and on the internet) can cause loss of muscle control and spasms in some people. So can gluten found in many foods so now I am also gluten free. I now work out with a personal trainer 3 days a week and do water aerobics another 2 days. Got off gabapentin and also clonazepam. Using CBD oil capsules each morning (no more opioids or chemicals) and using a CBD topical ointment to rub on my leg muscles each night. He says I don’t need him anymore! And I don’t. No more shaking or muscle cramps or pain. Still a little numbness but that is receding also.

@linnythepoo

Yikes! My oncologist prescribed 100 mg of vit B6 for my neuropathy! Has anyone heard of it helping neuropathy?

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This is so crazy to hear about. Just last week my neurologist told me B6 causes neuropathy. So why are our oncologist feeding it to us like candy. It is crazy. Rb6 level should be 125 or less! I just had mine done they just do a blood test and mine was 292.8 no wonder my feet are falling off

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This B6 thing seems to be appearing more and more. I am curious if it is because the body is not metabolizing B6 properly in some cases. When it comes to supplements many physicians are not well educated. My primary had bloodwork done and my B12 levels were a little high. She freaked. I also had a cholesterol check and had eaten only lentils the day prior.
I think for the most part a healthy diet is the key barring health issues preventing thus.
Off topic but the correct vitamin group.

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Hello @suzzangel02, welcome to Mayo Clinic Connect. There is a lot of information available about vitamin B6 toxicity. Here's one of the sites I've found that provides a good explanation.

Vitamin B6 Toxicity
https://www.easy-immune-health.com/vitamin-b6-toxicity.html

John

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@johnbishop

@lynsorensen that’s great news. Lots of info on B6 toxicity out there. This is one of the better sites I’ve found that puts it all together in an easy to understand way.

Vitamin B6 Toxicity:
http://www.easy-immune-health.com/vitamin-b6-toxicity.html
John

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Hi John I'm new to this recently diagnosed with prepheral neuropathy, don't know how to start a discussion on here.

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I'm new to this site…. found it by googling neuropathy. I have always had mild numbness in my toes on both feet, however, it seems to have really escalated in the past 3 months. Had an MRI of lumbar and sacral spine that has not shown any nerve impingement. I have been racking my brain to figure out what I am doing that is different. The only thing I can think of is starting B6 vitamins. My daily dose is about 6-8 MG. Could B6 be the culprit?

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@vcranford

I'm new to this site…. found it by googling neuropathy. I have always had mild numbness in my toes on both feet, however, it seems to have really escalated in the past 3 months. Had an MRI of lumbar and sacral spine that has not shown any nerve impingement. I have been racking my brain to figure out what I am doing that is different. The only thing I can think of is starting B6 vitamins. My daily dose is about 6-8 MG. Could B6 be the culprit?

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Hello @vcranford — welcome to Mayo Clinic Connect. From the research I've done vitamin B6 is different from the other B vitamins in the way the body absorbs and gets rid of it. Too much is definitely a bad thing. Here are a few sites that discuss B6 induced neuropathy.

NIH – Nutritional Neuropathies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/

Vitamin B6 Toxicity Revisited: A Case of Reversible Pyridoxine-associated Neuropathy and Disequilibrium. (P4.021)
http://n.neurology.org/content/90/15_Supplement/P4.021

Have you been diagnosed with neuropathy? I have idiopathic small fiber PN with only numbness as a symptom. I went over 20 years before getting a diagnosis, mainly because the doctor told me there's not much they can do. Then I decided to start being my own advocate and research of treatments. Still haven't found much that helps with just numbness.

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@vcranford

I'm new to this site…. found it by googling neuropathy. I have always had mild numbness in my toes on both feet, however, it seems to have really escalated in the past 3 months. Had an MRI of lumbar and sacral spine that has not shown any nerve impingement. I have been racking my brain to figure out what I am doing that is different. The only thing I can think of is starting B6 vitamins. My daily dose is about 6-8 MG. Could B6 be the culprit?

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@vcranford Not likely at that small dose of B6.

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I've been dealing with B6 toxicity for 6 months now. Levels were at 190 for a range of 20-125. I was taking a 100 mg supplement for about 2 months when I started noticing tingling in my upper back. I had my B6 levels tested right after I learned about B6 toxicity. The levels came down very quickly but I was left with the same tingling in back and fingers, muscle twitches, joint pain (mostly in fingers), and brain fog with other random symptoms that come and go rather quickly. This has been a nightmare! Has anyone had similar symptoms and improved or found relief? Doctors have not been much help as they don't seem to educated about the effects of B6. I've read most everything I can find on the internet, but stumbled across this thread today. Not even sure if the discussion is still going or if someone can point me to another discussion?

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@moodyfamily6

I've been dealing with B6 toxicity for 6 months now. Levels were at 190 for a range of 20-125. I was taking a 100 mg supplement for about 2 months when I started noticing tingling in my upper back. I had my B6 levels tested right after I learned about B6 toxicity. The levels came down very quickly but I was left with the same tingling in back and fingers, muscle twitches, joint pain (mostly in fingers), and brain fog with other random symptoms that come and go rather quickly. This has been a nightmare! Has anyone had similar symptoms and improved or found relief? Doctors have not been much help as they don't seem to educated about the effects of B6. I've read most everything I can find on the internet, but stumbled across this thread today. Not even sure if the discussion is still going or if someone can point me to another discussion?

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Hi @moodyfamily6, welcome to Mayo Clinic Connect. This discussion is still fairly active. If you go to the top below the discussion description and click the Newest to Oldest you will see the newest posts at the top. I don't have B6 toxicity but here is some information that may help.

Vitamin B6 Toxicity
http://www.easy-immune-health.com/vitamin-b6-toxicity.html
B Vitamins for Neuropathy and Neuropathic Pain
https://www.omicsonline.org/open-access/b-vitamins-for-neuropathy-and-neuropathic-pain-2376-1318-1000161.php?aid=90896
B6 section it explains — too much or too little gives neuropathy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/
FDA Safety Alert: Biotin Can Affect Medical Test Results
http://cle.clinic/2G6Mp4y
NIH – Nutritional Neuropathies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/

Vitamin B6 Toxicity Revisited: A Case of Reversible Pyridoxine-associated Neuropathy and Disequilibrium. (P4.021)
http://n.neurology.org/content/90/15_Supplement/P4.021

Are you still taking any supplements?

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No, I stopped a couple of days ago

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@johnbishop

Hi @moodyfamily6, welcome to Mayo Clinic Connect. This discussion is still fairly active. If you go to the top below the discussion description and click the Newest to Oldest you will see the newest posts at the top. I don't have B6 toxicity but here is some information that may help.

Vitamin B6 Toxicity
http://www.easy-immune-health.com/vitamin-b6-toxicity.html
B Vitamins for Neuropathy and Neuropathic Pain
https://www.omicsonline.org/open-access/b-vitamins-for-neuropathy-and-neuropathic-pain-2376-1318-1000161.php?aid=90896
B6 section it explains — too much or too little gives neuropathy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/
FDA Safety Alert: Biotin Can Affect Medical Test Results
http://cle.clinic/2G6Mp4y
NIH – Nutritional Neuropathies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/

Vitamin B6 Toxicity Revisited: A Case of Reversible Pyridoxine-associated Neuropathy and Disequilibrium. (P4.021)
http://n.neurology.org/content/90/15_Supplement/P4.021

Are you still taking any supplements?

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No, I stopped the supplements 6 months ago. Definitely won’t be taking them again. Thank you for these links!

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My doctor told me to take B12. Is it toxic too?

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