New Study on Post-COVID Syndrome

Apr 27, 2021 | Greg Vanichkachorn | @drvan | Comments (12)

As we learn more about Post COVID Syndrome and Post-Acute Sequelae of SARS-COV2, there are growing concerns that the symptoms patients are experiencing are due to a neurological problem. Headache, dizziness, rapid heart rate, muscle, and chest pain; all of these could be related to how the nerves in our body are functioning.  Specifically, there have been reports of autonomic dysfunction.

The autonomic nervous system is what controls all the things in our body that we aren’t normally thinking about, like our pulse and intestine movement. To understand this better, researchers at Mayo Clinic looked at the patients we have seen for PASC and PCS to see if there are any indications of autonomic dysfunction, and the results of this analysis were recently published.

 

27 patients showed signs of possible autonomic dysfunction between March 2020 and January 2021.  The most common symptom was lightheadedness and headache.  Some patients also experienced sweating, burning pain, and syncope (passing out). On testing, one fifth of patients met criteria for a diagnosis of postural tachycardia syndrome (POTS), a specific form of autonomic dysfunction. Other abnormalities were found less frequently, including worsening of preexisting orthostatic hypotension (dizziness on standing) and small fiber neuropathy (causes diffuse pain).

 

Overall, our study shows that patients with PSC or PASC can have symptoms from autonomic dysfunction, and that these problems are sometimes detected on testing. While this finding is not enough to say that COVID-19 infection causes autonomic nerve problems, it emphasizes the need for more research in this area and for patients to report such symptoms to their providers.

Stay tuned to our Research page as we learn more about Post-COVID Syndrome and PASC. Discuss this study and more in the discussion group.

Interested in more newsfeed posts like this? Go to the Post-COVID Recovery blog.

@stoneydintheloo

I didn't have any of the symptoms I mentioned prior to my covid infection. Keeping a journal of my symptoms is a good idea. I don't really notice my chronic pain symptoms unless I'm actively working. I'm currently on a leave of abscense until I can learn what's causing my chronic foot and joint pain. I have an appointment with a podiatrist may 6th, but I feel like my foot along with my joint pain has a neurological connection or something that's increasing my inflammation. I work a very active job in warehousing that consists of 15 miles of fast paced walking along with lifting and stacking 2 to 3k boxes, many as heavy as 50lbs or more. Before covid i could do this job without issue. Since covid it's been 8 to 10 hours of suffering. I love being active and don't want to return to a lower paying desk job so I'm hoping to get answers from this group along with various Facebook covid long hauler groups I'm a member of. I hope my hematologist will also provide some answers as most of what I've learned is purely anecdotal.

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Hello @stoneydintheloo and welcome to Mayo Clinic Connect. As @colleenyoung mentioned, keeping a journal can be so helpful when tracking symptoms and changes. I am sorry to hear of the way this has affected you and your ability to do your job.

How have you been coping with the pain during your shift?

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@amandajro

Hello @stoneydintheloo and welcome to Mayo Clinic Connect. As @colleenyoung mentioned, keeping a journal can be so helpful when tracking symptoms and changes. I am sorry to hear of the way this has affected you and your ability to do your job.

How have you been coping with the pain during your shift?

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I was taking nsaids daily until my stomach started to reject them. I'm out on disability until I can find a way to treat the pain. I also have issues with post exercise chronic fatigue to which my job is nearly impossible since it consists of a very high level of physical exertion. An 8 hour day consists of 15 miles of fast paced walking along with lifting and stacking 2 to 3k boxes many as heavy as 60lbs. We are very understaffed so we're forced into 10 to 12 hour shifts along with forced overtime on our days off. I love the job and could do it without issues prior to covid. I don't want to leave the company for a lower paying office job but fear I may have no choice if my disability runs out before I find treatment for this long covid nightmare.

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