Glucose Issues

Posted by packh1 @packh1, Jul 26 10:52am

I am enjoying reading posts from everyone on various issue. Just wondering if anyone can relate to my problem. I have had prediabetic A1C results for several years. My GP has never been concerned and neither have I.4 months ago I was put on metoprolol, Jardiance and spironolactone for VTACH .My fasting glucose level skyrocketed and my A1C went form low 6 (6.1,6.2) to 6.8.This is in the 4 month period of being on these drugs. Seems suspicious to me. Cardiologist says it is not the meds.I am not overweight (5'6"-128lb),walk two to three miles daily and eat a well-balanced diet .It is discouraging to now be dealing with this on top of the heart issue. Having an ablation in two weeks.Hoping I can get off of most meds 3 months down the line.Just curious if anyone else can relate.Thank you all for being here .

Interested in more discussions like this? Go to the Heart Rhythm Conditions Support Group.

Profile picture for sjm46 @sjm46

I am a retired nurse who looks up everything that concerns my health and that of my husband. I do not take anything for absolute truth when it comes to someone saying "don't worry about it" when nobody knows your body better than you. So I did a brief AI search on Jardiance--which I highly suspect could be the problem since I have heard of adverse reactions to this "magic" weight loss drug. "Jardiance is designed to lower blood glucose levels, but in some cases, it may lead to a condition called euglycemic diabetic ketoacidosis, where blood glucose levels can be normal or even elevated despite the medication. It is important to monitor blood sugar levels regularly while on this medication." This is just one resource that I am sharing and I am not saying that this is what you are experiencing , but there are other resources online. Everyone is different; we are not all the same in our reaction to medications. You don't mention how old you are, but "pre-diabetic" is now the new BS diagnosis for everyone over 65 in my opinion. My husband got that diagnosis too and we take his blood gluscose level every week and it is never over 100, which is just the high level of "normal" according to the guidelines. He's 80 years old! If I were you, I would talk to your PCP or seek an opinion from your pharmacist regarding whether the medications you are on could be the culprit for the elevation. Cardiologists are not experts in every area of medication interactions. I remember my orthopedic surgeon telling me, when I asked for nerve pain relief at night from a fracture of the upper humerus, "I don't do pain management; I am a surgeon." This is the honest truth! I finally got him to begrudgingly give me a prescription for Amitriptyline, which is the gold standard treatment for nerve pain but "off label" use. Years ago, a neurologist told me about this when I had a severe dislocation of shoulder. My point is, there is something going on and you are correct to ask and be concerned. BTW: Good luck with the ablation; I had one in November of last year and the results have been great. Best wishes!

Jump to this post

@sjm46 "..."pre-diabetic" is now the new BS diagnosis for everyone over 65..."

I agree completely.

"There's nothing wrong with you that costly treatment won't prolong," as Monty Python said more than fifty years ago...

REPLY
Profile picture for Scott R L @scottrl

@sjm46 "..."pre-diabetic" is now the new BS diagnosis for everyone over 65..."

I agree completely.

"There's nothing wrong with you that costly treatment won't prolong," as Monty Python said more than fifty years ago...

Jump to this post

@scottrl That is so funny! I hadn't heard that before but it is so true! Thanks for the good laugh of the day! BTW: my husband also has COPD as a diagnosis--he has absolutely none of the symptoms of COPD except for a low blood oxygen level of 94. He's had it for years! Was a smoker--40 years ago! 🙂

REPLY
Profile picture for sjm46 @sjm46

I am a retired nurse who looks up everything that concerns my health and that of my husband. I do not take anything for absolute truth when it comes to someone saying "don't worry about it" when nobody knows your body better than you. So I did a brief AI search on Jardiance--which I highly suspect could be the problem since I have heard of adverse reactions to this "magic" weight loss drug. "Jardiance is designed to lower blood glucose levels, but in some cases, it may lead to a condition called euglycemic diabetic ketoacidosis, where blood glucose levels can be normal or even elevated despite the medication. It is important to monitor blood sugar levels regularly while on this medication." This is just one resource that I am sharing and I am not saying that this is what you are experiencing , but there are other resources online. Everyone is different; we are not all the same in our reaction to medications. You don't mention how old you are, but "pre-diabetic" is now the new BS diagnosis for everyone over 65 in my opinion. My husband got that diagnosis too and we take his blood gluscose level every week and it is never over 100, which is just the high level of "normal" according to the guidelines. He's 80 years old! If I were you, I would talk to your PCP or seek an opinion from your pharmacist regarding whether the medications you are on could be the culprit for the elevation. Cardiologists are not experts in every area of medication interactions. I remember my orthopedic surgeon telling me, when I asked for nerve pain relief at night from a fracture of the upper humerus, "I don't do pain management; I am a surgeon." This is the honest truth! I finally got him to begrudgingly give me a prescription for Amitriptyline, which is the gold standard treatment for nerve pain but "off label" use. Years ago, a neurologist told me about this when I had a severe dislocation of shoulder. My point is, there is something going on and you are correct to ask and be concerned. BTW: Good luck with the ablation; I had one in November of last year and the results have been great. Best wishes!

Jump to this post

@sjm46 Thank you for your informative and helpful post.I agree with you on all your points. I do have an appt set to meet with an endocrinologist but will check with my pharmacist like you recommended.I am in my 70s and my primary told me my numbers (lows6s)are considered diabetic but she didn't.She is surprised at my high numbers and suspects it could be meds .Since the meds are not prescribed by her she is deferring to the cardiologist.I am a cancer and when I was first diagnosed a cancer surgeon told me to always advocate for myself and be a partner with my drs. in my healthcare.

REPLY

AI Overview Metoprolol use is associated with a mildly increased risk of new-onset type 2 diabetes, reduced insulin sensitivity, and elevated fasting blood glucose levels. These metabolic changes occur because the medication can decrease glucose uptake in muscles and influence how the body handles insulin.How Metoprolol Affects Blood SugarLower insulin sensitivity: Body cells may not respond as well to insulin, making it harder to move sugar from the blood into the cells.Higher fasting glucose: Long-term use can lead to small increases in resting blood sugar and insulin levels.Masked low blood sugar signs: Beta-blockers can hide warning signs like a fast heartbeat during low blood sugar, though sweating usually remains unaffected.Managing the RiskMonitor levels: Regular blood glucose or HbA1c checks help catch upward trends early if you take metoprolol.Weigh benefits and risks: For heart conditions like heart failure or high blood pressure, the heart-protective benefits of beta-blockers often outweigh the metabolic risks.Talk to a doctor: Never stop taking a heart medication without medical advice; alternative treatments or lifestyle adjustments can help manage blood sugar.

REPLY
Profile picture for vjs003 @vjs003

AI Overview Metoprolol use is associated with a mildly increased risk of new-onset type 2 diabetes, reduced insulin sensitivity, and elevated fasting blood glucose levels. These metabolic changes occur because the medication can decrease glucose uptake in muscles and influence how the body handles insulin.How Metoprolol Affects Blood SugarLower insulin sensitivity: Body cells may not respond as well to insulin, making it harder to move sugar from the blood into the cells.Higher fasting glucose: Long-term use can lead to small increases in resting blood sugar and insulin levels.Masked low blood sugar signs: Beta-blockers can hide warning signs like a fast heartbeat during low blood sugar, though sweating usually remains unaffected.Managing the RiskMonitor levels: Regular blood glucose or HbA1c checks help catch upward trends early if you take metoprolol.Weigh benefits and risks: For heart conditions like heart failure or high blood pressure, the heart-protective benefits of beta-blockers often outweigh the metabolic risks.Talk to a doctor: Never stop taking a heart medication without medical advice; alternative treatments or lifestyle adjustments can help manage blood sugar.

Jump to this post

@vjs003 Thank you for the informative, helpful response.

REPLY
Profile picture for packh1 @packh1

@sjm46 Thank you for your informative and helpful post.I agree with you on all your points. I do have an appt set to meet with an endocrinologist but will check with my pharmacist like you recommended.I am in my 70s and my primary told me my numbers (lows6s)are considered diabetic but she didn't.She is surprised at my high numbers and suspects it could be meds .Since the meds are not prescribed by her she is deferring to the cardiologist.I am a cancer and when I was first diagnosed a cancer surgeon told me to always advocate for myself and be a partner with my drs. in my healthcare.

Jump to this post

@packh1
Hi Follow up. My pharmacist said Jardiance could be causing my high glucose and A1C readings.
Now on to meeting with an endocrinologist to see what they think. My cardiologist doesn't want me to stop taking it .It is expensive and if it is messing with my metabolism that concerns me.

REPLY
Profile picture for packh1 @packh1

@packh1
Hi Follow up. My pharmacist said Jardiance could be causing my high glucose and A1C readings.
Now on to meeting with an endocrinologist to see what they think. My cardiologist doesn't want me to stop taking it .It is expensive and if it is messing with my metabolism that concerns me.

Jump to this post

@packh1 , I’m trying to figure out why anyone would suspect Jardiance would cause increased blood sugar. Did they say why? Hopefully, the endocrinologist can evaluate your situation. I hope they can evaluate to confirm the cause of the high blood sugar…..is your body producing enough insulin or is your body not utilizing what it has? If you’re not producing enough insulin, then the Jardiance wouldn’t help much. Insulin is the primary thing to lower blood sugar, besides some GLP1 meds. I’ll look forward to seeing what you discover.

REPLY
Profile picture for celia16 @celia16

@packh1 , I’m trying to figure out why anyone would suspect Jardiance would cause increased blood sugar. Did they say why? Hopefully, the endocrinologist can evaluate your situation. I hope they can evaluate to confirm the cause of the high blood sugar…..is your body producing enough insulin or is your body not utilizing what it has? If you’re not producing enough insulin, then the Jardiance wouldn’t help much. Insulin is the primary thing to lower blood sugar, besides some GLP1 meds. I’ll look forward to seeing what you discover.

Jump to this post

@celia16 Hi,Good question.The pharmacist said in some cases it can cause the fluctuations. He wasn't clear as to why.so i am still confused and hoping an endocrinologist can set me straight.Of course getting an appt takes months.

REPLY
Please sign in or register to post a reply.