Glucose Issues

Posted by packh1 @packh1, 3 days ago

I am enjoying reading posts from everyone on various issue. Just wondering if anyone can relate to my problem. I have had prediabetic A1C results for several years. My GP has never been concerned and neither have I.4 months ago I was put on metoprolol, Jardiance and spironolactone for VTACH .My fasting glucose level skyrocketed and my A1C went form low 6 (6.1,6.2) to 6.8.This is in the 4 month period of being on these drugs. Seems suspicious to me. Cardiologist says it is not the meds.I am not overweight (5'6"-128lb),walk two to three miles daily and eat a well-balanced diet .It is discouraging to now be dealing with this on top of the heart issue. Having an ablation in two weeks.Hoping I can get off of most meds 3 months down the line.Just curious if anyone else can relate.Thank you all for being here .

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@packh1 You may be a medical anomaly. I have not taken these meds, but have experienced new, worrisome changes in my body when my health or medications changed, so I can relate.

I did some research and learned that the increase in blood glucose and A1-C while on these 3 meds is not usual. Jardiance is actually used to lower blood glucose in Type II diabetes, and metoprolol has a known propensity for slightly lowering it too. Only spironolactone is ever reported to SLIGHTLY increase fasting blood glucose levels. So I would say your cardiologist's dismissal of the drugs as a cause is normal, but you are still left to deal with it!

Perhaps whatever health incident pushed you into VTACH and put you on this path also affected your metabolism and pushed you from pre-diabetic to Type II? Maybe you need to talk to your GP about next steps?

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I read a lot of material about diabetes news, research, studies, etc. With recent significant increase in BG and no apparent reason, I’d likely see an Endocrinologist if possible. I realize it’s rather challenging to get a referral unless type 1…..from what my endo has said, but I’d try. They are in a better position to understand why this happens and to run tests that can reveal the true picture. In the meantime you could discuss nutrition with a dietitian, keeping your goals in mind. I hope you can get some answers.

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Do you ever do finger stick tests?
They can be a reality check. If you get normal readings when fasting or postprandial, that would be pretty good evidence of A1c anomaly.

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Profile picture for Sue, Volunteer Mentor @sueinmn

@packh1 You may be a medical anomaly. I have not taken these meds, but have experienced new, worrisome changes in my body when my health or medications changed, so I can relate.

I did some research and learned that the increase in blood glucose and A1-C while on these 3 meds is not usual. Jardiance is actually used to lower blood glucose in Type II diabetes, and metoprolol has a known propensity for slightly lowering it too. Only spironolactone is ever reported to SLIGHTLY increase fasting blood glucose levels. So I would say your cardiologist's dismissal of the drugs as a cause is normal, but you are still left to deal with it!

Perhaps whatever health incident pushed you into VTACH and put you on this path also affected your metabolism and pushed you from pre-diabetic to Type II? Maybe you need to talk to your GP about next steps?

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@sueinmn Sue, Thank you for your insights . Like you mentioned, I am wondering if the stress of the heart incident -ending up in ICU after wrong diagnosis , not getting clear answers, cardiac cath etc. put such a strain on my system that it triggered the jump from pre to diabetes .I just hope that when all gets settled i will get back to complete metabolic health.I appreciate your responding.

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Profile picture for celia16 @celia16

I read a lot of material about diabetes news, research, studies, etc. With recent significant increase in BG and no apparent reason, I’d likely see an Endocrinologist if possible. I realize it’s rather challenging to get a referral unless type 1…..from what my endo has said, but I’d try. They are in a better position to understand why this happens and to run tests that can reveal the true picture. In the meantime you could discuss nutrition with a dietitian, keeping your goals in mind. I hope you can get some answers.

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@celia16 Thanks, I am thinking an endocrinologist could be my next step.Fortunatley , with our health supplement we don't need referrals. Getting a timely appointment with a specialist is another matter.

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Profile picture for Scott R L @scottrl

Do you ever do finger stick tests?
They can be a reality check. If you get normal readings when fasting or postprandial, that would be pretty good evidence of A1c anomaly.

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@scottrl I have thought of getting my own testing materials. Wondering if due to prediabetes my insurance would cover it.May inquire. Thank you for your response-it is helpful.

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Profile picture for packh1 @packh1

@scottrl I have thought of getting my own testing materials. Wondering if due to prediabetes my insurance would cover it.May inquire. Thank you for your response-it is helpful.

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@packh1 Based on your A1-C, your GP can order the testing materials and monitor.

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Profile picture for packh1 @packh1

@celia16 Thanks, I am thinking an endocrinologist could be my next step.Fortunatley , with our health supplement we don't need referrals. Getting a timely appointment with a specialist is another matter.

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@packh1 , good. I hope they can get you in without delay. When looking at reasons for unexplained, significant increase in glucose levels, a specialist will likely tests your ability to make insulin. Have you had a C-peptide test? With type 2, the high BG levels are normally due to the body’s inability to utilize the insulin efficiently. Some people are thought to be type 2 but are actually early 1. I’m not saying that’s the case, but there are great benefits to confirming which it is so early, because early intervention makes a huge difference in treatment.

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Profile picture for packh1 @packh1

@scottrl I have thought of getting my own testing materials. Wondering if due to prediabetes my insurance would cover it.May inquire. Thank you for your response-it is helpful.

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@packh1 Even if you can't get a prescription right away, glucometer kits are pretty cheap. For $20-30, you can get a meter, ~100 test strips, lancing device, lancets, etc. (Look on Amazon or Walmart.com.)

Testing 2-3 times a day will give you at least a month of data. Your peace of mind might be worth the cost.

Good luck!

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I am a retired nurse who looks up everything that concerns my health and that of my husband. I do not take anything for absolute truth when it comes to someone saying "don't worry about it" when nobody knows your body better than you. So I did a brief AI search on Jardiance--which I highly suspect could be the problem since I have heard of adverse reactions to this "magic" weight loss drug. "Jardiance is designed to lower blood glucose levels, but in some cases, it may lead to a condition called euglycemic diabetic ketoacidosis, where blood glucose levels can be normal or even elevated despite the medication. It is important to monitor blood sugar levels regularly while on this medication." This is just one resource that I am sharing and I am not saying that this is what you are experiencing , but there are other resources online. Everyone is different; we are not all the same in our reaction to medications. You don't mention how old you are, but "pre-diabetic" is now the new BS diagnosis for everyone over 65 in my opinion. My husband got that diagnosis too and we take his blood gluscose level every week and it is never over 100, which is just the high level of "normal" according to the guidelines. He's 80 years old! If I were you, I would talk to your PCP or seek an opinion from your pharmacist regarding whether the medications you are on could be the culprit for the elevation. Cardiologists are not experts in every area of medication interactions. I remember my orthopedic surgeon telling me, when I asked for nerve pain relief at night from a fracture of the upper humerus, "I don't do pain management; I am a surgeon." This is the honest truth! I finally got him to begrudgingly give me a prescription for Amitriptyline, which is the gold standard treatment for nerve pain but "off label" use. Years ago, a neurologist told me about this when I had a severe dislocation of shoulder. My point is, there is something going on and you are correct to ask and be concerned. BTW: Good luck with the ablation; I had one in November of last year and the results have been great. Best wishes!

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