AI Overview Metoprolol use is associated with a mildly increased risk of new-onset type 2 diabetes, reduced insulin sensitivity, and elevated fasting blood glucose levels. These metabolic changes occur because the medication can decrease glucose uptake in muscles and influence how the body handles insulin.How Metoprolol Affects Blood SugarLower insulin sensitivity: Body cells may not respond as well to insulin, making it harder to move sugar from the blood into the cells.Higher fasting glucose: Long-term use can lead to small increases in resting blood sugar and insulin levels.Masked low blood sugar signs: Beta-blockers can hide warning signs like a fast heartbeat during low blood sugar, though sweating usually remains unaffected.Managing the RiskMonitor levels: Regular blood glucose or HbA1c checks help catch upward trends early if you take metoprolol.Weigh benefits and risks: For heart conditions like heart failure or high blood pressure, the heart-protective benefits of beta-blockers often outweigh the metabolic risks.Talk to a doctor: Never stop taking a heart medication without medical advice; alternative treatments or lifestyle adjustments can help manage blood sugar.