Pain in leg muscles, tendons, and knees after Bilateral PE on Eliquis

Posted by smasneri @smasneri, Jul 6, 2023

One month after massive bilateral PE and taking 5 mg twice daily. Experiencing constant and continual pain in legs, mainly behind both knees, in tendons, and some muscle flare ups. Have had two ultrasounds and a CT scan on both legs since I was diagnosed June 6 and they are negative. My D Diemer is .43 and all vitals strong and regular. Echocardiogram shows no strain on heart. We have ruled most everything else out. No trauma to legs, no cuts, bruises or strains. Is this related to the Eliquis? My local hematologist wants me on it for another 5 months, I won’t be able to make that unless this subsides. Anyone else out there having this issue? Recommendations?

Interested in more discussions like this? Go to the Heart & Blood Health Support Group.

Profile picture for charley7wills @charley7wills

@michaelalexander Good luck with that! They would only switch me from Xarelto to Eliquis and I had to threaten to quit taking the Xarelto. They both caused pain in muscles and joints, just hit different body parts to differing degrees. 🙏

Jump to this post

@charley7wills Exactly my experience! Then, even though my clot was stable and the cause of circulation problems that caused clot were resolved, I couldn’t get any medical professional to say I could quit Eliquis. So, I did anyway. That was 6 weeks ago and now I’m having to have treatment for the side effects! Both should be researched more thoroughly.

REPLY
Profile picture for charley7wills @charley7wills

@charley7wills Exactly my experience! Then, even though my clot was stable and the cause of circulation problems that caused clot were resolved, I couldn’t get any medical professional to say I could quit Eliquis. So, I did anyway. That was 6 weeks ago and now I’m having to have treatment for the side effects! Both should be researched more thoroughly.

Jump to this post

@charley7wills Oh, silly me🤣. I just replied to my own reply.

REPLY

Yes it was so debilitating thst i trued to swtch med or dosage but dkc said no.I thought i was goung to die.I taje galf a bitten half2.5 aporox twice day niw.They wont issue 2.5 mg pills.Cramping less after 2 days but still suoer un4comfortable!

REPLY
Profile picture for michaelalexander @michaelalexander

I'm experiencing everything that you described. Have been to emergency 3 times in the last 2 months. Doctors saying it's just my arthritis but the symptoms are gradually worsening with every day. I have to use crutches now to get around. I see my Vascular surgeon on Monday and will insist on another blood thinner. At the rate I'm going, I will soon be in a wheel chair. I can hardly lift up my legs to put my pants on because of the excruciating knee pain. I almost want to stop the Eliquis on my own as I see my own rapid determination. I'm willing to take my chances.

Jump to this post

@michaelalexander
Hi, i’ve been going back and re-reading messages about Eliquis wondering how you made out are you still on it or were you switched to another blood thinner?
After my heart attack, I was taking Eliquis for 15 months and month after starting it I noticed my legs were stiff in. It was hard to walk since then they’ve been getting worse. I had x-rays done and was told I have arthritis in my knees, but my issues in my legs are more than just arthritis in the knees. I find it very hard to walk around and I feel the same way. It just keeps up. I will be in a wheelchair but a few months ago I told my cardiologist I wanted to get off Eliquis. I mentioned to her about the side effects with my weakness and stiffness in my legs, but she denied Eliquis had any side effects like that so she put me on Warafin.. well, that was just as bad. I was on it for three weeks and of course I had to go twice a week to get blood work done so they could regulate the dosage but after three weeks on it I also had stomach issues most every day I would feel nausea and I had hair loss. I told my doctor I wanted to go back on Eliquis. I really didn’t know of any other option so I’ve been back on it now for almost a month and it seems like my legs are worse. I
Know people that had heart attack or bypasses and the only thing they take for their heart is a baby aspirin. I really don’t understand why I have to stay on this blood thinner. I thought it would only be for a year.

REPLY

I’m another one who’s on Eliquis and is having the same issues with my legs,finding it very hard to walk around Or even to stand up for very long. I was switched over to Warafin But only stared on it for three weeks because I had side effects with that, Didn’t know of any other options so I went back on Eliquis and I feel like my legs have gotten worse.. Don’t understand why doctors don’t know about the side effects Eliquis causes

REPLY

Yes.I am hopeing to try another med. My muscles become hard like rock but i am not dead an my lungs are breating after PE.

REPLY

Wow. All of the above confirms what I've been experiencing after starting Eliquis. Been on Atorvastatin for five years, and symptoms had moderated, but became MUCH worse after starting Eliquis. My knees are weak, I tore a MCL in my right knee just standing up, my arthritis symptoms are significantly worse, the neuropathy in my foot is worse, my feet hurt - and my cardiologist has been basically dismissive. Yeah, I have multiple heart conditions including AFib, microvascular disease, tachacardia - but I cannot tolerate these symptoms that are threatening my ability even to earn a living playing music, and guitar. I'm 69, and pretty disgusted with the lack of knowledge, expertise and even fundamental concern from the 'specialists.' Going back to baby aspirins and stopping the Eliquis, no matter what the 'experts' say. The reports of bad side effects from Eliquis are overwhelming.

REPLY
Profile picture for ruth36 @ruth36

I’m another one who’s on Eliquis and is having the same issues with my legs,finding it very hard to walk around Or even to stand up for very long. I was switched over to Warafin But only stared on it for three weeks because I had side effects with that, Didn’t know of any other options so I went back on Eliquis and I feel like my legs have gotten worse.. Don’t understand why doctors don’t know about the side effects Eliquis causes

Jump to this post

@ruth36 Ditto. The 'specialists' seem to be ignorant of the vast number of consistent reports about Eliquis side effects. It is pretty maddening.

REPLY
Please sign in or register to post a reply.