Wow. All of the above confirms what I've been experiencing after starting Eliquis. Been on Atorvastatin for five years, and symptoms had moderated, but became MUCH worse after starting Eliquis. My knees are weak, I tore a MCL in my right knee just standing up, my arthritis symptoms are significantly worse, the neuropathy in my foot is worse, my feet hurt - and my cardiologist has been basically dismissive. Yeah, I have multiple heart conditions including AFib, microvascular disease, tachacardia - but I cannot tolerate these symptoms that are threatening my ability even to earn a living playing music, and guitar. I'm 69, and pretty disgusted with the lack of knowledge, expertise and even fundamental concern from the 'specialists.' Going back to baby aspirins and stopping the Eliquis, no matter what the 'experts' say. The reports of bad side effects from Eliquis are overwhelming.