Any experience with Nexletol or Nexlezet?

Yes. For decades my doctors would put me on different statins, different doses and I had horrible side effects, I thought I would have to quit working and go on disability from taking those drugs. I was not willing to have a horrible life just to lower cholesterol. I would rather live less years happy than more miserable. My life was ruined. I tried Repatha. Same thing. I am now on Nexletol for 6 weeks without side effects so far. I was VERY skeptical because of the many years with bad side effects. I am still skeptical but taking it one day at a time. I can gauge my strength at yoga. How easily can I do poses and how long can I hold them? Right now the answer is that yoga is going great.

@llynch17056 Thanks for your post! I have had the same experience. In fact, I have not quite believed my positive experience with Nexletol. If I have any setback in my physical activity I have tried to blame it on Nexletol, but every time it has not been the case.

@poppy55 I admit that the “tendon rupture” potential side effect makes me a bit concerned. I have already had my uric acid tested and it is fine so far. I will be keeping a close watch on that.

@llynch17056 Yeah, the tendon rupture concern is huge. So far so good. I’ve been taking daily it for 5 months now without an issue. At 71 years old I have a torn meniscus, a cyst in my spine, scoliosis and sciatica, but continue to exercise regularly. As long as I can cycle and do resistance training I’m happy. Thanks again for your post. Made my day.

I too am unable to take statins and was excited to find an alternative drug. But after several months of taking Nexletol, I have the same side effects as I did with statins— severe muscle cramping literally all over my body from jaw to toes! Weakness in limbs, and I believe even my voice was affected. I quit cold turkey because I could no longer endure the cramps— particularly bad in my thighs and diaphragm. My hands cramped so badly that I had to pry my thumb back in place. I stupidly kept looking for other explanations and had 3 MRI’s, CT scans, bloodwork done, saw two internal med Drs— all with nothing showing up. I had convinced myself that I had no side effects from Nexletol and then upon looking it up— there it was! I had every side effect except ligament involvement. I cannot believe how much better I feel having discontinued this drug! Voice back to normal, most of cramping resolved, stronger in my limbs. Not sure where to turn for cholesterol treatment. Dr did mention a twice a year injection. But now afraid to try anything! So user beware!

@cvs46 you might want to try a supplement called Durable Heart. You can get it online. Intolerant to statins and Repatha, I tried it with my cardiologists blessing - it comes with a money back guarantee if your labs don’t improve! Mine improved a lot, happy to say.

@con123 thank you! I will!