I too am unable to take statins and was excited to find an alternative drug. But after several months of taking Nexletol, I have the same side effects as I did with statins— severe muscle cramping literally all over my body from jaw to toes! Weakness in limbs, and I believe even my voice was affected. I quit cold turkey because I could no longer endure the cramps— particularly bad in my thighs and diaphragm. My hands cramped so badly that I had to pry my thumb back in place. I stupidly kept looking for other explanations and had 3 MRI’s, CT scans, bloodwork done, saw two internal med Drs— all with nothing showing up. I had convinced myself that I had no side effects from Nexletol and then upon looking it up— there it was! I had every side effect except ligament involvement. I cannot believe how much better I feel having discontinued this drug! Voice back to normal, most of cramping resolved, stronger in my limbs. Not sure where to turn for cholesterol treatment. Dr did mention a twice a year injection. But now afraid to try anything! So user beware!