Is anyone on Repatha for cholesterol...

Posted by porscha @porscha, Dec 7, 2025

I'm taking Repatha shots every 2 weeks for cholesterol. So far, so good.
Has anyone experienced side effects...

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Profile picture for czechgirl @czechgirl

Yes- started w/repatha but was allergic. Then went to Praluent about 3yrs ago. Have had no issues but bruising @ injection site. Very happy with results.

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@czechgirl what happened to you when you took it. I am supposed to take it and am afraid to take it while I am alone. The Dr. should be the with you for the first dose. Happy to hear you are much better.

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Profile picture for gcgc @gcgc

@czechgirl what happened to you when you took it. I am supposed to take it and am afraid to take it while I am alone. The Dr. should be the with you for the first dose. Happy to hear you are much better.

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@gcgc I didn’t have any side effects & I found the injection pen very easy to use. I inject three inches to the side of my belly button and alternate sides w/ each use. I’ll admit taking it for the first few times I did stay at home a few hours afterwards, but haven’t had any issues- ever. It’s wise to be initially cautious until u r sure you can take this med safely. Hope this helps🙂

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Thanks for the information. Will do.

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Profile picture for gcgc @gcgc

@czechgirl what happened to you when you took it. I am supposed to take it and am afraid to take it while I am alone. The Dr. should be the with you for the first dose. Happy to hear you are much better.

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@czechgirl, I think @gcgc was referencing your comment you made that you started with Repatha but was allergic.

How long did you take Repatha? What side effects did you experience?

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Ok - sorry - yes, allergy to repatha showed up when taking first dose as a large 3 inch diameter hot welt at the injection site on my thigh. I was immediately taken off repatha and put on Praluent. The welt took several days to reduce in size/resolve. After talking thru w/ care team, I now only inject in my abdomen 😉

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Profile picture for Janell, Volunteer Mentor @jlharsh

@mooseman

I went to the home page and searched for “Praluent”. There are several discussion you can browse to find others discussing the drug:

- Connect Discussions related to Praluent
https://connect.mayoclinic.org/search/
Are you taking Praluent?

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@jlharsh

Thanks !

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Profile picture for Janell, Volunteer Mentor @jlharsh

@mooseman

I went to the home page and searched for “Praluent”. There are several discussion you can browse to find others discussing the drug:

- Connect Discussions related to Praluent
https://connect.mayoclinic.org/search/
Are you taking Praluent?

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@jlharsh

Thanks ! No, not taking yet. Waiting on approval from my Part D.

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