How long did you take a statin before feeling side effects?

Posted by swilkins1974 @swilkins1974, May 24, 2023

How long did you take a statin before you started feeling side-effects?

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@mayoconnectuser1

So, your HDL increased by 50% due to diet? This seems out of the norm for HDL movement ... for any reason.

I've seen reports where HDL increases a bit by increasing exercise, and better diet, but, 50% is a HUGE movement for HDL?

40 is considered "Good" in some medical articles, with 60 being consider "High."

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It most certainly was possible for me. My HDL has been between 75-82 mg/dl for the past four years. For the ~ 15 years before that, it ran 42-51 mg/dl.

What changed? I lost 55 lbs on a low-carb diet combined with daily exercise. And I have kept it all off without any backsliding. And my rosuvastatin dose has been halved.

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@whineboy

It most certainly was possible for me. My HDL has been between 75-82 mg/dl for the past four years. For the ~ 15 years before that, it ran 42-51 mg/dl.

What changed? I lost 55 lbs on a low-carb diet combined with daily exercise. And I have kept it all off without any backsliding. And my rosuvastatin dose has been halved.

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Wow - great job changing your lifestyle!

Here are a few articles with mention of extremely high HDL ... I can't interpret this, but your HDL seems incredibly high based on my limited knowledge. At least one of the articles refers to a Danish study that indicated lowest mortality in men of an average of 73 - so, you're right there. Other articles infer you are pretty high and should review other factors. Again, I'm not qualified to comment further.

https://my.clevelandclinic.org/health/articles/24395-hdl-cholesterol#:~:text=An%20elevated%2C%20or%20abnormally%20high,trouble%20getting%20rid%20of%20it.https://www.webmd.com/cholesterol-management/good-cholesterol-too-highhttps://www.uspharmacist.com/article/common-otc-drugs-supplements-potentially-can-confound-laboratory-results-1-1https://www.heartuk.org.uk/genetic-conditions/high-hdl-cholesterolhttps://pubmed.ncbi.nlm.nih.gov/35039162/https://academic.oup.com/eurheartj/article/38/32/2478/3608700
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Thanks for your concern. I have my annual cardiologist visit in a month and can ask if HDL can be too high.
I saw the hazard ratio on one of the srudies was 1.44 - that’s barely significant, my understanding is that the HR has to be 2.5 or better to be meaningful.
Edit: I also understand it’s a function of my low-carb eating.
Edit 2: You inspired me to look over my most recent lab results. They show my HDL is in the green and there is no high-end limiting value. Still, worth checking up on, I agree.

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