Started Repatha - Side Effects

I had a NSTEMI in October last year. I was put on 2 different statins that I could not tolerate. So the cardiologist prescribed Rapatha. I had horrible GI issues, including constant nausea and frequent diarrhea. I lost about 8 lbs in 2 months just from not eating. I’m now on pravastatin for about 2 weeks and so far no adverse side effects. Just my experience. Of course the doc said they had never heard of that (really?!).

We are all made so differently. I am lucky not to have side effects and the impact Repatha has had on my lipid profile is immense. I needed to hear your story to remember gratitude.

I am also struggling with the same issues on this medication. I have decided it was less stress to go back on Crestor but now it takes 2 months for this to get out of my system. It's just been 10 days I got 50 more to go. I only took this medicine 2 times and it did this to me. I really feel for you.

This could be written by me. My internist agrees that my cholesterol ratio is good even though my bad cholesterol number is high and that LPa is a more concerning number. I found a supplement that I tolerate well that has lowered my LPa by 60 points

Here’s a follow-up: I’ve was having chest pains, so I had a nuclear stress test on Monday. This morning the office called and said it was abnormal. Got scheduled back into the cathlab at noon. Turns out everything looked good, my stent was clear. The abnormal stress test was a false positive which the doc said happens more often with women. The blood tests showed that my electrolytes were out of whack. That’s from the extreme GI issues. It can be very serious, so make sure your doc understands how lousy you feel. I’m home now, and grateful that my arteries all looked good. Thanks for responses.

Glad your arteries are doing well. You must be so relieved.

I had adverse side effects that took a while to figure out were connected. How many injections did you take, and were your symptoms progressive the more injections you took?

What was the supplement that lowered your Lp(a) by 40%? I have been taking Nattokinase for years and haven't noticed that much of an effect. Thanks!

We used the syringes, so after the first 3 doses we started doing half doses to see if I could tolerate that. The side effects were always bad , so I didn’t notice if they got worse.

Beta-Sitosterol Plant Sterois

I was started on Rapatha two months ago. I am not feeling well since. I have flu like symptoms including fatigue, aches abdominal distress with a bloated feeling and feeling full (no appetite).
I was on Praluent for several years with no side effects but our insurance company stopped covering the cost.
I am usually an energetic person so it’s hard for me to become accustomed to my lack of energy. I am contacting my Cardiologist to discuss this as I feel this is having a negative impact on my quality of life. I would appreciate any input.