Any experience with the P Tau 217 plasma test for Alzheimer's?

Would love to hear about this.

Yes. My husband’s Tau 217 was .83. Very accurate measure for Alzheimer’s. I’m sorry to join you on this. 🙏🏻

You may have the numbers mixed up. .085 is low. Very high would be .85. The typical is .18 or below. Remove the decimal points and it might be easier to understand.
8 1/2 low, 18 typical 85 very high.

More important is how is he in everyday life? Is he forgetting things? Can he be trusted? Then, are there any treatments suitable for him?

My husband did that test and tested low, .07, so at least we ruled out Alzheimers.

Husband’s was .923 on the Lumipulse blood test. Subsequent PET scan showed significant amalyoid. We first suspected something amiss a year ago. He is in the MCI phase and functioning pretty well. He has just started Kisunla infusions; it took awhile to get set up with neurologist, get clinical testing all done, and get approval. We are hoping for the best.

My husband has a ptau level of 1.67. I wish I could say that was a typo. Our lab normal range stated .22 or below. PET showed frequent and widespread amyloid plaques. He is still in MCI stage as we were just diagnosed in February. He is only 61. He started Aricept in Feb and will double dose in May if all is going well. We were not comfortable with the infusions, as he was positive for every aspect that cause the most negative side effects. This is happening all too fast. He is still working and doesn't want to retire, but I see that coming fast with the decline.

I feel for everyone on here and am thankful for the support everyone shows for one another. Love and hugs to everyone dealing with this horrific disease.

@mugsarella, saw your post about your husband. Hope things are going well. My wife was recently diagnosed with AD, MCI, after the ptau test, PET scan and neurological testing all were positive for AD. She is going through the process to start Kinsula infusions. Just wondering how what you and your husbands' experience is so far with the infusions. Any info would be appreciated.

@gilkesl Did your primary care do the test? Is this fairly new?

My husband had the blood test to detect Tau particles and amyloid plaques. His results do not indicate Alzheimer's disease. He does however have late stage moderate dementia. Given his history, it is most likely vascular dementia. We did the test to determine if the infusions might have been an option. They are not.

@paul55
It did take a bit of time to get insurance approval. (Have not seen a bill yet, but it appears insurance will cover this.) There was also time involved in scheduling for another MRI, which was a baseline MRI very near infusion time, as well as another visit with the neurologist, so all told, it was almost 3 months’ time from initiating the request for Kisunla to actually getting to the treatment. My husband’s first Kisunla infusion was a reduced dose, and it went without incident. The nurse practioner answered our questions thoroughly beforehand. I was vigilant, watching my husband for any aftereffects, and the day went on as normal. Immediately afterwards, he did say his head felt a little different, but he was not dizzy or headachy, and the infusion center nurse evaluated it as not serious. He worked outside for awhile that afternoon, and we attended a show for which we previously had gotten tickets that evening. He became so sleepy-tired at the show that we left at intermission. I thought that his brain had really worked hard with the Kisunla because he was definitely more tired than normal. He slept very well that night and get up refreshed in the morning. It’s been three days since the infusion, and there have been no untoward reactions.
I might add that it was just over a year from the time that I first became concerned about his memory problems to the date of this first infusion. It is a relief to have the first infusion behind us, and we are hopeful that our timing was right and that the progression of MCI due to AD will be slower. It is already such an adjustment to live with MCI, and we are hoping research brings new findings if his progress is slowed down.

Hope this helps!