What's your experience with Ozempic or Saxenda for weight loss?

Looking for reassurance and advice — elevated liver enzymes and small lung nodules

Hi everyone,

I’m looking for a bit of guidance and reassurance. I’ve been really anxious about my recent health issues and thought maybe someone here has been through something similar.

I was on Ozempic for about three years and lost around 80 lbs. I was T2D, but it has “cured” itself. I stopped taking ozempic in May because it was making me feel sick. My bloodwork in late June and early July showed my liver enzymes were around 700. My spleen was enlarged as well as the liver and a few lymph nodes too. My MRI later showed no lesions or masses, and my kidneys are excellent. My enzymes are still elevated but fluctuating, and my doctor believes it’s due to inflammation and stress from the medication. I also don’t have a gallbladder.

On top of that, I have several small lung nodules. The specialists said they likely look like inflammation or scarring rather than cancer. One has shrank. My bloodwork and tumor markers are normal, and I have no symptoms. They’re requesting a PET scan and possibly a biopsy to rule cancer out, but my doctors have said this is just to be thorough. He believes inflammation to be high on the list.

I’m wondering if anyone here has experienced something similar — elevated liver enzymes after stopping Ozempic, or benign lung nodules due to inflammation.
I’d love to hear what helped you heal and what lifestyle or nutritional changes made a difference.

Thank you so much for reading. I’ve been trying to stay calm, but this has been really scary. Any encouragement or insight would mean a lot. I have medical anxiety that is currently out of control.

Warmly,
Tracy

I take Mounjaro weekly. It is called Zepbound for weight loss. It works fantastic!! I have T2 diabetes and have gone from 289 lbs to 142 lbs! Good luck!!

I am on the weekly Mounjaro shot and it constipates me so bad! Doctor recommended Miralax every morning for the first 10 days, then every other day after that. I have never been so regular and no longer struggling! Highly recommend Miralax! One capful in 1/4 cup of Gaterade Zero and zero taste!!

@cntrlcoastgirl
I am curious if the Miralax continues to work after a longer time? I have Type 2 and took Ozempic 2MG for over a year; my pcp switched me to mounjaro 5mg and now I have very significant constipation. The pcp then had me take senna - only a small improvement. I would be interested your progress with Miralax and hearing from anyone else that has had similar side effects with fairly low level mounjaro….

@bournejr
I’ve been using MiraLAX occasionally for about five or six years. I take a lot of drug drugs and some of them cause constipation. I take 2 Colace twice a day and one Senna twice a day and they usually keep me fairly regular but every few days I need to use MiraLAX after I have not gone for two days. It works pretty quickly almost all the time within two or three hours I’m ready to go.

You don’t need to buy the brand name MiraLAX there are much cheaper options available with the exact same ingredients.

@jeffmarc
Hi Jeff:
This is very helpful. However, I worry a bit about my doctor really doesn’t like my taking much of the senna - I do have some Colace, I might try, My doctor is really against Colace,….. I’m wondering if I got up to 7.5 MG (which he pcp wants me to do) if it will get any better (i suspect not).