What's your experience with Ozempic or Saxenda for weight loss?

I take Mounjaro weekly. It is called Zepbound for weight loss. It works fantastic!! I have T2 diabetes and have gone from 289 lbs to 142 lbs! Good luck!!

@cntrlcoastgirl
I started Mounjaro for diabetes late June. I'd been on Jardiance for 4 years, but with severe yeast infections side effects. I am up to 7.5 once weekly. Side effects of loose stools and indigestion are subsiding. I'm at week 14 and have only lost 18 pounds. Doctor informed that she won't be raising dosage as my A1C is 5.3 and protein levels are low. She advocates for losing weight slowly, 1 ¼ pound weekly. I am frustrated bc I have modified my diet drastically and walking 3 x a week. (Recovering from hip replacement.) I'm curious as to what dosage you are on and how long did it take for you to lose that much weight? I would be happy with losing 50# but definitely would welcome more.

@beachy - awesome you are walking 3 times per week now and you've modified your diet drastically. The latter is especially hard to do.

How are your side effects from the shot this week?

@lisalucier Thanks for asking bc I was actually going to ask about other's side effects. Yesterday I experienced severe stomach cramps and vomited all day. Had regular bowell movement. Called Dr office who suggested taking pepto bismol and sipping room temp water with electrolytes. If didn't subside, go to emergency room and stop mounjaro. I've read that pancreatic can occur. It's hard for me to determine if this was food poisoning bc regrettably, I ate a fast food burger on Tuesday, or side effects from Mounjaro. Managed to get plenty of sleep. While vomiting has stopped, I'm still experiencing stomach cramps, but not as severe. Calling back Dr office soon. Anyone with experience same stomach problems? Thank you.

@beachy - I've had both of those side effects when I was on semaglutide (Wegovy). Rather awful.

Taking medicine to counteract the effects of another medicine is kinda crazy, admittedly. However, as I was determined to go on with my weight loss shots, my doctor, though also a little hesitant for the same reason, prescribed: hycosamine for the cramping and prochlorperazine for the nausea. These helped a lot.

I also used ginger ale and ginger lozenges sometimes for nausea. My husband also had me put "barf bags" in all our vehicles, cause sometimes nausea would come on and progress to vomiting in a flash.

Have you gotten to talk to your doctor's office further this morning about your side effects?

@lisalucier ty for response, very helpful. Nurse said continue electrolytes, eat salty crackers try banana or rice later. Room temp peppermint tea. I do have ginger chews that I'll try. Monitoring, if pain worsens, they will see me tomorrow. I don't want to stop Mounjaro yet, but these side effects are awful. Maybe I could ask for a step-down back to 5Mg instead of 7.5. As of now, they are recommending I skip dose this Sunday.

@beachy - The best next steps are all super hard to figure out when you are experiencing what seem like extreme side effects. I am not medical staff in any sense, but this is what happened in my experience: I eventually got so weary of the extreme cramping, random vomiting and bad diarrhea that even caused a little "explosion" in my bed twice overnight, that I finally asked my doctor to switch me from semaglutide (Wegovy) to tirzepatide (Zepbound). She agreed that my side effects were bad and put me on the path to a switch.

In the end, I feel like this was a mistake for me, simply due to time constraints with my insurance coverage. I had to be off all weight loss meds for one month, to be sure the side effects were coming from the semaglutide (Wegovy). They were, and all side effects stopped. Then I had to wait a little for my insurance to authorize the tirzepatide (Zepbound). During this time off of the shots, my weight went up quite a bit. Then I had to start all over with the tirzepatide (Zepbound). By the time I got to the top dose, my insurance coverage for weight loss shots had run out. And for whatever reason, the tirzepatide (Zepbound) did not work for me at all - I lost maybe 1 pound total on it. I'd lost 53 pounds in my time on semaglutide (Wegovy). I essentially went backwards in my weight loss, which was frustrating.

So, in retrospect, I wish I had stayed on the semaglutide (Wegovy) and figured out with my doctor how to work with it and the side effects (e.g., going down in dosage, frequency of shots, antidiarrheal meds).

Ultimately, only you can say what is the best path for you, beachy.

Hoping perhaps other members in this discussion on weight loss shots such as @edwardw @therese0327 @writer418 @projfan @ekrahenbuhl will have some input for you on the nausea/vomiting/cramping side effects you've had to deal with as you try to determine how to manage this and the way forward.

@beachy - The best next steps are all super hard to figure out when you are experiencing what seem like extreme side effects. I am not medical staff in any sense, but this is what happened in my experience: I eventually got so weary of the extreme cramping, random vomiting and bad diarrhea that even caused a little "explosion" in my bed twice overnight, that I finally asked my doctor to switch me from semaglutide (Wegovy) to tirzepatide (Zepbound). She agreed that my side effects were bad and put me on the path to a switch.

In the end, I feel like this was a mistake for me, simply due to time constraints with my insurance coverage. I had to be off all weight loss meds for one month, to be sure the side effects were coming from the semaglutide (Wegovy). They were, and all side effects stopped. Then I had to wait a little for my insurance to authorize the tirzepatide (Zepbound). During this time off of the shots, my weight went up quite a bit. Then I had to start all over with the tirzepatide (Zepbound). By the time I got to the top dose, my insurance coverage for weight loss shots had run out. And for whatever reason, the tirzepatide (Zepbound) did not work for me at all - I lost maybe 1 pound total on it. I'd lost 53 pounds in my time on semaglutide (Wegovy). I essentially went backwards in my weight loss, which was frustrating.

So, in retrospect, I wish I had stayed on the semaglutide (Wegovy) and figured out with my doctor how to work with it and the side effects (e.g., going down in dosage, frequency of shots, antidiarrheal meds).

Ultimately, only you can say what is the best path for you, beachy.

Hoping perhaps other members in this discussion on weight loss shots such as @edwardw @therese0327 @writer418 @projfan @ekrahenbuhl will have some input for you on the nausea/vomiting/cramping side effects you've had to deal with as you try to determine how to manage this and the way forward.

@beachy - The best next steps are all super hard to figure out when you are experiencing what seem like extreme side effects. I am not medical staff in any sense, but this is what happened in my experience: I eventually got so weary of the extreme cramping, random vomiting and bad diarrhea that even caused a little "explosion" in my bed twice overnight, that I finally asked my doctor to switch me from semaglutide (Wegovy) to tirzepatide (Zepbound). She agreed that my side effects were bad and put me on the path to a switch.

In the end, I feel like this was a mistake for me, simply due to time constraints with my insurance coverage. I had to be off all weight loss meds for one month, to be sure the side effects were coming from the semaglutide (Wegovy). They were, and all side effects stopped. Then I had to wait a little for my insurance to authorize the tirzepatide (Zepbound). During this time off of the shots, my weight went up quite a bit. Then I had to start all over with the tirzepatide (Zepbound). By the time I got to the top dose, my insurance coverage for weight loss shots had run out. And for whatever reason, the tirzepatide (Zepbound) did not work for me at all - I lost maybe 1 pound total on it. I'd lost 53 pounds in my time on semaglutide (Wegovy). I essentially went backwards in my weight loss, which was frustrating.

So, in retrospect, I wish I had stayed on the semaglutide (Wegovy) and figured out with my doctor how to work with it and the side effects (e.g., going down in dosage, frequency of shots, antidiarrheal meds).

Ultimately, only you can say what is the best path for you, beachy.

Hoping perhaps other members in this discussion on weight loss shots such as @edwardw @therese0327 @writer418 @projfan @ekrahenbuhl will have some input for you on the nausea/vomiting/cramping side effects you've had to deal with as you try to determine how to manage this and the way forward.