@mgrimes5
Good morning,
Has your spleen been removed?
Jake

Hi @mgrimes5, I's like to welcome you to Mayo Clinic Connect. You came to the right place to seek possible causes of high platelet count with a negative JAK2 test.
I know that @shenriq and @mjpm2406 had positive JAK2s but perhaps they can lend some insight on what their physicians tested for prior to finding the mutation.
@mgrimes5 has your physician checked for an infection, anemia or low iron?

Hi @mgrimes5, wondering how you are doing and if your physician has followed up at all yet?

Myself, platelets getting higher, was told I have JAK 2 mutation – clueless as to what determined the JAK 2 diagnosis – I have the blood work print out.
Values look fine. For the Platelets he said to take an aspirin daily and see him in 6 months. Doctor is an Oncologist Hematologist. .