I am afraid of trying Tymlos and other drugs due to side effects

Am following this important subject about OA and safest drug. Keep reading that a majority of people are also, very afraid of these drugs. A summary I read was written that 'while they help for a time' going forward there are none that keep helping. This is such a great website and keep reading with the hope that I will learn something else other than to be so terrified - as the OA I have has made my hands almost impossible to use or move as are all swollen and painful. Wait till noon for 2nd dose of Tylenol to lessen the symptoms. 5 pm even better but not like I am pain free. Even walking with a cane, hurts - handle so hard as well on the can. At the same time, need a hip replacement surgery. Can't have that when my upper body is under siege. Wishing all in the same boat, luck with this, have to keep hoping and finding answers.

I'd like to see the research that indicates most people are afraid of Osteoporosis meds. Please post. Thanks

Sent from my GalaxyOh no.....those fractures are painful.I did have Kyphoplasty surgery twice at 66yrs old. If you aren't familiar with it....quick outpatient surgery. Similar to a scissor jack that you would change a tire with.Non invasive, no scar.It is done under anesthesia and requires an MRI. My bones were soft. The surgeon said he could actually move them around. That's how quickly I crashed after stopping Prolia.I, and my doctor are pleasantly surprised at the success I have had with Tymlos.He says that is now his go to prescription for severe osteoporosis.I will say that the first injection was excrutiating but it only lasted a few minutes. Good hubby coaching me to take deep breaths and rubbing my back. I was petrified to take the next injection, but it never happened again. I think it was just a mega dose shock to my system?? The doctor said it happens, but not to everyone. Oddly, it seems like whenever my knees hurt or I recently broke a toe, the Tymlos seems to go right to the damaged bones....it's weird but suddenly my knee tingled and same with my toe....But you need to decide what's best for you. I get frustrated with doctors who tend to brush of my concerns or over-medicate....grrrrr. ASK QUESTIONS!! No matter how much of the doctors time you take, he should answer all your questions and address all your concerns. Make a list.Keep me posted how you are doing and what you decided to do.Take good care of yourself.

Sorry for late reply. I have Mayo stuff go to this one email I don't access enough. And it's for my "important" stuff so usually I'm just looking for that when I come here, like a bank thing or whatever.

Funny a friend JUST told me his wife was on Actonel and I was surprised, she works out, lifts weights, I didn't think she had the problem. I didn't know Actonel but Googled and see it is like Fosamax Which is what my general doc said in last visit I should start with, that it's 'tried and true.' Plus my dentist said better with shorter half life, you can just stop it if you need work done.

My sister in law did start with Reclast because she said she didn't want to deal with the possible stomach issues of Fosamax. Those don't sound so great to me either.

But yet it was weird to suggest some one whose worst score was 1.9 go on Evenity.

This is what I want https://melioguide.com/osteoporosis-exercises/liftmor-osteoporosis-osteopenia/

That's the way I ALWAYS feel. Why I have done nothing so far like an ostrich (except work out but not with high enough weights apparently and also take supplements, sometimes Algae Cal, sometimes not. I want this thing.
https://pmc.ncbi.nlm.nih.gov/articles/PMC12035697/

Are you post menopausal?

yes, and started using HRT at 50

I was already on Boniva, which is like fosomax for 5 years. I didn’t take anything for years. Now I’m back on Prolia. Osteoporosis is also considered a genetic disorder. My mom who swam, danced and worked out had osteoporosis as well. I’m in great shape, eat healthy and work out practically everyday doing something. My numbers aren’t that bad. They are all just below normal. I tried these machines and they didn’t do much for me. I never had to go on Tymlos. I was off the Prolia for 4 months and worked out like crazy and when I was able to go back on I did the same. I was always concerned about the rebound. I guess I got lucky or my core and hips were not as bad. I’m very thankful.

I am on Tymlos . Started at 1/4 dose and slowly worked my way up to full dose over several weeks. No side effects.

Some people never reach the full dose because they can't tolerate it, so they max out at 5-6 clicks. It's still a therapeutic dose, if not as strong as the full dose.