stopping Carvedilol (Coreg): When will the effects wear off?

Posted by teatime @teatime, Apr 28, 2016

Hi everyone,

I am glad to be a part of this community. Please foregive the long post. I was wondering if anyone has had a hard time while being on and going off Carvedilol (Coreg).

I am an active 45 year old mom of a young child. I have always tried to eat healthily and keep in shape (I do yoga, pilates and, run about 5k 2x per week). My BP has always been pretty good, but since my 40´s it has gone up a bit (heredity factors play a role). My BP and heart rate also “spike” when I get stressed or anxious, but for the most part are pretty level during normal times. I do have anxious moments, but I would not say anxiety has been a major life problem. At my last check (Feb 2016), and after wearing a 24 hour BP monitor, my cardiologist suggested I start Carvedilol 6.25 1x per day (quite a low dose) for the spikes and to keep the heart from getting too excited. I agreed that maybe it was a good idea and started over two months ago. Other than stimulating rapid bowel movements, I did not notice any side effects at first. I would say about three to four weeks into taking the Carvedilol, I began not sleeping well. I also noticed my heart pounding, like a bass drum, slowly and steadily, at times. Then the heart pounding began to wake me up at night (it turns out my HR was down in the high 40s at night). Some nights I even felt my chest muscles vibrate, as if a phone on silence mode was on top of my chest. I started to notice this more and more and then I would have a few normal nights, so I figured I would just talk about this at my next cardio check (booked out in June). I also noticed I was getting more and more anxious. I wasn’t too sure why little things were beginning to bother me. I thought it was hormones, PMS, whatever, and started looking for someone like a therapist to talk to.

The previous week was bad. I woke up from a few nightmares and I started to panic in bed, just woken up from sleep. I had three nights of waking up to panic attacks and body shakes. The experiences made me very nervous. At this point I started looking into the side effects of Carvedilol and I was seeing not only chest pounding, but in rare cases reported effects of nightmares, visual disturbances, tremors, anxiety. I also know one does not simply stop a beta blocker, so we talked about tapering down. I tapered down for four days, and then I got in to see another cardiologist on Monday and he said just stop immediately. The effects are rare, but they have been noted. Going off this medication has been frightening. I feel weak and shaky all the time, and I get sporadic periods of pounding and muscle tremors in my legs, anxiety and fuzzy vision. I frequently get so cold I begin to shake. Yesterday I went back to the clinic for an EKG (normal) and some blood tests (including thyroid) and everything was normal. I am just assuming this is my body reacting and readapting itself after being on beta blockers. It has only been five days, but I am wondering if anyone out there has had similar experiences. How long did it take you to feel normal again? I ran a 5k just two weekends ago and yesterday I could hardly take a walk. Thanks for listening.

@strmalik

Hi everyone I have a question about Carvedilol I hope someone can help me with. I have taken a 3.125mg pill for about 2 weeks (maybe a little more) and I went out of town for Christmas and forgot the pills at home I was completely fine until the day after Christmas I had the worse anxiety attack i ever had right before going to bed. It was so horrible and it was not due to stress or anything so after reading some post it looks like not taking the pill has caused it. It has been almost a week since my real bad anxiety attack but between them I have had small ones and I can feel it just lingering around. Has anyone else had this happen? If so when will it stop I really thought I had to go to the hospital one night.

Jump to this post

Hello @eileena,

I’m so sorry that you are upset! You are an important part of this community and you contribute to making it welcoming. I can see that very clearly from reading your past posts on your profile page. Please allow me to clear any misunderstanding or confusion, @eileena.

I am absolutely confident that Mentor @predictable was only replying, in detail, to @shawn2018 about the effects of stopping or weaning off from Carvedilol. I acknowledge that @predictable‘s post had a cautious undertone, but that is because as a Mentor, he recognizes that Connect is about health, first and foremost.
Connect Mentors are knowledgeable, compassionate, active members in the community; they are patients, caregivers and family members who have first-hand experience with a health condition(s). Our community members should feel safe, which is why Moderators and Mentors monitor the conversations and, more importantly, rely on community members like yourself to share insights through your experiences. That is also what Connect is about.

When we consider a medication like Coreg (Carvedilol), how we start is very important. But how we stop is just as important, As you’ve mentioned in previous posts, it’s so important to taper off gradually, with help from your doctor/healthcare provider, rather than stopping abruptly to avoid any confusing, unpleasant symptoms. However, it is a well-established fact that sometimes people, myself included:( undermine common sense, get impatient with the weaning process, and decide to stop, cold turkey!
Hence, I sincerely believe that @predictable was merely ensuring that @shawn2018 had enough information, as well as emphasizing the importance of “following Dr’s orders”– and showing care and concern for a community member.
If you go to the first page of this very conversation, https://connect.mayoclinic.org/discussion/hi-everyone-i-am-glad-to-be-a-part-of-this-community/ you will see how perceptive and accurate (and cautious), both you and @predictable have been in sharing your knowledge with community members.

I hope this helps show another side of the situation, @eileena? Please keep talking, and thank you, sincerely for all your support and participation.

REPLY
@shawn2018

Hi I have been on Coreg for over a year now. Seemed to work better with less side affects then metoprolol.but after about 4 months started getting dizziness and occasionally a very sharp pain under my right rib.Last 2 months dizziness has been almost constant. Switched to toprol xl and then generic coreg(Carvedilol).No change so per doc weaned off ALL meds.I was on low dose of lisinopril. But after 4 days my hands are shaky! So now I called doc and told him via voicemail I’m going bk on. Can’t take the shaking.havent heard bk as of 5 hrs ago but will let you know. Vicious cycle these drugs!,,

Jump to this post

I have been taken coreg for about 8 months and at first I thought it was bad but my pressure goes down when I take it but I’m having some soDE effects my Johnson won’t stay up !!! I’m a young guy and can’t have that is anyone having this problem and also I finally got my adrenal glands tested cat skan and found a benign tumor on my left adrenal this may be why my pressure has been out of wack I looked it up and your adrenal glands control mostly everything in your body from hair growth to blood pressure I am going to the ecronoligist today and talk about getting it removed anyone had this problem or should I say these problems ….I’m also on clonidine, hydrolazine, and a water pill and sparalactone ……

REPLY
@shawn2018

Hi I have been on Coreg for over a year now. Seemed to work better with less side affects then metoprolol.but after about 4 months started getting dizziness and occasionally a very sharp pain under my right rib.Last 2 months dizziness has been almost constant. Switched to toprol xl and then generic coreg(Carvedilol).No change so per doc weaned off ALL meds.I was on low dose of lisinopril. But after 4 days my hands are shaky! So now I called doc and told him via voicemail I’m going bk on. Can’t take the shaking.havent heard bk as of 5 hrs ago but will let you know. Vicious cycle these drugs!,,

Jump to this post

When I got off Coreg my BP readings went up a slight bit. Coreg is a Beta Blocker and it is complicated. My Losartin was increaased in place of the beta blocker. As for your “Johnson”, lowering you BP is what causes that drooping of your guy. We need our BP lower, but maybe an adjustment in dosage? My son was found to have one of those incidentalomas on his left adrenal gland and they took the gland and tumor out and due to other health problems was kept in hospital for an overnight. It was benign as we can hope yours is. They are called incidentalomas due to being incidentally found. Don’t know what your other meds are for, but have a good discussion with you doc or look up the meds.

REPLY

So are u still off the coreg and how are u?

REPLY
@shawn2018

Hi I have been on Coreg for over a year now. Seemed to work better with less side affects then metoprolol.but after about 4 months started getting dizziness and occasionally a very sharp pain under my right rib.Last 2 months dizziness has been almost constant. Switched to toprol xl and then generic coreg(Carvedilol).No change so per doc weaned off ALL meds.I was on low dose of lisinopril. But after 4 days my hands are shaky! So now I called doc and told him via voicemail I’m going bk on. Can’t take the shaking.havent heard bk as of 5 hrs ago but will let you know. Vicious cycle these drugs!,,

Jump to this post

@krj1213, glad to hear that you’re going to see an endocrinologist today, and I hope you will consider a longer list of questions than whether to have a benign tumor removed from your adrenal gland. Do I understand that your current medication load includes five different medications for treating high blood pressure — Coreg (Carvedilol), Clonidine, Hydralazine, Spironolactone, and an unnamed “water pill?” You and I have a lot in common (with this exception): My medical team never suggested that I take more than three antihypertensive medications at one time.

I also have a tumor on one adrenal gland, and the key question for my nephrologist and my endocrinologist was whether the tumor was, in fact, acting as a rogue gland-in-the-wild, producing excess hormones that inflate blood pressure. Lab tests showed that it probably was NOT a rogue gland, but simply a cyst, discovered by accident by an MRI a few years ago. Since then, we check it for any change in size or composition — so far, no change.

Of the five medications you listed, I have been on all of them at one time or another. Right now, my daily meds include Coreg (25mg x 2), Amiloride (10mg x 2, potassium-sparing water pill), and Lisinopril (40mg x 1, a vasodilator relaxing arteries). In the past, I also took Clonidine (centrally acting with hormones issued from the brain), and Spironolactone, a powerful diuretic (water pill). The fifth med, Hydralazine, is a vasodilator (relaxing arteries) similar in effect to my Lisinopril and, several years ago, to Minoxidil.

Against that background, I know you will understand the importance of a detailed conversation with your medical team about why a half-dozen medications are suitable for treating your personal symptoms. In my case, an endocrinologist was crucial to testing for every conceivable cause of my high blood pressure, but my real angel is the leader of my medical team — a nephrologist, whose genius and persistence found the source of my problems and eliminated the excess medications I had taken.

Let me know of any questions you have about my experiences or about talking to your own medical team. And remember, one question on your mind when you meet with them might be whom they would recommend to give you a second opinion later this month. Martin

REPLY

I am having severe dizziness and my cardiac doctor thinks it might be my pills. My BP got done to 55/45 and so I stopped my Valsartan but Monday he told be to also stop my Coreg CR 20 too. In the mornings I get good BP about 100/70 but by bedtime it goes up to (just now) 148/84. Seems like a lot to go up over the day. Based on my Omron BP786N. I'm thinking I need to start again on something to keep it in a good range all day. All suggestions? Not doing the Coreg is helping the dizziness but the higher BP makes me nervous. It's a few months to see him again and I'm wondering if I need to go back for an adjustment sooner.

REPLY

There is a lot of good advice in the response by "predicable" for all of us dealing with hypertension. I have found that since I changed my primary care doctor, who is more open to discussions, and who suggested I stop taking the Lisinoprol because it made me so dizzy. So now I only take 1 Atenolol 25mg daily. He suggested that under 140/90 is acceptable for a person of my age.

Since then I have been experimenting using pure ginger tea and dried ginger and now have added 2 1/4 tablespoons of pure beet juice (bottled) in the morning during the last couple of days. Yesterday the systolic range was in the 120's most of the day. I don't suggest anyone else try the beet juice and I did a lot of research on the Internet about the latest blind studies results that show positive results in using beet juice for hypertension although there can be some side effects that should be checked out (information on the Internet) before experimenting with beet juice.

REPLY

Thank you, @predictable.

Hello @terryzx,
You may notice that I moved your discussion and combined it with this existing conversation on high blood pressure, Coreg, and side effects. I did this as I thought it would be beneficial for you to be introduced to the many members who have discussed much of what you are experiencing.
If you click on VIEW & REPLY in your email notification, you will see the whole discussion and can join in, meet, and participate with other members talking about their or their loved ones' experiences.

Martin has provided some excellent insights, and I'm confident @eileena @zany @randypape and others will return with their suggestions.
This Mayo Clinic link, https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/expert-answers/blood-pressure/faq-20058115 has some excellent information and expert answers, with regard to blood pressure readings, and daily pattern changes.

REPLY
@terryzx

I am having severe dizziness and my cardiac doctor thinks it might be my pills. My BP got done to 55/45 and so I stopped my Valsartan but Monday he told be to also stop my Coreg CR 20 too. In the mornings I get good BP about 100/70 but by bedtime it goes up to (just now) 148/84. Seems like a lot to go up over the day. Based on my Omron BP786N. I'm thinking I need to start again on something to keep it in a good range all day. All suggestions? Not doing the Coreg is helping the dizziness but the higher BP makes me nervous. It's a few months to see him again and I'm wondering if I need to go back for an adjustment sooner.

Jump to this post

Hello and Welcome, @bimbus1,

May I ask what brings you to Connect? We look forward to hearing from you.

REPLY

Thank you all for your replies. I know that my higher BP before bed is not horrible and some say acceptable for my age 70. However, the older I get the more I want to be in "THE ZONE" of 80/120 as so may studies suggest it's much safer there than higher.

I was in that zone for several years before but now I started getting too low with BP hitting 55/45 and so stopped my Valsartan. But this still left my pulse in the low 50's and ever mores I've been getting horrible dizzy spells. In fact I was trying to cut the grass last week and fell an smacked my face into a brick and ha to go to the ER and they did several CAT Scans. Wasn't serious "this time" but I was strongly cautioned that it could have severely injured or killed me it I hit other than my jaw.

I expressed my concern over this escalating dizziness to my cardiologist and so he stopped the Coreg CR 20 which I feel is the culprit doing that. I already stopped the Valsartan myself 6 weeks ago and he agreed that was good. He said he wanted to get all the drugs out of my system and then set me up with a Nuclear Stress for tomorrow and next month a visit with a Electrophysiology guy he called his "electrician".

That being because of a variance in my left and right arm BP both from one side to the other and from sitting to standing position.

This all kinna worries me as the older I get, the more I want to keep getting older….

I tend to think that this is all the fault of the Coreg CR 20. He had me stop starting Tuesday "cold turkey" and I mentioned about stopping suddenly. He tells me that the Coreg CR 20 is not all that much and it would be fine.

I'm thinking that this is the reason for the end of day spikes. But on the other hand, just these few days off, that dizziness is much less noticeable. I'm just concerned about being out of the good 80/120 that I was in. Also each morning I wake up and check and I am lost always about 100/60 or around that range. That is why I wonder my bp is spiking near 40points by the end of the day. Must be that Coreg I bet.

I know that for my age 140/80 is not so bad…or so they say. But getting older makes me feel like I need to be 80/120.

Also when I used Valsartan I was eating a LOT more on a high fat low carb diet for my diabetes. But when I went on an under 1500 calorie a day binge as I am now, my BP just plummeted when resulted in my stopping Valsartan 160. That was working great when eating a whole lot more, but I still had that horrible dizziness that caused me to fall numerous times.

I might be able to get back on the Valsartan 160's again, as those ARB's gave me no problems. Allergic to ACE.

This Electrophysiology guy is in the top 5% of doctor's ratings so I hope he can help find something besides a beta blocker that will do the job.

REPLY

Dena before my by pass surgery my Cardiologist put me on Coreg one night is all I took the next themes s and some other did effects where crazy,panic attacks ,anxiety ,he took me of right away I wasn't on that long but it will take your body time to reajust drink pl e th of water to clear your system My by pass is ,22 yrs old now I'm 75 ,good luck

REPLY
@ladybugmg

There is a lot of good advice in the response by "predicable" for all of us dealing with hypertension. I have found that since I changed my primary care doctor, who is more open to discussions, and who suggested I stop taking the Lisinoprol because it made me so dizzy. So now I only take 1 Atenolol 25mg daily. He suggested that under 140/90 is acceptable for a person of my age.

Since then I have been experimenting using pure ginger tea and dried ginger and now have added 2 1/4 tablespoons of pure beet juice (bottled) in the morning during the last couple of days. Yesterday the systolic range was in the 120's most of the day. I don't suggest anyone else try the beet juice and I did a lot of research on the Internet about the latest blind studies results that show positive results in using beet juice for hypertension although there can be some side effects that should be checked out (information on the Internet) before experimenting with beet juice.

Jump to this post

It is great your BP is coming under control.

I have added some other supplements to my daily regimen. I learned that the 3 building blocks for ATP are ribose, L-Carnitine, and CoQ10. ATP is necessary for heart health and sometimes we cannot produce enough on our own and thus need to supplement those building blocks. I also take, with my cardiologist's permission I will add, some Hawthorne Solid Extract.

Please do consult with your doctor before trying these on your own. Coreg kept my heart rate suppressed, and that drove my BP up. It took months for me to wean off the stuff, but I did have my doctor's advise and permission. I began to really feel much better after getting off the Coreg.

My advise, go slowly and reduce your dose over as long a period of time as it takes. Do not get in a hurry as it can cause you problems you just don't want to deal with.

Best of luck.

Liked by thankful

REPLY

Yesterday I went in an did a Nuclear Stress Test.
Went very well.
In 2005 I had a stent implanted which up until now I had thought was from a 90% blocked artery. Now he tell me that I actually I heart attack then. It was lucky that I was feeling weird and went to the ER where I had to get surgery right away and was hospitalized for a week. Now I hear that it was a 100% blockage and there is a little scar tissue an was lucky to have driven myself there in time.

Everything looked great and my BP was in the good 80/120 range the entire time and without any drugs.

When I got home and checked it again I was still in the zone.
I decided to skip my own treadmill yesterday an wen I checked my BP before be it was still good.
So now I see that the spike I was getting appears to be from using the treadmill.
It's odd that after over 3 hours my BP remained elevated…but after just 3 hours sleep it dropped back to normal.

At least now I know what was causing the spike.

Still going to the doctor my cardiologist referred me to for a variance in my left and right arm BP both from one side to the other and from sitting to standing position.

Still off that miserable Coreg CR an my dizziness is a lot less…also the tinnitus I've had for years has gone away. I'm pretty sure that the Coreg CR was also using that too.

REPLY

I am in Carvedilol 3.125mg. I am taking it once a day. I want to get off of it completely. I have never had high blood pressure. I had double bypass last year. I’m wanting to go off and do a more natural beta blocker method. Such as foods, supplements, and vitamins. Can I quit my morning tablet completely?

REPLY

I have only taken Carvedilol 6.25 for 20 days. I had to stop due to anxiety, pounding heart, coughing, sweating and the feeling of fear and panic. Which I have never experienced before! Will I have a problem from stopping the Med. This is my second day off. The cough is horrible but I don’t feel the panic I was experiencing. Called my PC unable to get in. They suggested walk-in Clinic. My BP is higher on the med than off. I feel I need to wait for PC. I am hoping for input from someone with similar experience.

REPLY
Please login or register to post a reply.