Anybody experiencing both at the same time?
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Hello All, I am still battling HER2 + and HER2- at the same time the + appears to be responding to Herceptin and Perjeta. I started Piqray for the negative about 45 days ago & will know soon if it is getting the HER2 negative under control. Please let me know if anybody else has both a negative and a positive going on at the same time. Thanks
I am now taking Arimidex.
Unfortunately Arimidex did not work as well as I expected for me.
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I wish you every luck with your treatment and keep on fighting,💕💓
I was just recently (July) diagnosed with both. My left breast tumor is HER2- but my lymph nodes are HER2+ I have a small cancerous lesion on my left pelvic bone. I am not sure what type it is yet. I just had my first round of (six scheduled) chemo treatments a week ago. I am taking Taxotere, Carboplatin, Herceptin, Perjeta and Neulasta. I will have surgery after I finish chemotherapy.
The pelvic bone lesion is something which I worry about (bone lesions in general)… at my age, so many places hurt. How did you discover it? What were your symptoms, if you don't mind me asking?
Oh my, you sure have a lot to deal with. I had two lesions in my breast but both were ER/PR+ and HER2- and was on taxotere and carboplatin, not all the extras you are receiving. Just recently though on PET scan a very small lesion was noted in my lung which they'll watch and do another PET scan in 3 months. Here's to all of your infusions going well. All the best to you.
WOW….. I hope you read my initial post. But just to quickly recap, I was diagnosed in April 2015 with HR+HER2- invasive ductile carcinomas. 2 surgeries/8 rounds of chemo/33 rounds of radiation and then declared NED until August 2019 when it came back in my chest. We thought it was negative & started Ibrance but about 30 days in we discovered it was HER2+…..& switched to Herceptin/Perjeta with a Faslodex shot. But in Jan 2020 we discovered lesions in my neck/spine that turned out to be HER2-. (My neck fractured… which resulted in 10 rounds of radiation & a very restrictive neck brace from 01/25-06/29)
It appears the + is responding well to Herceptin/Perjeta/Faslodex. The – is a bit more stubborn. I started Piqray in May, I am into round 3 of the Piqray and it appears it might be working 🙏🏽Scheduled to check my tumor marker again in about 3 weeks. If it’s going down we will stay with Herceptin/Perjeta/Faslodex/Piqray. I remain optimistic and faithful. This journey requires a positive attitude always…..otherwise cancer wins . Don’t give in….. Don’t give up….. Don’t give out!
You can do this! Stay strong!
My daughter was 23 when she was first diagnosed with HER2 negative breast cancer in Nov of 2018. Had a lumpectomy right away, followed 4 rounds of chemo and 30+ rounds of radiation. Then in April of this year 2021 she was diagnosed with HER2 positive, same breast, different area, and a bone biopsy determined it's stage 4 cancer. She's having chemo #6 next week (in addition to the immunotherapy – herceptin/projetta). We do not have a history of breast cancer in my family, and her genetic markers are negative for the breast cancer gene. It's really terrible, I wish so much this wasn't happening to her.
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