Forteo vs. Tymlos

Posted by suze317 @suze317, Oct 17, 2018

I have to make a decision on Forteo vs. Tymlos and am not sure what to choose. Forteo has been around a lot longer, but has to be refrigerated. Tymlos only around 1 1/2 years but is shelf stable and seems to have less side effects and less issues with calcium. Can anyone offer their perspective? Thank you!

@suerc

I have osteopenia. The start of osterperosis. It runs in the family. Grandmother had it , and my mom has it. I think genetics has some to do with it. I was on prolia for a few yrs and bones did well. Then my Dr retired. And I had no one to go to. Now I have a new Dr. My t score dropped a little in the 2 yrs I didn't see anyone. So now they want to prevent it from getting worse. I am taking Diet do. Only side affect so far is a terrible headache. I have been on it for 1 week so will see if it goes away.

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Also injecting is not bad at all.

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@suerc

I have osteopenia. The start of osterperosis. It runs in the family. Grandmother had it , and my mom has it. I think genetics has some to do with it. I was on prolia for a few yrs and bones did well. Then my Dr retired. And I had no one to go to. Now I have a new Dr. My t score dropped a little in the 2 yrs I didn't see anyone. So now they want to prevent it from getting worse. I am taking Diet do. Only side affect so far is a terrible headache. I have been on it for 1 week so will see if it goes away.

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@suerc Ive had Osteopenia for along time also Im glad the medicine helps you and everyone that it helps .I choose to just take my Vit-Mineral med and exercise so far so good 👍.

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@lioness

@suerc Ive had Osteopenia for along time also Im glad the medicine helps you and everyone that it helps .I choose to just take my Vit-Mineral med and exercise so far so good 👍.

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@lioness I wish you well with this. I hate having to take these types of meds.

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@seurec what is diet do? I hate it when I have to look for a new doctor! Please let me know how you fare and if your headache s go away.

Liked by lucky1038

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I am 63 years old with a kidney transplant. I have 1-1/2 year of my transplant operation. I have a very bad osteoporosis, and my doctor recommend Tymlos but I could not tolerate this medicine . Too much side effect. Now the doctor recommend Forteo. I have using this med in injection for 1-1/2 week . I can tolerate this med better . I have only a little pain in my back for seconds and goes away. I am glad I want to rebuild my bones again.

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@kanaazpereira

Hello @leacy,

You're correct in that Tymlos (Abaloparatide) is the newest osteoporosis medication. According to Mayo Clinic, "Like teriparatide (Forteo), it has the potential to rebuild bone. In a research trial comparing these two treatments, abaloparatide appeared to be as effective as teriparatide but was less likely to cause an excess of calcium." https://www.mayoclinic.org/diseases-conditions/osteoporosis/in-depth/osteoporosis-treatment/art-20046869
More details about Tymlos can also be found here: https://www.mayoclinic.org/drugs-supplements/abaloparatide-subcutaneous-route/description/drg-20406221

I'm tagging @gdaniels138 @lynnes @dolan @kevinking @rannie @jojojo @rnwholovedtowork, as they might have more insights to share with you.
I would also encourage you to go through this incredibly informative discussion on Connect:
– Treating osteoperosis https://connect.mayoclinic.org/discussion/hi-im-new-to-the-site-and-am-interested-in-treating-osteoperosis/

@leacy, may I ask what treatments you've tried so far?

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I’ve just been diagnosed with osteoporosis. Age 59. Male. Unfortunately took significant prednisone which led to a bone density test (results -3.2 hip, wrist. -2.9 spine.). Dr strongly recommended immediate bone regeneration medication. Due to my job (extensive travel) Tymlos was suggested. Not worried about giving daily shots but highly concerned about side effects that will effect quality of live and dealing with them while overseas. In particular, dizziness and headaches. Getting 2nd opinion next week (suspect it will be similar). Grateful for input on severity of side effects.

Liked by lucky1038

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@denvergary

I’ve just been diagnosed with osteoporosis. Age 59. Male. Unfortunately took significant prednisone which led to a bone density test (results -3.2 hip, wrist. -2.9 spine.). Dr strongly recommended immediate bone regeneration medication. Due to my job (extensive travel) Tymlos was suggested. Not worried about giving daily shots but highly concerned about side effects that will effect quality of live and dealing with them while overseas. In particular, dizziness and headaches. Getting 2nd opinion next week (suspect it will be similar). Grateful for input on severity of side effects.

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I understand your concerns about side effects of Tymlos or Forteo..But studies have shown that not treating your osteoporosis is much worse..The benefits outweigh the risks..For instance the biggest problem I had was the one side effect of osteiocarcinoma, in short, bone cancer..I believe that only one human got that, but she had cancer & radiation at a time in her life..they pretty much linked it to that..Another thing, is don't smoke..your ruining your chances of building bone at all! I have been injecting Tymlos for 2 months now, the side effects are mild..the only one I experienced is a headache for the first 3 or 4 days (not a migraine) and a slightly rapid heartbeat…you just feel a little hyper but it didn't slow me down…The injections are a piece of cake..takes me 5 minutes and done. My osteoporosis is in my lower lumbar….a second opinion is good, but probably will be the same recommendation…mine is not genetic, it's probably due to dieting etc during my 30's 40's, trying to have that perfect body…I wish you luck with everything!

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I am 59 was a runner and trained with weights most of my life. I found out I have severe osteoporosis 2.8 in hips 3.6 in spine and 4 in forearm. The radiologist misread my scan 2 years ago and said I had osteopenia. In the past year I had spinal fusion surgery and am still recovering. I’m sure the steroid meds I was given for my back made the scans even worse. My doctor wants me to use Tymlos. The side effects sound horrible and I already live with weekly migraines and nausea from that. The doctor told me osteoporosis is 85% genetic and both my mother and grandmother had it. I am trying to find an alternative to Tymlos and am looking into Algacal, they guarantee your bone scans to increase. Has anyone heard of this working avoiding the drugs.

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@electii: There are Facebook groups that deal with this subject. I am skeptical since their money back guarantee is only if you do the dexa right before starting algaecal which many people don't.

Liked by lucky1038

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For those of your taking Calcium, Magnesium and DS-3, please add Vitamin K2 (MK7form) to your list of supplements. "For Healthy Bones. Research has shown that Vitamin K2 is one of the most important nutrients for long-term bone health and that it is even more important than calcium. K2 is needed to help calcium and other minerals bind into the bone matrix to strengthen bones (and not to stay in soft tissue where it can cause calcification in the wrong places). In fact, studies have shown that Vitamin K is effective at not just stopping bone loss in people with osteoporosis but potentially reversing it as well."

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@electii

I am 59 was a runner and trained with weights most of my life. I found out I have severe osteoporosis 2.8 in hips 3.6 in spine and 4 in forearm. The radiologist misread my scan 2 years ago and said I had osteopenia. In the past year I had spinal fusion surgery and am still recovering. I’m sure the steroid meds I was given for my back made the scans even worse. My doctor wants me to use Tymlos. The side effects sound horrible and I already live with weekly migraines and nausea from that. The doctor told me osteoporosis is 85% genetic and both my mother and grandmother had it. I am trying to find an alternative to Tymlos and am looking into Algacal, they guarantee your bone scans to increase. Has anyone heard of this working avoiding the drugs.

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@electii I have completed over 12 months on Tymlos, and like you, have had migraine all my adult life. Drug reactions and multiple allergies have been ongoing issues for me. Perhaps my experience might be helpful. I suffered a compression fracture of the L4 two years ago, and it became shockingly clear that I, an active high altitude hiker, had severe osteoporosis. ( spine 4, hip 3.5 ). If I hoped to regain an active life, something had to be done. My endocrinologist prescribed Forteo. Two weeks later I had to stop Forteo due to an allergic reaction. Providentially, at that time, Tymlos had just come on the market. It felt reckless to try such a new drug, but I did. Nearly 13 months later, I am successfully tolerating Tymlos. I had a mild headache (not migraine) for a few days after starting Tymlos. Now, I have a bit of fatigue, and for a short time after the injection I am aware of my pulse. The best side effect was evident when I had a DEXA after 5 months. I had a profound increase in bone density. I am so thankful, and glad I did not give in to my fears. I totally understand the devastation and fear that drug reactions bring. I hope to complete two years with Tymlos. I send my best to you and hope you will soon be running again.

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@leacy

I’m 59, with osteoporosis, primarily in my spine, 3.4 t-score in spots. I’ll begin a daily injectable soon, it’s called Tymlos. If I understand correctly, it’s the newest version of daily injectable. Does anyone have any experience with this med? The results for other daily injectables sound good. Side effects?

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Hello, I'm brand new to this group. I was diagnosed yesterday with severe osteoporosis in my lower back AND R.A. I'm a dental hygienist and went to my MD when my right hand started to hurt. I was referred to a rheumatologist for a blood marker for RA and she discovered my osteoporosis on my last several dexa scans that were not read correctly and the diagnosis was missed!! So she suggested Tymlos. She said that my insurance does not cover it. My question is, how do I get Tymols? I have read online that the manufacturer sometimes gives a discount… how does one qualify? She said that Reclast would be my second choice. My R.A, is slight, and right now, is the least of my worries

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@lisainfl

Hello, I'm brand new to this group. I was diagnosed yesterday with severe osteoporosis in my lower back AND R.A. I'm a dental hygienist and went to my MD when my right hand started to hurt. I was referred to a rheumatologist for a blood marker for RA and she discovered my osteoporosis on my last several dexa scans that were not read correctly and the diagnosis was missed!! So she suggested Tymlos. She said that my insurance does not cover it. My question is, how do I get Tymols? I have read online that the manufacturer sometimes gives a discount… how does one qualify? She said that Reclast would be my second choice. My R.A, is slight, and right now, is the least of my worries

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@lisainfl I am 60 yrs old and have similar spine score and also slight osteoporosis in my hips. My endocrinologist pretty much gave me the option of reclast, prolia or tymlos. I felt maybe the tymlos would work a little faster and then I could follow with reclast to lock in the new bone. The doctor knows the protocol for the approval process. I believe each insurance company is different on what they approve and how easily. I cannot take oral bisphosonates because I already have esophagus irritation. My endo said the approval will take about a month, which surprised me but maybe that's the longest time. I think they know that questions come back and sometimes the insurance suggests cheaper options to try first and then your doctor needs to justify the use. I would ask your doctor about the approval. I am curious if your doctor said why she chose Tymlos as first line of defense – I always like to compare what different doctors choose and why. Thank you, and good luck!

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@kdbones

@lisainfl I am 60 yrs old and have similar spine score and also slight osteoporosis in my hips. My endocrinologist pretty much gave me the option of reclast, prolia or tymlos. I felt maybe the tymlos would work a little faster and then I could follow with reclast to lock in the new bone. The doctor knows the protocol for the approval process. I believe each insurance company is different on what they approve and how easily. I cannot take oral bisphosonates because I already have esophagus irritation. My endo said the approval will take about a month, which surprised me but maybe that's the longest time. I think they know that questions come back and sometimes the insurance suggests cheaper options to try first and then your doctor needs to justify the use. I would ask your doctor about the approval. I am curious if your doctor said why she chose Tymlos as first line of defense – I always like to compare what different doctors choose and why. Thank you, and good luck!

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My doctor chose Tymlos because it works in 18 months and doesn’t require refrigeration like Forteo

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@electii

My doctor chose Tymlos because it works in 18 months and doesn’t require refrigeration like Forteo

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@lisainfl So she thought it worked better than Reclast? Mine had said as for as fracture prevention they were about equal after 1 year – despite any comparative BMD. It was a tough decision for me. I will likely do 1 year then follow with a year or two with Reclast. Save the second year since we only get 2 years lifetime use. Thanks for sharing!

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