Forteo vs. Tymlos

Posted by suze317 @suze317, Oct 17, 2018

I have to make a decision on Forteo vs. Tymlos and am not sure what to choose. Forteo has been around a lot longer, but has to be refrigerated. Tymlos only around 1 1/2 years but is shelf stable and seems to have less side effects and less issues with calcium. Can anyone offer their perspective? Thank you!

Now this sounds promising! Thank you Bonnie

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@merpreb

Hello- I am new on this discussion as of today. I needed to stop Fosamax because of horrible upper stomach cramps, throat spasms, etc. I can't take any other pill forms-I have tried the once a month pill (forgot the name). I have broken bones so I really need something. I also stopped going to a rheumatologist because I can never get an appointment when I needed one so I'll use my pcp. Any suggestions? I'm petrified of the shots' side effects. Thank you

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@merry with all the horrible comments about fosamex,prolia,reclast ,why dont you just exercise ,water aerobics weights, .My girlfriend has osteoporosis Dr put her on Vitamin D3 calcium and magnesium told her to exercise its been 10 yrs but she can walk and had no side effects .

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@lioness– I do exercise. I also take extra D3, and calcium and mag. I'm petite and it runs in the family. Your friend is lucky, but I fear that all that good stuff isn't appropriate for everyone. I wish it were!

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@merpreb

@lioness– I do exercise. I also take extra D3, and calcium and mag. I'm petite and it runs in the family. Your friend is lucky, but I fear that all that good stuff isn't appropriate for everyone. I wish it were!

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@merpreb Sorry to hear maybe genes play a part in it?I don't know but there's alot we don't know Didn't mean to offend anyone.

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@lioness– I'm not offended at all. You're right, there is a lot that we don't know

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@lioness

@merry with all the horrible comments about fosamex,prolia,reclast ,why dont you just exercise ,water aerobics weights, .My girlfriend has osteoporosis Dr put her on Vitamin D3 calcium and magnesium told her to exercise its been 10 yrs but she can walk and had no side effects .

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I have osteopenia. The start of osterperosis. It runs in the family. Grandmother had it , and my mom has it. I think genetics has some to do with it. I was on prolia for a few yrs and bones did well. Then my Dr retired. And I had no one to go to. Now I have a new Dr. My t score dropped a little in the 2 yrs I didn't see anyone. So now they want to prevent it from getting worse. I am taking Diet do. Only side affect so far is a terrible headache. I have been on it for 1 week so will see if it goes away.

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@suerc

I have osteopenia. The start of osterperosis. It runs in the family. Grandmother had it , and my mom has it. I think genetics has some to do with it. I was on prolia for a few yrs and bones did well. Then my Dr retired. And I had no one to go to. Now I have a new Dr. My t score dropped a little in the 2 yrs I didn't see anyone. So now they want to prevent it from getting worse. I am taking Diet do. Only side affect so far is a terrible headache. I have been on it for 1 week so will see if it goes away.

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Also injecting is not bad at all.

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@suerc

I have osteopenia. The start of osterperosis. It runs in the family. Grandmother had it , and my mom has it. I think genetics has some to do with it. I was on prolia for a few yrs and bones did well. Then my Dr retired. And I had no one to go to. Now I have a new Dr. My t score dropped a little in the 2 yrs I didn't see anyone. So now they want to prevent it from getting worse. I am taking Diet do. Only side affect so far is a terrible headache. I have been on it for 1 week so will see if it goes away.

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@suerc Ive had Osteopenia for along time also Im glad the medicine helps you and everyone that it helps .I choose to just take my Vit-Mineral med and exercise so far so good 👍.

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@lioness

@suerc Ive had Osteopenia for along time also Im glad the medicine helps you and everyone that it helps .I choose to just take my Vit-Mineral med and exercise so far so good 👍.

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@lioness I wish you well with this. I hate having to take these types of meds.

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@seurec what is diet do? I hate it when I have to look for a new doctor! Please let me know how you fare and if your headache s go away.

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I am 63 years old with a kidney transplant. I have 1-1/2 year of my transplant operation. I have a very bad osteoporosis, and my doctor recommend Tymlos but I could not tolerate this medicine . Too much side effect. Now the doctor recommend Forteo. I have using this med in injection for 1-1/2 week . I can tolerate this med better . I have only a little pain in my back for seconds and goes away. I am glad I want to rebuild my bones again.

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@kanaazpereira

Hello @leacy,

You're correct in that Tymlos (Abaloparatide) is the newest osteoporosis medication. According to Mayo Clinic, "Like teriparatide (Forteo), it has the potential to rebuild bone. In a research trial comparing these two treatments, abaloparatide appeared to be as effective as teriparatide but was less likely to cause an excess of calcium." https://www.mayoclinic.org/diseases-conditions/osteoporosis/in-depth/osteoporosis-treatment/art-20046869
More details about Tymlos can also be found here: https://www.mayoclinic.org/drugs-supplements/abaloparatide-subcutaneous-route/description/drg-20406221

I'm tagging @gdaniels138 @lynnes @dolan @kevinking @rannie @jojojo @rnwholovedtowork, as they might have more insights to share with you.
I would also encourage you to go through this incredibly informative discussion on Connect:
– Treating osteoperosis https://connect.mayoclinic.org/discussion/hi-im-new-to-the-site-and-am-interested-in-treating-osteoperosis/

@leacy, may I ask what treatments you've tried so far?

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I’ve just been diagnosed with osteoporosis. Age 59. Male. Unfortunately took significant prednisone which led to a bone density test (results -3.2 hip, wrist. -2.9 spine.). Dr strongly recommended immediate bone regeneration medication. Due to my job (extensive travel) Tymlos was suggested. Not worried about giving daily shots but highly concerned about side effects that will effect quality of live and dealing with them while overseas. In particular, dizziness and headaches. Getting 2nd opinion next week (suspect it will be similar). Grateful for input on severity of side effects.

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