Evusheld Update

Posted by joko @joko, Aug 11, 2022

Thanks everyone on here for info on Evusheld and sharing experiences with the AstraZeneca monoclonal antibodies injections. I was listed on the University of Wisconsin Transplant list lottery, but used the website https://covidsafe.fyi/evusheld/ to check on my county, Door, to see that we didn't have any doses. Contacted them and they ordered some. Yesterday I got the two injections and have had no reactions. Just to share with others who are wondering about Evusheld. About price. My Medicare Advantage insurer checked and it was $0.50 out of pocket. Probably because the Feds bought 1.7 million doses and must be subsidizing. Hope this is helpful.

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@hello1234

Hi all,
I just read an article that the effectiveness of both Evusheld and the bebtelovimab monoclonal antibodies infusion is waning. The current monoclonal antibodies are not neutralizing some of the new covid subvariants. It sounds like we need to be extra careful and go back to the basics.

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Although I am not a scientist or a researcher, I am aware that the Covid19 – SARS is known to be constantly changing. I am not surprised or shocked to hear this update.

– Update [10/3/2022] FDA added important information to the authorized Fact Sheets for Evusheld (tixagevimab co-packaged with cilgavimab) to inform health care providers and individuals receiving Evusheld of the increased risk for developing COVID-19 when exposed to variants of SARS-CoV-2 that are not neutralized by Evusheld.

Here is the link to the FDA site, so you can read the latest update
-Latest FDA Updates for Evusheld
https://www.fda.gov/drugs/drug-safety-and-availability/fda-releases-important-information-about-risk-covid-19-due-certain-variants-not-neutralized-evusheld

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@hello1234

Hi all,
I just read an article that the effectiveness of both Evusheld and the bebtelovimab monoclonal antibodies infusion is waning. The current monoclonal antibodies are not neutralizing some of the new covid subvariants. It sounds like we need to be extra careful and go back to the basics.

Jump to this post

My oncologist made the similar comment to me yesterday.. My next dose is due in February. He said we'll see where things are at that point.
Ginger

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@hello1234

Hi all,
I just read an article that the effectiveness of both Evusheld and the bebtelovimab monoclonal antibodies infusion is waning. The current monoclonal antibodies are not neutralizing some of the new covid subvariants. It sounds like we need to be extra careful and go back to the basics.

Jump to this post

I got Evusheld in October and got Covid a week ago. The team at Mayo set me up for Remdesivir instead of the monoclonal antibodies because they were seeing no improvement with antibodies recently. Just switched the protocol 2 weeks ago. I’m feeling better now. I had been so careful for so long that I couldn’t believe I got it! Just down for about a week and I seem to be on the mend now. Hopefully this will be a one and done experience!

REPLY
@hello1234

Hi all,
I just read an article that the effectiveness of both Evusheld and the bebtelovimab monoclonal antibodies infusion is waning. The current monoclonal antibodies are not neutralizing some of the new covid subvariants. It sounds like we need to be extra careful and go back to the basics.

Jump to this post

Mayo wants me to take Evusheld every 6 months. So Mayo sent me a reminder message. After my PCP team found the correct forms for those ummune suppressed a local hospital's infusion center just gave me my second round. My county is having a surge in COVID cases.

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@mollyv

I got Evusheld in October and got Covid a week ago. The team at Mayo set me up for Remdesivir instead of the monoclonal antibodies because they were seeing no improvement with antibodies recently. Just switched the protocol 2 weeks ago. I’m feeling better now. I had been so careful for so long that I couldn’t believe I got it! Just down for about a week and I seem to be on the mend now. Hopefully this will be a one and done experience!

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Hi @mollyv 😊
I am happy to hear that you are now on the mend and feeling better after covid! Thank you so much for telling me about Remdesivir as the brand new protocol replacement to the monoclonal antibodies infusion. Did you have a kidney or liver transplant?

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@hello1234

Hi @mollyv 😊
I am happy to hear that you are now on the mend and feeling better after covid! Thank you so much for telling me about Remdesivir as the brand new protocol replacement to the monoclonal antibodies infusion. Did you have a kidney or liver transplant?

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@hello1234 I had a kidney transplant 11 years ago. I read in the paper today that Evusheld is not effective with current strains. I’m hoping that the fact that I’ve had Covid now, that I’ll be protected at least through the holidays. I’ve been so careful and have missed so many things these past few years. Fingers crossed for a somewhat freer month! I hope everyone else is doing well!

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@mollyv

@hello1234 I had a kidney transplant 11 years ago. I read in the paper today that Evusheld is not effective with current strains. I’m hoping that the fact that I’ve had Covid now, that I’ll be protected at least through the holidays. I’ve been so careful and have missed so many things these past few years. Fingers crossed for a somewhat freer month! I hope everyone else is doing well!

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Hi @mollyv 😊
I am a two year post kidney transplant patient. My story is the same as your story, but I received the bebtelovimab monoclonal antibodies infusion back in October instead of Remdesivir as my treatment.
Is Remdesivir a single infusion? Is it a full IV bag that takes several hours to drip in or a single shot in the IV? Did you feel better pretty quickly after the treatment?
I caught covid in October after being mega careful. These new variants are everywhere and super contagious!

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@mollyv

I got Evusheld in October and got Covid a week ago. The team at Mayo set me up for Remdesivir instead of the monoclonal antibodies because they were seeing no improvement with antibodies recently. Just switched the protocol 2 weeks ago. I’m feeling better now. I had been so careful for so long that I couldn’t believe I got it! Just down for about a week and I seem to be on the mend now. Hopefully this will be a one and done experience!

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I had Covid 1 month ago and Im Immunocompromsed . All it was is a sore throat,fatigue, and a runny nose with low grade fever 100.1 . Gone in 5 days . No long Covid. We were blessed with Omnicron!

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@hello1234

Hi @mollyv 😊
I am a two year post kidney transplant patient. My story is the same as your story, but I received the bebtelovimab monoclonal antibodies infusion back in October instead of Remdesivir as my treatment.
Is Remdesivir a single infusion? Is it a full IV bag that takes several hours to drip in or a single shot in the IV? Did you feel better pretty quickly after the treatment?
I caught covid in October after being mega careful. These new variants are everywhere and super contagious!

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@hello1234 the Remdesivir is an infusion given over three days. It takes less than an hour each time and is given at an infusion center, outpatient. Other than having to leave the house when I didn’t feel well, it was pretty easy. I didn’t really notice it working, but I feel so much better now – 3 days post infusion.

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@hello1234

Hi all,
I just read an article that the effectiveness of both Evusheld and the bebtelovimab monoclonal antibodies infusion is waning. The current monoclonal antibodies are not neutralizing some of the new covid subvariants. It sounds like we need to be extra careful and go back to the basics.

Jump to this post

Thank you @mollyv for the very helpful details about the Remdesivir treatment! I always like to have a heads up about what to expect. 😊
Other than covid, how are things going with your kidney transplant? I love to hear when someone is 11 years post kidney transplant! I am two years post kidney transplant (deceased donor) and currently waiting for my BK virus to resolve. Things are going very well for me with just a couple hiccups like CMV and BK. My kidney function is good so I am thrilled. ❤

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