Have you received warning about Paxlovid from your transplant team?

Posted by bildad @bildad, Jan 10, 2022

I just received a warning from my liver transplant team concerning Paxlovid. It’s a Covid treatment drug from Pfizer. If one is taking immunosuppressants then Paxlovid is a no no. Ha y’all been warned about this?

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I am not familiar with Paxlovid but I wanted to comment on a couple of other things that are being discussed in this conversation.

My personal suspicion is that if you are fairly recently transplanted then you are on a higher dose of immunosuppressants so will probably have fewer antibodies from the vaccines. I am 5.5 years out. After 3 shots my antibody count was 2032 U/ml which I think is fairly good. I also had it tested after my second shot and then it was only 13.82 so the third shot made a huge difference. My transplant team keeps my immunosuppressant as close to the lower end of the range as possible. I have had no problems.

Omicron is generally less severe than Delta but that is especially true for those of us who are fully vaccinated. The hospitals are at near capacity or close to it due to Omicron and patients who are not fully vaccinated. In my town, the students are still in school but the absenteeism with the students and with the teachers is extremely high. The schools seem to be real hotbeds of Covid.

I am at the point where I can get the booster - the protocol for immunocompromised patients is three shots, not two, with the fourth being the booster. For me, I have not seen a risk to getting the vaccine, and the risk if I get a serious case of Covid is much greater. I will definitely get the booster, I'm just waiting a bit longer because right now we are very much isolating so there is practically no risk. When Omicron is phasing out I will get my booster because it does appear as if the protection wanes over time.
JK

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