Have you received warning about Paxlovid from your transplant team?

Posted by bildad @bildad, Jan 10 7:25pm

I just received a warning from my liver transplant team concerning Paxlovid. It’s a Covid treatment drug from Pfizer. If one is taking immunosuppressants then Paxlovid is a no no. Ha y’all been warned about this?

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@leahdrose

I used to strongly believe in vaccines. I haven’t been tested for antibodies. I developed mild neuropathy on my hands and feet as side effect from my meds. I’m taking Tacrolimus, Prednisone and Cellcept that was recently switched to Myfortic. After my third vaccine, my neuropathy has gone from mild to worse. The tingling, pricking and itching are bothersome especially at night. I also feel random mild pain on my feet. Hopefully, it won’t develop to severe pain. Who knows for how long it will stay, will it go away or maybe get even worse. I discussed with my doctor and was prescribed Gabapentin. Given the strong meds I currently take, I didn’t want to add more to it; therefore, I’m not taking this new med for as long as I can tolerate the neuropathy. I have no plans on taking the fourth vaccine in fear that my neuropathy will further get worse. I’m keeping safe at home, and hardly go out. When I do go out, I wear N95 and stay away from crowds. I pray hard to protect me and my family from any variants.

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My 3rd dose is due. But I am seriously thinking of giving it a miss . I took Azrazeneca for the 2 doses . I simply dont want any complications.

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Does anyone find going to the Dentist these days a bit scary!!! Specifically is who are immunocompromised

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@nimalw

Does anyone find going to the Dentist these days a bit scary!!! Specifically is who are immunocompromised

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I try to think that they are the vulnerable ones this time, as here I am maskless and mouth wide open. They are always fully masked, sanitized, air purifier on…

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@nimalw

My 3rd dose is due. But I am seriously thinking of giving it a miss . I took Azrazeneca for the 2 doses . I simply dont want any complications.

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@nimalw I’m just sharing my experience. Of course, not everyone has side effects from the vaccine. I was reluctant to get the third vaccine because I was only 6 months post kidney transplant and my body could hardly tolerate the tons of meds. I pursued getting the vaccine although there’s no guarantee that immunocompromised would be protected. Unfortunately, in my case, the risk appears to be more than the benefit. It completely changed my opinion on vaccines upside down.

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@leahdrose

@nimalw I’m just sharing my experience. Of course, not everyone has side effects from the vaccine. I was reluctant to get the third vaccine because I was only 6 months post kidney transplant and my body could hardly tolerate the tons of meds. I pursued getting the vaccine although there’s no guarantee that immunocompromised would be protected. Unfortunately, in my case, the risk appears to be more than the benefit. It completely changed my opinion on vaccines upside down.

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Hi i am watching omricon progress. Let's see how it goes.. my doc said he lost a number of patients after transplant to delta variant. But omicron seems mild . Seems so with the very low death rate

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@bildad

And the public figures are just the ones we hear about. Keep your sails to the wind. It's great to be afloat with ya'll in these uncharted waters. Mind the boom when we come about! Because we likely will find all the jabs were in reality contraindicated.

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I have had very little reaction, mainly a couple of days just being tired, and I’ve had 3 doses. I plan on getting the fourth next month. I am a transplant patient on Cellcept, tacrolimus, and Prednisone. Although the vaccine won’t entirely prevent someone from getting Covid, it will prevent a severe complication requiring hospitalization and time on a ventilator in the ICU or death. The vast majority of hospitalized patients are those not vaccinated. My son chose not to be vaccinated because he has chronic Lyme disease and wound up very, very sick. He had a doctor that does home visits so he had infusions at home. Thankfully he’s recovering.

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I am not familiar with Paxlovid but I wanted to comment on a couple of other things that are being discussed in this conversation.

My personal suspicion is that if you are fairly recently transplanted then you are on a higher dose of immunosuppressants so will probably have fewer antibodies from the vaccines. I am 5.5 years out. After 3 shots my antibody count was 2032 U/ml which I think is fairly good. I also had it tested after my second shot and then it was only 13.82 so the third shot made a huge difference. My transplant team keeps my immunosuppressant as close to the lower end of the range as possible. I have had no problems.

Omicron is generally less severe than Delta but that is especially true for those of us who are fully vaccinated. The hospitals are at near capacity or close to it due to Omicron and patients who are not fully vaccinated. In my town, the students are still in school but the absenteeism with the students and with the teachers is extremely high. The schools seem to be real hotbeds of Covid.

I am at the point where I can get the booster – the protocol for immunocompromised patients is three shots, not two, with the fourth being the booster. For me, I have not seen a risk to getting the vaccine, and the risk if I get a serious case of Covid is much greater. I will definitely get the booster, I'm just waiting a bit longer because right now we are very much isolating so there is practically no risk. When Omicron is phasing out I will get my booster because it does appear as if the protection wanes over time.
JK

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