drug-resistant depression (DRD)

Posted by godsgirl1969 @godsgirl1969, Jan 16, 2018

I apparently have drug resistant depression : I have been on antidepressants for 20+ years some helped for awhile and now it seems like nothing helps. I also talk to a therapist once a week talking helps a little at least for that day. I am really wanting some insight from others that have struggled with this. I have been looking into ketamine injections or transcranial magnetic stimulation? Has anyone out there tried either of these and if so I would love to hear the effects it had? I’m tired of crying and tired of trying to get through every day!


Has anyone tried Abilify? My Dr. wants me to start on this along with Effexor xr

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@godsgirl1969 I have a friend that swears by Trintellix.


@charlie75 @godsgirl1969

I’m alive today thanks to good therapists and psychiatrists and the meds they’ve prescribed. I tried a string of meds and landed on Wellbutrin for my antidepressant and Klonopin for anxiety. Abilify didn’t do anything for me, but it helps many people. There’s a cheaper alternative. I recently started taking Mirtazapine as a secondary medication for depression, and it’s helped. It’s quite common to take a combination of antidepressants to achieve mental stability. I take pain meds, as well.


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@jimhd Hello Jim. May I ask how you found your good therapist and phychiatrist?


I can understand your situation as I’ve done a lot of research on medicines, etc, and how the meds treat different types of mental illnesses. Since I have no idea what your diagnosis might be, it is difficult to discuss treatment options. I have bi-polar 1, and I’ve tried to play doctor and treat myself. I would research different drugs and then discuss the drugs with my Doctor and most of the time he would change my meds. and then I would find myself in a worse situation. My Doctor had recommended a mood stabilizer sometime ago, and I nixed that idea due to the stigma of taking that type of drug. I finally found myself in a psych hospital and feeling suicidal. I decided to quit playing Doctor and listen to my Doctor. My Doctor prescribed a lesser dose of antidepressants and added the mood stabilizer. I have responded to this medicine and haven’t experienced the highs and/or lows that had filled my life for so many years. I hope you can find a solution that works for you.

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Have you considered looking into Genetic Testing for Psychotropic Medications and also Cognitive Behaviour Therapy? I would try those.
Best wishes

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