Thanks for the update @predictable. Given that you are about to start carvedilol (Coreg), you may want to read this thread started by @teatime http://mayocl.in/28YeSeN It includes a response by a Mayo Clinic pharmacist. @neeci and @teatime had to wean off the drug, but many use it successfully. We’ll be interested in your sharing your experience starting and finding your balanced dosage.

Martin: Thanks for the update. I wish you well as you pursue new treatments. I was not aware that DD and A-Fib were related, this will give me something to discuss with my cardiologist next month. My blood pressure tends to be low at times with a big gap between the diastolic and systolic numbers, perhaps that is related to the aortic insufficiency. I am planning on ordering that blood pressure monitor that has been discussed. I need to keep an accurate handle on what is happening. Please keep me posted on how your new med therapy is working for you.
Blessings,
Teresa

That does make sense. I also have diastolic dysfunction as a result of Hypertrophic Cardiomyopathy and I take a beta blocker and have for years. I do not have a fib, but beta blockers are a common medication for Afib as rate control is key.

http://mayoresearch.mayo.edu/center-for-individualized-medicine/pharmacogenomics.asp

Thanks for the reminder, @dawn_giacabazi. I want to finish preparing a request to my cardiologist, nephrologist, and urologist for approval of some pharmacogenomics (PGx) tests to see whether any of them — or my HMO — is prepared to add them to their protocols for a range of diseases. I’ll submit the first such request in about 2 weeks.

Martin

Teresa, I pursued the DD and A-fib link after seeing some research from Mayo suggesting that beta blockers could produce adverse effects in some more serious DD cases. It turns out that the threat of this is rare — not for those of us who have DD as a result of A-fib, according to my cardiologist, but in cases where there is moderate to serious DD but no A-fib. So he gave the green light for me to take Carvedilol.

Martin

You are welcome. Remember these particular test is not for diseases. This is to help determine the exact medications to treat you at the right drug, at the right dose & the right time to prevent over dose and drug interactions. To also help prevent diseases like liver & kidndy failure from taking wrong medications. 🙂

Yes, I should have said “for a range of therapies” rather than diseases, right?

I am sorry. I didn’t mean to correct you just want to make sure you knew it was more specific than testing diseases. That would be a whole different testing and a whole different set of guidelines and coverage by insurance.

No sweat! You’re right! Bad use of the word “diseases” by me.

Not good about your arrhythmia. But it is what it is. Fortunately, one of my early cardiologists suggested that beta blockers might not be good for my issues. Therefore, I have resisted them for years, along with CCBs and ACEs. Now the research seems to have caught up with this, according to the crews at Mayo-MI. You might catch some of their videos on cardiac, amyloidosis, etc. They are very, very good. Morie Gertz and Martha Grogan deal with this stuff often in videos and writings.

Hi Martin
Recently I started having high Diastolic numbers and feel nauseated or tired. Cardiologist tried 24 monitor and couldn’t find any afib

What additional tests should I ask him to conduct ?

My DP hovering around 90 and I feel nauseated when it does and can’t even do small things