XALKORI (crizotinib)

Posted by 2onlow8 @2onlow8, Oct 19, 2019

I’m getting switched off of Keytruda and Alimta to targeted therapy Crizotinib. Does anyone have any experience with this? Side effects? Success/failure? I’m told I have few options available.

@merpreb

@2onlow8– WHile we wait for someone to help with your questions about Xalkori I am wondering what you are doing to increase your lung capacity. It must be a relief to have found Xalkori. If I'm not mistaken Xalkori is a combo of chemotherapy and targeted therapy. Are you aware of some of these side effects below?
https://www.everydayhealth.com/drugs/crizotinib

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I am doing seated yoga and COPD breathing exercises to increase my lung capacity and weights to exercise my arms, exercise bands to move my legs.

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@2onlow8– Good morning. Good for you. You seem to have everything covered. There are also a number of good exercise videos on youtube if you get bored or run out of ideas. I'd also like to invite you to a new virtual walking group on Connect.
https://connect.mayoclinic.org/discussion/lets-go-walking-join-me-for-a-virtual-walking-support-group/
Do you get out and walk? If not there are exercises for people who can't walk outside or who need to sit in a chair. Is this something that you might be interested in?

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@merpreb

@2onlow8– Good morning. Good for you. You seem to have everything covered. There are also a number of good exercise videos on youtube if you get bored or run out of ideas. I'd also like to invite you to a new virtual walking group on Connect.
https://connect.mayoclinic.org/discussion/lets-go-walking-join-me-for-a-virtual-walking-support-group/
Do you get out and walk? If not there are exercises for people who can't walk outside or who need to sit in a chair. Is this something that you might be interested in?

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Yes I’ll check these links out. Thanks. Results of my most recent blood work this week show no change in my CEA. That may signal that Xalkori (Crizotinib) has stopped its effectiveness. My dr has no further treatment suggestions if this is confirmed by a CAT scan next month.

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@2onlow8– Oh those are words none of us want to hear, "no further treatment suggestions". Do you think that you will seek more opinions?

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I have Medicare and AARP UHC and it would have cost me an additional $9600/mo.

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@merpreb

@2onlow8– Oh those are words none of us want to hear, "no further treatment suggestions". Do you think that you will seek more opinions?

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@2onlow8–- Good morning. I am checking in to see how you are doing and if you have made any decisions about treatments given your last post!

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@merpreb

@2onlow8– Oh those are words none of us want to hear, "no further treatment suggestions". Do you think that you will seek more opinions?

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I have a 2nd opinion oncologist at MD Anderson, Jacksonville, who has been very supportive of me and my local oncologist's suggestions over the past 2 years of my treatments. I'm awaiting results of a PT scan I had on Friday and he will also get those scan results so I'm sure we'll have a conversation this week.

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@2onlow8

I have a 2nd opinion oncologist at MD Anderson, Jacksonville, who has been very supportive of me and my local oncologist's suggestions over the past 2 years of my treatments. I'm awaiting results of a PT scan I had on Friday and he will also get those scan results so I'm sure we'll have a conversation this week.

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@2onlow8– This is good to hear. Please keep us updated! Keep safe.

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You too — as well as all of us with this horrible 'underlying condition'.

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@merpreb

@2onlow8– Oh those are words none of us want to hear, "no further treatment suggestions". Do you think that you will seek more opinions?

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Very happy to report that last week’s PT scan showed remarkable improvements to my lungs after 3.5 months of Xalkori! But I am still very short of breath due to fluid build up and damage to my lungs. Thoracentisis being scheduled. So far so very very good 😷.

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