Combined K2 and D3 sourcing and dosage?

Posted by mayoconnectuser1 @mayoconnectuser1, Nov 14, 2024

Hi All,

Reading through a study from another related thread - one citation related to an aortic valve study (which did not find a benefit to K2 in previous patients in the study), noted, almost in passing they felt there may be evidence to suggest K2 does reduce the rate of calcium buildup and seemed to infer it might reduce arterial calcium.

Given these inferences, I thought perhaps may not hurt to try K2. Then, others mentioned combining K2 and D3.

Appreciate your thoughts on this, dosage, and where/which supplements do you buy?

Thanks!

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mone2 | @mone2 | Apr 8 10:51am

They have been doing lots of studies on the subject of K2 and coumadin levels, some for heart valves and some for kidney disease. There is one that specifically recommended upping the dose of coumadin to balance out the K2 effect so that the blood was getting thinned appropriately. I can't find that one now but it is out there.
https://pubmed.ncbi.nlm.nih.gov/7794122/
This one is from 2004
"This review also considers the available research upon warfarin when given to patients receiving hyperalimentation and what effects the vitamin K supplements may have. "
https://pubmed.ncbi.nlm.nih.gov/15568285/
This is interesting:
"Oral anticoagulation and VKORC1 polymorphism in patients with a mechanical heart prosthesis: a 6-year follow-up."
https://pubmed.ncbi.nlm.nih.gov/22592842/

inah21 | @inah21 | Nov 5 5:55pm

In reply to @njx58 "I'm having trouble getting definitive information on this. Some sources say that it's vitamin K1, not..." + (show)

@njx58 - I read its K1 which interferes with Warfarin. For Vitamin D3, VitaminK2 (MK-7) is the recommended partner. You also see that in most supplements being sold in the market.

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