Brinsupri (aka Brensocatib)

Posted by scoop @scoop, Aug 12, 2025

FDA approved Brensocatib today. Hooray for us. Let’s hope we have access to it as soon as possible and it gives us some measure of relief. Thank you to all the scientists and doctors and patients!
https://www.multivu.com/insmed/9347351-en-fda-approves-brinsupri-brensocatib

Interested in more discussions like this? Go to the MAC & Bronchiectasis Support Group.

Profile picture for Sue, Volunteer Mentor @sueinmn

@jnmy I can't say with regard too how Brinsupri will be handled long term. I can tell you that both my insurance company and my daughter's have pushed back against preventative therapy with certain meds. In my case, the doctor convinced them to change. In my daughter's case, her company would not budge and she is paying out-of-pocket using her HSA dollars.

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@sueinmn Thanks for your response. It’s always informative!

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I'm starting on Brinsupri for my Bronchiectasis and I would like to know from others their experiences with taking it and what side effects they noticed. Also I've heard that Carbocysteine is helpful for getting mucus. Thanks. Jim D.

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Profile picture for duncan2 @duncan2

I'm starting on Brinsupri for my Bronchiectasis and I would like to know from others their experiences with taking it and what side effects they noticed. Also I've heard that Carbocysteine is helpful for getting mucus. Thanks. Jim D.

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Hi, welcome to the group. Brinsupri has been discussed a lot here with people sharing their various experiences. The biggest takeaway is that it can take up to six months to fully work. I hope that reading through these comments might help answer some of your questions. If not, please post in one of those discussions so it’s easier to find the discussions.
https://connect.mayoclinic.org/discussion/brinsupri-follow-up/
https://connect.mayoclinic.org/discussion/brinsupri-experience-after-3-months/

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Profile picture for Sue, Volunteer Mentor @sueinmn

@jnmy I can't say with regard too how Brinsupri will be handled long term. I can tell you that both my insurance company and my daughter's have pushed back against preventative therapy with certain meds. In my case, the doctor convinced them to change. In my daughter's case, her company would not budge and she is paying out-of-pocket using her HSA dollars.

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@sueinmn I was able to use the copay assistance program through the manufacture.

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