My Dr wants to switch me to a new medication - Entresto

Ive been on entresto for a month now. It dropped my bp a little when i first switched from the lisinopril. Ive had arm pain for the last few years now. I contribute it to low circulation, stress, and back pain. None of my meds have improved my ef mostly just help with the symtoms. If anyone finds out how to not be tired and crabby all the time i could use the help.

I know how you feel. On some days, I can't even do laundry or make a meal. I don't think there is an easy answer. Maybe in time the Entresto will give you more energy as you continue to take it. If you have a decent day, try to do a little more. Let us know how you are doing. Good luck.

Interesting to read the comments in here, I'm still researching what is Entresto and there are not much information available out there yet. My cardiologist just recently added Entresto 24/26 (2x) on top what I'm currently taking Carvedilol 3.125 (2X) Furosemide 40mg, Simvastatin20mg, and Warfarin 2mg. I noticed that after taking Entresto my BP systolic went under 100 and my heart rate went up from 70's to 96 is this normal? I have 2 valve replacement and a bypass and checking my BP every other day. When I walk to my car ( 150 ft away ) my heart beat faster it didn't before.

I thought you might be interested in learning more about this clinical trial from Mayo Clinic, (which is open for participation): https://clinicaltrials.gov/ct2/show/NCT03506412
The NIH-funded trial will evaluate the the efficacy of Entresto in patients who’ve been diagnosed with a stiff heart – research studies have shown that Entresto may help improve HFpEF.

Hi, I just joined this group and am trying to decide whether to switch to this med. I'm currently on lisinopril, carvidilol, spironolactone, lasix, 1/2 aspirin. My ejection fraction is in the 30's and I have been doing well on this regimen for the past 8 years. My blood pressure is usually low. At my last appt., my doctor told me he wants me to try Entresto. I'm worried about changing the status quo and about dropping my pressure even more and about raising my potassium levels.

Hello again, everyone,

After taking Entresto for 6 months, I just had another ECHO, which showed that my EF of 20 went down to 18. I also have no improvement in symptoms. I told my cardiologist I wanted to go off Entresto, but he insisted I stay on it. He said I might feel worse if I go off it.
Does anyone have any experience with this drug?
Thanks.
Corjianne

I am on spironolactone and I’m going through a horrendous cold or flu But know that I am not supposed to take the standard decongestant take medications. I have been suffering by just taking Mucinex and Celine nasal spray but wonder if anyone knows if there’s an affective decongestant that safe with spironolactone? Thanks!

my dr. change losartan to Entresto start with 24mg to 49mg after 3 months, i have lot of problem with this medidation i had always a fatigue, sensation of vertige, flue vission, stomack pain, my nose running almost all the time. this medication not good for me, imy doctor insist, he change me to 24mg,,i want realy to changed, what is the better than that.?

Hi, I've been on Entresto since Aug 29th 2019. I am on 49-51 mg twice a day. This has been a great medication for me. Like past medications, I've NOT had any side effects. I've found out many times myself that discussing your physical side effects is better to discuss first with pharmacist . They offer a lot of insight to these medications especially new ones on the market. When a pharmacist asks you if you have any questions about your medication when you pick it up, ASK HIM!!! He really means it.

There was a new medication that came out in 2005 and the Doctor's were prescribing this to everyone, thinking this was the cure of all evil. For me, the Doctor was prescribing way to much, to the point I was passing out. They couldn't even get a blood pressure.

Since my Doctor would not listen to me I discussed this with my pharmacist. Well low and behold, I was over medicated!!! My hair was falling out!!! Got a new phycisan and was taken off this completely.

I can say being on Entresto has changed my life and for the first time my heart beats wonderful. It straighten out my first A-fybulation this past summer. Since I was diagnosis with heart disease at 55 years old.

My advice check with your pharmacist and online for those side affects. Then, sit down with your physician and have a one to one meeting with him to discuss these issues. Have scheduling set aside a half an hour to meet with him. If you don't get the results you are searching for need, it is time to find another doctor who cares about his patients. There out there.

One more suggestion, many people who are on heart medications don't set up 6 month examines with their primary doctors which is very important because, they can offer a lot of assists in resolving these issues. I know, my primary physician is very proactive for me. And another point, have your blood work done every 6 months because medication can reduce vitamin levels. For me my Vitamin D3 fell in the hole and today it is finally reaching a normal level.

The very best in getting this issue solve. I know from my cardiologist he starts everyone on a low dosage for 6 months and slowly raises the dosage. When, I begin to show signs of side of effects, he reduces me back.

Hope this helps. With God's Warm Blessings, Maddie

I am have CHF, Cardiomyopathy, and LBBB , I currently take Faxiga, and Metropolo 75mg, I could not tolerate 100mg, I had an echo, with EF the same at 40% and I actually did a little worse on the treadmill, we are trying a 2nd trial of Entrest with 1/2 of the lowest dose twice a day, since starting I am breathless with very little activity and so fatigued, I feel very different than before Entresto, the Dr is talking about a possible pacemaker even though my EF is 40% but we trying meds first, she wants an hemodymanic treadmill test to check the blood flow in my heart when the LBBB is present when my heart rate goes above 100. I talked to the cardio nurse today and I am just so frustrated! Anyone have any experience with this?