How long did you take a statin before feeling side effects?

Posted by swilkins1974 @swilkins1974, May 24, 2023

How long did you take a statin before you started feeling side-effects?

Interested in more discussions like this? Go to the Heart & Blood Health Support Group.

@mayoconnectuser1

So, your HDL increased by 50% due to diet? This seems out of the norm for HDL movement ... for any reason.

I've seen reports where HDL increases a bit by increasing exercise, and better diet, but, 50% is a HUGE movement for HDL?

40 is considered "Good" in some medical articles, with 60 being consider "High."

Jump to this post

It most certainly was possible for me. My HDL has been between 75-82 mg/dl for the past four years. For the ~ 15 years before that, it ran 42-51 mg/dl.

What changed? I lost 55 lbs on a low-carb diet combined with daily exercise. And I have kept it all off without any backsliding. And my rosuvastatin dose has been halved.

REPLY
@whineboy

It most certainly was possible for me. My HDL has been between 75-82 mg/dl for the past four years. For the ~ 15 years before that, it ran 42-51 mg/dl.

What changed? I lost 55 lbs on a low-carb diet combined with daily exercise. And I have kept it all off without any backsliding. And my rosuvastatin dose has been halved.

Jump to this post

Wow - great job changing your lifestyle!

Here are a few articles with mention of extremely high HDL ... I can't interpret this, but your HDL seems incredibly high based on my limited knowledge. At least one of the articles refers to a Danish study that indicated lowest mortality in men of an average of 73 - so, you're right there. Other articles infer you are pretty high and should review other factors. Again, I'm not qualified to comment further.
https://my.clevelandclinic.org/health/articles/24395-hdl-cholesterol#:~:text=An%20elevated%2C%20or%20abnormally%20high,trouble%20getting%20rid%20of%20it.
https://www.webmd.com/cholesterol-management/good-cholesterol-too-high
https://www.uspharmacist.com/article/common-otc-drugs-supplements-potentially-can-confound-laboratory-results-1-1
https://www.heartuk.org.uk/genetic-conditions/high-hdl-cholesterol
https://pubmed.ncbi.nlm.nih.gov/35039162/
https://academic.oup.com/eurheartj/article/38/32/2478/3608700

REPLY

Thanks for your concern. I have my annual cardiologist visit in a month and can ask if HDL can be too high.
I saw the hazard ratio on one of the srudies was 1.44 - that’s barely significant, my understanding is that the HR has to be 2.5 or better to be meaningful.
Edit: I also understand it’s a function of my low-carb eating.
Edit 2: You inspired me to look over my most recent lab results. They show my HDL is in the green and there is no high-end limiting value. Still, worth checking up on, I agree.

REPLY
Please sign in or register to post a reply.