How long did you take a statin before feeling side effects?

Posted by swilkins1974 @swilkins1974, May 24, 2023

How long did you take a statin before you started feeling side-effects?

Interested in more discussions like this? Go to the Heart & Blood Health Support Group.

@mayoconnectuser1

So, your HDL increased by 50% due to diet? This seems out of the norm for HDL movement ... for any reason.

I've seen reports where HDL increases a bit by increasing exercise, and better diet, but, 50% is a HUGE movement for HDL?

40 is considered "Good" in some medical articles, with 60 being consider "High."

Jump to this post

It most certainly was possible for me. My HDL has been between 75-82 mg/dl for the past four years. For the ~ 15 years before that, it ran 42-51 mg/dl.

What changed? I lost 55 lbs on a low-carb diet combined with daily exercise. And I have kept it all off without any backsliding. And my rosuvastatin dose has been halved.

REPLY
@whineboy

It most certainly was possible for me. My HDL has been between 75-82 mg/dl for the past four years. For the ~ 15 years before that, it ran 42-51 mg/dl.

What changed? I lost 55 lbs on a low-carb diet combined with daily exercise. And I have kept it all off without any backsliding. And my rosuvastatin dose has been halved.

Jump to this post

Wow - great job changing your lifestyle!

Here are a few articles with mention of extremely high HDL ... I can't interpret this, but your HDL seems incredibly high based on my limited knowledge. At least one of the articles refers to a Danish study that indicated lowest mortality in men of an average of 73 - so, you're right there. Other articles infer you are pretty high and should review other factors. Again, I'm not qualified to comment further.
https://my.clevelandclinic.org/health/articles/24395-hdl-cholesterol#:~:text=An%20elevated%2C%20or%20abnormally%20high,trouble%20getting%20rid%20of%20it.
https://www.webmd.com/cholesterol-management/good-cholesterol-too-high
https://www.uspharmacist.com/article/common-otc-drugs-supplements-potentially-can-confound-laboratory-results-1-1
https://www.heartuk.org.uk/genetic-conditions/high-hdl-cholesterol
https://pubmed.ncbi.nlm.nih.gov/35039162/
https://academic.oup.com/eurheartj/article/38/32/2478/3608700

REPLY

Thanks for your concern. I have my annual cardiologist visit in a month and can ask if HDL can be too high.
I saw the hazard ratio on one of the srudies was 1.44 - that’s barely significant, my understanding is that the HR has to be 2.5 or better to be meaningful.
Edit: I also understand it’s a function of my low-carb eating.
Edit 2: You inspired me to look over my most recent lab results. They show my HDL is in the green and there is no high-end limiting value. Still, worth checking up on, I agree.

REPLY

About 2 weeks I couldn’t take it any more my legs got weak and a terrible mind cloud, then horrible blood bruising on my arms, fatigue. I’d rather die have a heart attack than live like this. I thought doctors were not to do no harm. So I stopped before permanent damage, so glad I did. Finally went to another, again I told her, I can’t take them and she calls in a script for same. I am in charge of my body and there has to be something else. Haven’t they heard of quality of life? I don’t do harmful drugs.

REPLY
@whineboy

Thanks for your concern. I have my annual cardiologist visit in a month and can ask if HDL can be too high.
I saw the hazard ratio on one of the srudies was 1.44 - that’s barely significant, my understanding is that the HR has to be 2.5 or better to be meaningful.
Edit: I also understand it’s a function of my low-carb eating.
Edit 2: You inspired me to look over my most recent lab results. They show my HDL is in the green and there is no high-end limiting value. Still, worth checking up on, I agree.

Jump to this post

It does come down to diet, been heavy on the carbs lately and sedentary due to back issues, My blood work indicates liver function issues and Dr prescribed a statin? Before a change in diet and exercise? Why would I poison my liver function even more before a change in diet?

REPLY

It wasn’t sudden, but cumulative. I just felt bad and weak at first and then my back started hurting and I went to PT. Pain moved into my hips, elbows and hands. I couldn’t open water bottle tops. I went to OT and acupuncture. Did lots of exercises. It kept progressing. I had horrible pain rolling over in bed, getting out of bed. I couldn’t pick up my young grandchildren. I tried telling my doctors and they told him I would adjust in time. Cardiologist cut me back to 3times week on the statin. Switched to a different statin. This went on for two miserable years. The only good that came of it was getting my number down. I finally got the ok from primary to take a statin break and cardiologists agreed. The pain did not miraculously go away, but gradually over 3-4 weeks, I felt so much better. I’ve regained function and quality of life. It’s been 4 months and my numbers are high again so he wants me to try Zetia, and maybe Repatha. Not sure what the answer is but I won’t take statins again.

REPLY

I started with 20mg Crestor and did fine for about 6-8 weeks, then my legs started feeling very weak. My LDL dropped to 45 which was great, so I dropped to 10mg and eventually to 5mg but side effects persisted. Finally, my cardiologist recommended Praluent, which was a huge mistake. Side effects have been horrible and I ended up in urgent care. Praluent stays in the body for over 100 days. I stopped 40 days ago and I feel much better but I still get brief episodes of intense fatigue and leg/muscle weakness.

REPLY

You can feel minor side effects within a couple days. Headache, nausea etc. Serious side effects could take weeks, so stay on top of your lab work. I’m on rosuvastatin and am dealing with headaches. Been a month now, but my cholesterol levels have responded very well.

REPLY
@mikesto

You can feel minor side effects within a couple days. Headache, nausea etc. Serious side effects could take weeks, so stay on top of your lab work. I’m on rosuvastatin and am dealing with headaches. Been a month now, but my cholesterol levels have responded very well.

Jump to this post

I've been taking 10 mg rosuvastatin for two months, and I've felt nothing.

REPLY

Interested in what others have to share. Is there a natural alternative to statins? My doctor has been talking about them to me, but the side effect profile isn't great.

REPLY
Please sign in or register to post a reply.