MTHFR Mutation

Posted by doriejean @doriejean, Feb 3, 2023

I was born with MTHFR Mutation. I've had all the symptoms of this mutation all my 82 years of life including mental illnesses.
I now have a Southern Illinois Medical School professor who understands this disease and has ease the symptoms that have plagued me all my life.

Interested in more discussions like this? Go to the Autoimmune Diseases Support Group.

Profile picture for MidwestHappiness @femalepersuasion

I think it's methyl B complex. I had a great chewable from Amazon called EZ Melts I used to take. I have the MTHFR gene too.

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Thank you for responding. From what I've been reading, the Methyl B12 is a better option.

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Profile picture for contilucy1960 @contilucy1960

I have been taking up to 11 vitamins and supplements a day as prescribed by a doctor 7 years ago, due to MTHFR gene mutation. I would like to update what supplements and vitamins are needed for this condition. Any input welcome!

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In addition to Heterozygous MTHFR C677T, I have Sjogren's Disease. I am specifically concerned about the connection to non-Hodgkins Lymphoma, of which my father died at the age of 41. Additionally, my mother died of Ovarian cancer (age 67), paternal aunt from Breast Cancer, age 66, brother from Liver cancer age 61, other brother survived prostate cancer.
I have gluten allergy, lactose intolerance, osteoporosis, high cholesterol (313, being treated with Simvastatin and Ezetimibe).
I do take supplements and jog 7 miles a day.
I am 5' and weigh 99 lbs.
Female , Age 70
Throughout my life, I have had repeated re-occurrences of laryngitis which turn into pneumonia.
With Sjogrens and Heterozygous MTHFR C677T, what should I be doing to stay healthy, especially in the winter months.
The Sjogrens has exacerbated causing wacko temperature swings and I often go from feeling freezing cold to burning hot within minutes.
I try to stay away from anyone sick as these auto-immune diseases wipe me out when triggered.

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Profile picture for contilucy1960 @contilucy1960

I have been taking up to 11 vitamins and supplements a day as prescribed by a doctor 7 years ago, due to MTHFR gene mutation. I would like to update what supplements and vitamins are needed for this condition. Any input welcome!

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Hi ! I am new to the post and community here. I came across this while searching for the MTHFR mutation. All I was told by my gp was I have the mutation but homocysteine is within range and bit b12 is high. Which is due to the mutation . He’s thinking Hashimoto (?) . Any advice - Ty in advance!

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Profile picture for contilucy1960 @contilucy1960

I have been taking up to 11 vitamins and supplements a day as prescribed by a doctor 7 years ago, due to MTHFR gene mutation. I would like to update what supplements and vitamins are needed for this condition. Any input welcome!

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Can anyone recommend drug/drugs that may be helpful in tapering off of Tramadol?

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Profile picture for bisma80 @bisma80

Hi ! I am new to the post and community here. I came across this while searching for the MTHFR mutation. All I was told by my gp was I have the mutation but homocysteine is within range and bit b12 is high. Which is due to the mutation . He’s thinking Hashimoto (?) . Any advice - Ty in advance!

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I have this and so does my adult son. For my case and his, our diet had to change big time. I also have had my thyroid removed and parathyroid many years ago as it was so unstable. Synthroid ever since so I could check that box off. The covid shots through my body into a mess, and my son and I both had huge reactions. MTHFR was mentioned to both of us in two different states. We both ended up with holistic medicine doctors to deal with Mast Cell Activation and the supplements required to correct out chemistry . Their protocols were excellent. Take a look at Becky Campbell’s amazing site, and Beth O’Hara’s.. There are many sites around the entire world for MCAS . I use Becky’s supplements called Optimal Reset, and they are a Godsend for correcting . MTHFR is very good at causing weird upsets! I react to everything and have a long allergy list. My adult son actually went into anaphylactic shock from it after one of his covid shots. I was very sick after each shot. I hope you check out the web sites for MCAS and see if that has any ah ha moments for you! Good luck!

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Profile picture for Amanda Burnett @amandaa

Hi @contilucy1960

Glad you are trying to stay on top of your MTHFR with added supplements. I am not entirely sure of all the supplements that you need to be taking, but here are some sites that may give some insight.

MTHFR Diet, Lifestyle, & Supplements: https://www.cleaneatingkitchen.com/mthfr-diet-lifestyle-supplements/

What You Need to Know About the MTHFR Gene: https://www.healthline.com/health/mthfr-gene

MTHFR Gene, Folic Acid, and Preventing Neural Tube Defects: https://www.cdc.gov/ncbddd/folicacid/mthfr-gene-and-folic-acid.html

Are you also trying to avoid harmful foods with this mutation such as enriched grains, like pasta, cereals, breads, and commercially produced flours?

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I have MTHFR from mom and dad. Does it have to be from both or can one parent have te gene?

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Profile picture for contilucy1960 @contilucy1960

I have been taking up to 11 vitamins and supplements a day as prescribed by a doctor 7 years ago, due to MTHFR gene mutation. I would like to update what supplements and vitamins are needed for this condition. Any input welcome!

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Hi everyone, I tested positive for homozygous A1298C MTHFR. l am 56 years old and live in central FL. My whole life I have been plagued with sinus infections, chest infections, asthma. I feel like I am the healthiest unhealthy person in the world. Is it more helpful to see an MD or a nutritionist? Can anyone recommend a professional in central florida who knows how to treat this? Thank you.

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So glad you found someone who understands. How did they help you ease your symptoms?

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Can you share with us what has helped you ? I have this gene also .

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@doriejean, I add my welcome. Like @grandmad, I'd be interested in learning more about your experience with managing symptoms related to the MTHFR mutation. What symptoms were you experiencing? How has your new team helped?

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