MTHFR Mutation

Hi,
Relieved to be in contact for the first time with other people with this enzyme issue MTHFR.
Simple cure for me , I take a dietary supplement made by
Compound Labs in Auckland New Zealand called L-Methionine and I take 1500mg which most take as their dose per day.It can be sourced from food like chicken, tuna, salmon etc but I would never get enough to do the job.I feel normal now and any so-called mental health symptoms vanished as soon as I took it.I also take B6 and zinc due to found deficiencies via blood tests.All of this prescribed by Dr David Codyre, you can find him in Google search.

Be careful with B6…if you feel any numbness in your fingers or toes, it may be the B6…I can cause neuropathy and may cause permanent damage…

I found out recently due to my daughter having this mutation, that I also have it. I was diagnosed with Hashimoto’s and Hypothyroidism about 2 years ago and take Synthroid to manage the Hypothyroidism. Is there anything else I should be testing for? New to this, thanks!

Hay
When I first found out my mthfr0677TT, 70 percent inability to absorb folic acid, I learned a lot from the book Dirty Genes. I now read medical articles and research to see what role the gene mutation has contributed to all my other medical issues. They all are interconnect. Usually people take methylfolate and methylcobaline typo spelling and B6. B vitamins are water soluble, however b6 you can become toxic on. It’s in everything sport drinks, good, Rx , complex supplements, even in magnesium. Thus is what I get tested for : B12 and Homosyteine, and MMA( methalomonic acid) , folate serum, and B6. With the 0677TT your folate and b12 only show what is in your blood stream. Since the mutation is about your inability to absorb, you need to test homosystein levels and MMA to gain better accuracy of how much you are absorbing. Everyone ideal levels are different. Usually people with MtHFR double copy it’s noted that homocysteine levels stay around 7. When mine go to 14 I know I’m deficient in my folate and b12. It’s been tricky for me to fine my right dosing and blood levels. Most doctors are clueless about reading levels in mthfr. I have neuropathy bc I was told my b12 levels were fine. Now I understand why they were actually very low. MtHFR can indirectly effect thyroid as well. when my folate and b12 get out of balance, my thyroid acts up more toward hypo. Now I’m looking into autoimmune thyroid issue. MtHFR has also contributed to my iron deficiency and low platelets and low Ferritin. I get iron infusions and so I also have to get those labs tested. . Be mindful of all medications and OTC that deplete folate and b12. I have to look up everything before taking. Stay away from FOLIC ACID. 0677Tt can not absorb it causing it to float around in your blood stream unused causing more issues. Read labels on foods drinks, otc to avoid folic acid. Only take methyl folate formula. FYI: its helpful to type in my gene mutation and ask google for research articles effecting each medical issue I’m having. Very insightful and helpful to show my doctors. Best wishes.
We all have good and bad genes. Genes get turn on and off according to so many factors we are exposed to. Supplementing manages the MtHFR gene. But many factors can throw it out of wack. Stress, surgeries, medications, lifestyle, diet. Etc. Hope some of this helps.
The Dirty Gene book was helpful to see what to test for and more. Easy reading.
Blessing to you

Hay
When I first found out my mthfr0677TT, 70 percent inability to absorb folic acid, I learned a lot from the book Dirty Genes. I now read medical articles and research to see what role the gene mutation has contributed to all my other medical issues. They all are interconnect. Usually people take methylfolate and methylcobaline typo spelling and B6. B vitamins are water soluble, however b6 you can become toxic on. It’s in everything sport drinks, good, Rx , complex supplements, even in magnesium. Thus is what I get tested for : B12 and Homosyteine, and MMA( methalomonic acid) , folate serum, and B6. With the 0677TT your folate and b12 only show what is in your blood stream. Since the mutation is about your inability to absorb, you need to test homosystein levels and MMA to gain better accuracy of how much you are absorbing. Everyone ideal levels are different. Usually people with MtHFR double copy it’s noted that homocysteine levels stay around 7. When mine go to 14 I know I’m deficient in my folate and b12. It’s been tricky for me to fine my right dosing and blood levels. Most doctors are clueless about reading levels in mthfr. I have neuropathy bc I was told my b12 levels were fine. Now I understand why they were actually very low. MtHFR can indirectly effect thyroid as well. when my folate and b12 get out of balance, my thyroid acts up more toward hypo. Now I’m looking into autoimmune thyroid issue. MtHFR has also contributed to my iron deficiency and low platelets and low Ferritin. I get iron infusions and so I also have to get those labs tested. . Be mindful of all medications and OTC that deplete folate and b12. I have to look up everything before taking. Stay away from FOLIC ACID. 0677Tt can not absorb it causing it to float around in your blood stream unused causing more issues. Read labels on foods drinks, otc to avoid folic acid. Only take methyl folate formula. FYI: its helpful to type in my gene mutation and ask google for research articles effecting each medical issue I’m having. Very insightful and helpful to show my doctors. Best wishes.
We all have good and bad genes. Genes get turn on and off according to so many factors we are exposed to. Supplementing manages the MtHFR gene. But many factors can throw it out of wack. Stress, surgeries, medications, lifestyle, diet. Etc. Hope some of this helps.
The Dirty Gene book was helpful to see what to test for and more. Easy reading.
Blessing to you

What type of doctor do you see for this? I see an integrative medicine MD, who doesn't seem very concerned about it.